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METHODS: Fourteen patients proved pathologically as brain abscess and 17 cystic/necrotic metastatic tumor underwent conventional MRI and DWI examinations. DWI signal and ADC value were evaluated in cerebritis stage, capsule formation stage, and evolution stage of brain abscess and compared with those of cystic/necrotic metastatic tumor. Chisquared test and t test were performed for statistic analysis.

病理及临床证实脑脓肿14例,坏死囊变脑转移瘤17例,经常规磁共振检查及弥散加权检查,在脑脓肿脑炎期、包膜期及吸收期进行弥散信号及ADC值的测量,并与坏死囊变脑转移瘤相比较,统计学分析采用χ2检验和t检验。

METHODS: Fourteen patients proved pathologically as brain abscess and 17 cystic/necrotic metastatic tumor underwent conventional MRI and DWI examinations. DWI signal and ADC value were evaluated in cerebritis stage, capsule formation stage, and evolution stage of brain abscess and compared with those of cystic/necrotic metastatic tumor.

病理及临床证实脑脓肿14例,坏死囊变脑转移瘤17例,经常规磁共振检查及弥散加权检查,在脑脓肿脑炎期、包膜期及吸收期进行弥散信号及ADC值的测量,并与坏死囊变脑转移瘤相比较,统计学分析采用χ2检验和t检验。

At present the clinical curing fundamental of acute ischemic CVD is to clean out the thrombus, drop fibrin, resist hematoblast conglomeration , protest brain and so on.

恢复缺血部位的血供确实是治疗脑缺血疾病的一个关键所在,但是缺血再灌也有可能导致脑微血管损害,出现血管源性脑出血、脑水肿,加重脑损害。

The results show that:44 out of 179 cases are of HECHDT,and 37 out of 179 cases are of death; the occurrence rate of digestive tract hemorrhage resulted from the hemorrhage of cerebral basis segment complicated by ventricle hematocele is the highest,and the sequence of the occurrence rates resulted from other position is subarchnoid cavity,brainstem,cerebral lobes,cerebellum,and within cerebral basis segment's hemorrhage; the encephalorrhagia complicated by the hemorrhage of digestive tract is mainly related to the factors of ventricular hematocele,center-line structure shift,hematoma quantity etc,and its case mortality is relatively high.

结果表明:179例中并发消化道出血44例(24.6%),死亡37例(20.7%);消化道出血发生率以脑基底节区出血并脑室积血为最高(38.9%),其次依序为蛛网膜下腔、脑干、脑叶、小脑和局限于脑基底节区出血;并发消化道出血的病死率为50%,无消化道出血的病死率为11.1%。脑出血并发消化道出血主要与出血溢入脑室、中线结构移位、血肿量大等因素有关,且病死率高。

objective to obtain the diffusion tensor maps of the normal human brain,and assess intrinstic properties of water diffusion in quantitative parameters for an anatomic analysis.methods maps of isotropic apparent diffusion coefficient and various anisotropic maps were calculated in60healthy adults from seven diffusion imagings by using single-shot echo-planar diffusion-weighted sequence.brain parenchyma anatomy was analyzed and adciso and various anisotropic index were measured.results (1)diffusion properties of different tissues and anatomic areas of normal adult human brain are different.diffusion in white matter is anisotropic;diffusion in gray matter is isotropic.

目的 获取正常人脑组织扩散张力性图像(diffusion densor imaging,dti),定量分析正常人脑组织水扩散的内在特性,进一步评价脑解剖结构。方法 60例健康正常人,应用单次激发epi-dw序列,计算出adciso图及各向异性图,分析脑实质不同区域的解剖结构,测量adciso(isotropic apparent diffusion coefficient)及各向异性指数。结果(1)脑内不同组织结构弥散特性不同,脑白质弥散表现为各向异性,而脑灰质弥散表现为各向同性。

Results:All of the cases studied,38 cases were abnormal(82.6%).Their magnetic resonance imagings manifested encephalatrophy、leukodystrophy、cerebromalacia、cerebral maldevelopment,and infections of the central nervous system.

结果:46例中,MRI异常38例(82.6%),脑萎缩、脑白质病变、脑软化灶、先天畸形、中枢神经系统感染等是脑性瘫痪常见的MRI异常表现。

Compared with CT or MRI,SPECT study can make out the location and size of infarction in the much earlier stage,and provide reliable evidence for the ultra-acute treatment of hemorrhage and infarction,or as MRI in the revealment of smaller lesion in and deep brain,so these three kinds of diagnoses method can not be substituted each other.

但对脑出血与脑梗死的鉴别不如CT对脑干及脑深部,较小病灶不如MRI显示清楚,因此三种检查方法不能互相取代。

The brain stem lesions observed on MRI were most commonly at the tegmentum of the pons (18/25, 72%) followed by the medulla oblongata (15/25, 60%), and the midbrain which includes the tegmentum, substantia nigra and superior cerebellar peduncles (11/25, 44%).

二十五例在急性期接受磁振造影检查的病童中,有十八例发现在脑干和上颈脊髓有T2高讯号病灶,病灶发现频率依序分别为:桥脑(18/25,72%),延脑(15/25,60%),中脑(包括脑盖,黑质区和上小脑脚)(11/25,44%)。

132 patients with PICH between June 1999 and June 2001 in the Tongji Hospital were included in the present study. Patients with hemorrhage secondary to traumatism, brain tumor, thrombolytic treatment, vascular malformation or with hemorrhagic infarction were excluded.

通过病史、神经系统体格检查和头部CT检查,并排除外伤性脑出血以及脑肿瘤、动静脉畸形、出血性脑梗塞、溶栓治疗等引起的继发性脑出血后,将1999年6月至2001年6月武汉同济医院住院的132例脑出血患者作为研究对象。

12H treatment group compared with 12h model group: the level of SOD, MDA of the Gardenoside group is no different with the model group; the level of the SOD of the Baical in group increase and the level of MDA is no different; the level of SOD of the Concha Margatitifera Usta is no different and the MDA of it decreased than the model; the level of SOD of the Cholic Acid group increased and the level of MDA decreased; the level of SOD of the Hefang Group increased and the level of MDA of it decreased than the model group.

考虑nNos可能只是参与缺血早期的神经毒性作用。到缺血24小时这一时程已经减低或耗竭。大鼠局灶性脑缺血12小时模型组缺血脑组织P53光密度值含量较正常组明显增高(p<0.01)。珍珠母治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低。胆酸治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低(p<0.05)。栀子苷治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低(p<0.05)。

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