脓细胞

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，"PMN-EC"相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

Objective To study the correlating factors which promote HPV6.11/16.18 infection , such as pH,clearing degree, leukocyte, pyocyte, mycetes, infusorian, clue cell et al.

目的 探讨pH值、清洁度、白细胞、脓细胞、霉菌、滴虫、线索细胞等因素中，与HPV6.11/16.18感染和加速感染进程的相关因素。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells, caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells, and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue, cells and mucous oweing to hardness to get puncture, neans tuberculous restoration,and scar formation.

结核初期-炎性增殖期60例，占5.5%；结核早期-淋巴结节期130例，占11.9%；结核中期-结核性结节期有590例，占54.1%；结核晚期-干酪样脓样坏死期有280例，占25.7%；结核恢复期-纤维素增殖期30例，占2.8%。炎性增殖反应期非特异性形态学变化，需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断，结核结节期主要可有较多类上皮样细胞及郎罕氏细胞；而干酪样脓样坏死主要见大量坏死组织及碎屑、少数残碎不全类上皮样细胞，此期主要能查到抗酸菌为特点；纤维增殖期，抽出物难取，仅见少数纤维组织、纤维细胞和黏液间质为其特征，提示结核恢复、瘢痕形成所致。

After salpingitis tubal atresia adhesion, mucosal cells in the secretion of fluid accumulation within the lumen, or isthmic tubal inflammation and adhesions umbrella side, blocking the formation of fallopian tube, when the lumen is absorbed within the suppurative cells , after eventually become liquid water.

在输卵管炎后，因输卵管粘连闭锁，粘膜细胞的分泌液积存于管腔内；或因输卵管炎症发生峡部及伞端粘连，阻塞后形成输卵管积脓，当管腔内的脓细胞被吸收后，最终成为水样液体。

Logistic regression analysis and multiple factor variance analysis showed clearing degree and H2O2 concentration promoted HPV6.11/16.18 infection and speeded infection process. But pyocyte, mycetes, neuraminidase had no dependability with HPV6.11/16.18 infection.

Logistic回归和多因素方差分析结果表明，清洁度和H2O2浓度与HPV6.11/16.18感染和加速感染进程密切相关，与脓细胞、霉菌、唾液酸苷酶并无相关性。pH值、白细胞、霉菌、滴虫、线索细胞、白细胞酯酶与HPV6.11/16.18感染虽无相关性，但在引起HPV6.11/16.18感染方面起到重要作用。

Results the positive rate of hpv6.11,hpv16.18,hpv6.11/16.18 were 52（25.4%）、45（22.0%）、26（12.7%） respectivelys. logistic regression analysis and multiple factor variance analysis showed clearing degree and h2o2 concentration promoted hpv6.11/16.18 infection and speeded infection process. but pyocyte, mycetes, neuraminidase had no dependability with hpv6.11/16.18 infection.

结果 205例疑似尖锐湿疣感染患者检出hpv6.11、hpv16.18、hpv6.11/16.18阳性例数为52、45、26.logistic回归和多因素方差分析结果表明，清洁度和h2o2浓度与hpv6.11/16.18感染和加速感染进程密切相关，与脓细胞、霉菌、唾液酸苷酶并无相关性。ph值、白细胞、霉菌、滴虫、线索细胞、白细胞酯酶与hpv6.11/16.18感染虽无相关性，但在引起hpv6.11/16.18感染方面起到重要作用。

Pyocyte; pus cell; pus cells

&脓细胞&；英文对照

The content of MIF in heart and kidney tissues of sepsis models was higher than that in the sham group, especially from the twelfth hour to forty-eighth hour after CLP. It indicates that MIF as a kind of late cytokine might participate in dysfunction of organs in mice with sepsis.

脓毒症发生后的12 h~48 h，MIF在脓毒症小鼠心脏和肾组织中的表达有不同程度增加，表达时相基本一致，提示N1F可作为晚期细胞因子参与小鼠脓毒症的发病。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池，将lipid A包被于非衍生样品池，分别建立以PGN、CpG DNA及lipid A为靶点的技术平台，对114种抗炎中药水提物进行筛选、评价其活性物质含量，并评估出针对上述三种病原分子均具有较高结合活性的中药；(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术，从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分；在体外实验中，测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力；MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响；ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用；在体内实验中，采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌，建立细菌脓毒症小鼠模型，观察活性组分对脓毒症模型小鼠的保护作用。

Result:The effect of Niaoluqing on chronic urethritis was better than that of Sanjing Pian,the difference was significant.Niaoluqing could clear away the WBC,RBC,and pus cell in the urine,reduce the level of IgG,β2-MG,ALb in the urine,rapidly relieve the stimulus of urethra,improve the function of immunity.

结果：提示尿路清组显效率明显高于三金片组，对多种细菌导致的泌尿系感染作用良好，能很快清除尿中白细胞、红细胞、脓细胞，使尿中IgG、β2-MG、ALb指标下降，迅速解除泌尿系刺激症状，并改善免疫功能。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。