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60 grown-up male SD big mice divide into the blank control group, the model group, the Nimmo horizontal group, XXX oral large, medium and small monitoring team stochastically.

目的:探讨XXX口服液对急性脑出血大鼠的神经病态评分、血脑屏障指数及脑组织中神经元特异性烯醇化酶、肿瘤坏死因子表达的影响。

The niter benzene is even is treats the recovery period fluorine acetamide to be poisoned patient's effective method, may enable his/her the brain harm to obtain the as soon as possible repair, improves the brain function, makes the unusual electroencephalogram to restore normal or the change for the better as soon as possible.

硝苯地平是治疗恢复期氟乙酰胺中毒患者的有效手段,可使其脑损害得到尽快修复,改善脑功能,使异常的脑电图尽早恢复正常或好转。

After the use niter benzene even treatment and the treatment all around, separately makes the electroencephalogram inspection to two groups of case of illness.results: after the use niter benzene even treatment all around, the treatment group electroencephalogram restores quickly to the comparison group, exceptionally leads obviously to be lower than the comparison group.conclusions: the niter benzene is even is treats the recovery period fluorine acetamide to be poisoned patient's effective method, may enable his/her the brain harm to obtain the as soon as possible repair, improves the brain function, makes the unusual electroencephalogram to restore normal or the change for the better as soon as possible.

在使用硝苯地平治疗前和治疗4周后,分别对两组病例均作脑电图检查。结果:使用硝苯地平治疗4周后,治疗组脑电图恢复快于对照组,异常率明显低于对照组。结论:硝苯地平是治疗恢复期氟乙酰胺中毒患者的有效手段,可使其脑损害得到尽快修复,改善脑功能,使异常的脑电图尽早恢复正常或好转。

To restrain the activation of NF-κB and ICAM-1 and to lessen the inflammation might be the protective mechanism of NYA.

抑制NF-κB及ICAM-1的活性,改善炎症反应,可能是脑溢安治疗脑出血的保护机制。

NYA can up-regulate the BDNF、GDNF protein and mRNA expression in brain of ICH injury rats.

(1)脑出血损伤大鼠脑内BDNF、GDNF蛋白及mRNA的表达均增强,脑溢安能上调BDNF、GDNF蛋白及mRNA的表达水平。

The BDNF and GDNF protein expression level of NYA group were higher than model group at 1d、4d after ICH injury (P.05). To sum up, NYA could up-regulated the expression of BDNF and GDNF protein.

脑溢安组BDNF、GDNF蛋白的表达在1d、4d强于模型组,两组阳性细胞计数表明差异有显著性(P.05),提示脑溢安能上调上述两种蛋白的表达。

The corresponding change of the blood flow of the ophthalmic arteries takes place when the internal carotid artery stricture lead to acute cerebral ischemia. The Vmean, Vmax, RI, PI of the ophthalmia artery showed significant reduce, but the change of Vmin was no difference.

当颈内动脉狭窄引起脑缺血时,眼动脉与脑动脉发生相似的血流动力学改变,眼动脉的平均血流速度、最大血流速度、阻力指数、搏动指数较前均明显降低,而最小血流速度不发生明显改变。

Methods To deter mine the composition and activation of cerebroproptein hydrolysate by aminoacid analyzer,HPLC,SDS-PAG and succinate denydrogenase,to determine the therapeutic e ffectiveness of cerebrprotein hydrolysate by ordinary pressure oxytolerant exper iment and paramnesia experiment.

用氨基酸分析仪、高效液相色谱仪、SDS凝胶电泳和琥珀酸脱氢酶法测定脑蛋白水解物的组成与活性。用常压耐缺氧实验和记忆获得障碍法测定脑蛋白水解物的疗效。

Methods The cognitive impairment rat model was induced by hypodermic D-galactose injection and half fat feeder (6 weeks), the Morris water maze was used to screen the model rats, which were divided randomly into 4 groups (12 rats in each group): the model group, the hydrochloricdonepezil group (0.4 mg/kg, weight, sic passim), the low-dose Huannao Yicong Fang group (7 g crude drug/kg), the high-dose Huannao Yicong Fang group (14 g crude drug/kg), they were treated respectively by intragastric administration. Besides, a control group of 12 rats was set up, they were given tales doses of distilled water. After 4 weeks, the behavior of the rats was detected, the contents of plasma P-selectin and PAI-1 were measured by ELISA, also the hemorrheology was measured.

采用皮下注射D-半乳糖及喂饲半高脂饲料(6周)的方法造成大鼠认知功能障碍,Morris水迷宫行为学测试确定模型成功的动物,随机分成四组(每组12只:模型对照组给予等量水,盐酸多奈哌齐组(0.4mg/kg,体质量,下同),还脑益聪方低剂量组(7g生药/kg),还脑益聪方高剂量组(14g生药/kg),同时灌胃给药,并设立正常对照组,给予等量水。4周后,对大鼠行为学检测,应用酶联免疫法检测大鼠血浆P-选择素及PAI-1含量和血液流变学各项指标。

Bjectives The effects of brain trauma on levels of VIP in the plasma and pulmonary of rat and pathophsiology of VIP in acute lung injury caused by brain trauma were observed.

目的观察脑创伤对大鼠血浆和肺组织血管活性肠肽含量的影响,以及VIP在脑创伤致急性肺损伤中的意义。

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