脑硬化

Without any other methods can measure the character of the live white matter presently, DTI has great significance for the study of the anatomization of the brain and the diagnosis of the diseases of white matter.

根据此特性，DT-MRI技术在显示脑白质的微观组织结构和纤维束走向等方面具有极大的优越性，作为目前唯一的非侵入性分析大脑内部结构的重要工具，DT-MRI已经在中风、老年痴呆症、精神分裂症、脑缺血以及多发性硬化症和其他一些脑部肿瘤的研究和诊断中发挥了重要的作用。

Antigangliosides GM1 antibody and cephalin antibody in serum (n=28) and cerebrospinal fluid (n=18) were examind in MS patients with ELISA assay.

采用ELISA方法测定多发性硬化患者活动期血清(28例)和脑脊液(18例)的GM1抗体、脑磷脂抗体和髓鞘碱性蛋白。

Hooper, previous studies by his group and other researchers have shown that blood-brain barrier permeability is critical in the development of MS.

为了研究血脑屏障的通透性，他和他同事们观察到多发性硬化进展过程中血脑屏障的损伤起到关键作用。

Less common associations are with hypoparathyroidism, pseudo-hypoparathyroidism, Fahr's familial idiopathic cerebral calcificatinon, birth anoxia, carbon monoxide intoxication, lead poisoning, Tuberous Sclerosis, Cockaynes syndrome, postinfectious encephalomyelitis, AIDS, radiation therapy, methotrexate, mitochondrial disease (Kearns-Sayer), and, as in the case shown here, Down's syndrome.

脑钙质沉着与以下疾病有着非普通联系：甲状旁腺机能减退，假甲状旁腺机能减退，Fahr's家族特发性脑钙化，出生缺氧症，一氧化氮中毒，铅中毒，结节硬化症，科克因综合征，流行性感染后脑脊髓炎，艾滋病，放疗，氨甲喋呤，线粒体病，以及Down's综合症。

The purpose of this study was to investigate the extracranial carotid stenosis in Chinese patients with ischemic stroke by means of computerized tomographic angiography and ultrasonography .

目的颈动脉粥样硬化是脑梗死的主要发病原因之一，本文比较CT血管造影和颈动脉超声技术检测缺血性脑梗死患者颅外颈动脉狭窄的情况。

This area of firm, whitened gyri that are broader than surrounding normal gyri is typical for tuberous sclerosis.

结节性硬化症，变硬变白的脑回比周围正常的脑回宽是其典型表现。

People often occur in elderly vascular sclerosis, high blood pressure sustained more easily lead to cerebral arteriosclerosis, vessel wall hyalinization appears fat, thus weakening the strength of the vessel wall, together with the blood of the structure of the wall is relatively weak, the middle vascular myocytes less, the lack of external elastic layer developed arterial adventitia easily occurred in the brain artery wall limitations small expansion, the formation of micro-miliary aneurysm.

人到老年血管常会发生硬化，持续的高血压更容易导致脑动脉硬化，血管壁出现脂肪玻璃样变，从而削弱血管壁的强度，加上脑血管壁的结构比较薄弱，血管中层肌细胞少，缺乏外弹力层，动脉外膜不发达，容易造成脑内小动脉壁发生局限性扩张，形成粟粒性微动脉瘤。

Recent research showed,different genotype of ApoE has various affect to lipometabolism,forming of arterial sclerosis and cardiovascular disease,meanwhile ApoE is also related to disease of center nervous system such as cerebral infarction,Alzheimer disease,multiple sclerosis and schizophrenia.

近年来的研究发现，ApoE不同基因型对脂质代谢、动脉硬化及冠状动脉粥样硬化性心脏病有影响，同时与中枢神经系统疾病如脑梗死、阿尔茨海默病、多发性硬化等，以及精神分裂症有关。

Cerebral malacia in 10.7%, developmental abnormalities in 10.5%, perinatal brain injury in 8.1%, mesial temporal sclerosis in 5.4%, brain tumor in 4.9%, and the other in 15.0%.

进一步研究表明20岁以下的患者以脑发良不良、围产期损伤、颅内感染、海马硬化多见，而20岁以上患者以颅内感染、脑外伤、脑血管病多见。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后，血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少，Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少，血小板聚集程度及红细胞聚集指数显著上升，病理切片显示胸主动脉内皮细胞破坏明显，脑心肾组织内的血管进一步增厚甚至几乎阻塞，导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR，脑体重比显著升高；心肌内出现明显的缺血梗塞疤痕灶，心体重比显著升高；肾小球明显萎缩、玻璃样变性，肾小管也变性甚至坏死，使肾硬化程度显著增加呈颗粒性固缩肾，肾体重比也显著减少。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新