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Mutant mice than in wild-type controls, and tetrodotoxin or bicuculline application abolished the difference between the genotypes. Studies on human oligodendroglioma cells revealed that GABA played a protective role on Ca〓 overload induced by OGD or glutamate and phaclofen, GABA〓 receptor antagonist, could significantly block the protection.

结果表明:①电凝大脑中动脉后Ca〓2.3-/-鼠脑梗死率和缺血后运动障碍明显重于Ca〓2.3+/+鼠;②Ca〓2.3-/-鼠海马脑片CA1区缺氧后钙超载明显高于Ca〓2.3+/+鼠;③Na〓通道阻滞剂TTX和GABA〓受体阻断剂bicuculline可显著缩小遗传表型之间的差异;④GABA对缺氧无糖及谷氨酸所致的人胶质细胞瘤细胞Ca〓超载有明显的保护作用,此作用可被GABA〓受体阻断剂phaclofen拮抗。

Methods 80 patients of acute cerebral infarction were divided into the treated group and the check group, the treated group was treated with alprostadil injection,and the check group with the compound danshen injection、low-molecular-weight dextran.collect the result of hemorheology of cerebral infarction and nail fold microcirculation in anterior circulation and posterior circulation.

将80例脑梗塞患者随机分成治疗组和对照组,治疗组予以凯时注射液,对照组予以复方丹参、低分子右旋糖酐治疗。于治疗前后分别测定血液流变学及甲襞微循环的各项指标。

Furthermore, pre-exposure of the slice to CORT lead to reduction of LTP in Novel rats and this reduction was also laterialized to the right hippocampus.

将脑片预先灌流100 nM糖皮质激素,随后记录LTP明显减小,这种减小也明显偏向于右侧。

Objective To explore clinical effect of monosialotetrahexosylganglioside (GM1) in the treatment of acute cerebral infarctions.

目的 探讨单唾液酸四己糖神经节苷脂(GM1)治疗急性脑梗塞的临床疗效。

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