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The suboccipital retrosigmoid approach was used on 10 adult head specimens which were fixed and perfused with color silicon, the neurovascular structures and their relationship in cere- bellopontine angles were observed under the operative microscope and endoscope.

选择经10%福尔马林充分固定,血管内灌注混有红、蓝染料的乳胶,不分性别的成人尸头10具,模拟目前临床上最长使用的枕下乙状窦后入路,在手术显微镜和神经内窥镜下,观察小脑桥脑角内的神经血管结构,确认这些神经血管的走行及其之间的解剖关系。

In the brain of adult rat, the positive immunohistochemical product of lSL-l (ISL-l-positive) was mainly located in the neuronal nucleus and found in discrete regions except to brain cortex, such as the Purkinje cell layer and the granular cell layer of cerebellum, the granular cell layer and the pyramidal cell layer of hippocampus, the mitral cell layer, the internal and external plexiform layer, the granular cell layer and the granular cell layer of olfactory bulb and so on, and several nuclei of the hypothalamus, midbrain and pons, such as claustrum, anterior olfactory nucleus, accumbens nucleus, caudate-ptamen, pallidum, substantia nigra, striatum, islands of Callaje, mammillary nucleus, anterior pretactal nucleus, habenular nucleus, amygdaloid nucleus, cuneate nucleus, rubral nucleus, gigantocellular reticular nucleus and so on.

在正常成年大鼠脑中,同源框基因islet-1表达产物(ISL-1)免疫组织化学阳性物质广泛分布于除大脑皮层外的神经细胞的细胞核内,ISL-1阳性神经元密集分布于小脑Purkinje细胞层和颗粒细胞层、海马的颗粒细胞层和锥体细胞层、嗅球的内丛层、外丛层、颗粒细胞层及僧帽细胞层等,另外在丘脑、中脑和桥脑的一些重要神经元核团均有分布,如,屏状核、前嗅核、伏核、尾壳核、苍白球、黑质、纹状体、Calleja岛、乳头体核、前顶盖前核、缰核、杏仁核、楔束核、红核网状巨细胞核等。

Million interhemispheric nerve fibers, the George Washington Bridge between the left and right side of the brain.

2亿个在脑半球之间的神经元,连接左右脑的华盛顿桥,可是很精致/脆弱的。

The anatomic and adjoining structures of the cerebellopontine angle are so complexed and important that they have large clinic and practical value to know better anatomic realationship in the area and to identify and protect the nerves and blood vessels during operation.

小脑桥脑角(The cerebellopontin angle,CPA)的解剖结构复杂,周围毗邻结构重要,所以充分了解该区域结构之间的显微解剖关系对于术中准确辨认和保护神经、血管具有重要的临床价值。

These anatomic study will help the neurosurgeon to correctly localize the facial and cochlear nerve during operations and to result in low morality and more higher anatomic and functional protection of the facial and cochleare nerve.

小脑桥脑角区神经血管差异较大,上述的解剖结果为外科手术提供了显微解剖学基础,对于术中面神经,位听神经定位,降低手术死亡率,提高面神经,位听神经的解剖及功能保存率有重要的意义。

Following brain stem injury,the number of GFAP-positive astrocytes in cerebral cortex and pervent-ricular area,dorsomedial and ventro-medial pafts of midbrain at 30 min antemortem,and in periventricular area,dorsomedial part of pens,dorso-medial and ventro-medial part of medulla oblongata at 60 min antemortem.

采取针刺法造成实验大白鼠脑干损伤,用免疫组织化学LSAB法检测大脑、中脑、桥脑及延髓等不同部位脑组织中胶质原纤维酸性蛋白的改变。结果发现,生前损伤30min,大脑顶部灰质及中脑腹例中央部的GFAP阳性星形胶质细胞数目增多;生前损伤60min,除大脑顶部灰质及中脑腹侧中央部外。

Objective: To analyze the clinical features and prognosis of central pontine myelinolysis in order to improve the diagnosis accuracy and recovery rate.

目的:探讨桥脑中央髓鞘溶解症的临床特征及预后,提高其疾病的确诊率和治愈率。

Purpose: To report a case of One and a halt syndrome related to sudden hemorrhage of the pontine area.

目的:报告一个因桥脑出血而造成罕见的1又1/2症候群及相关神经学症状的病例。

Human brain bridging veins may be the key point of brain vein blood outflow volume because of existing of "outflow cuff segment": ICP increased, outflow resistance increased, outflow volume reduced, then caused the aggravatation of vein blood deposition in vein bed. Such a sequent procedure formed an infernal circle: ICP increase-vein outflow reduce-vein blood deposition-ICP increase all the better.

该部分研究结果发现,由于流出口狭部的存在,人脑桥静脉是脑静脉血液流出被动调节机制的关键环节,颅内压增高,流出阻力增加,流出量减少,进而又加重了血液在静脉血管床的淤积,形成颅内压增高-静脉流出量减少-静脉血淤积-颅内压进一步增高的恶性循环。

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