脑样的

Objective To explore the effect of hyperphosphorylated tau protein on the formation of brain amyloid.

目的 研究tau蛋白过度磷酸化对脑淀粉样蛋白生成的影响。

Results (1) 6 cases of Tuberous Sclerosis. Diffused subependymal nodular calcification lesions were found in all cases on unenhenced CT. 4 patients are 2 pairs of mother/child relationship. Both of the two mothers are found to suffer from renal angiomyolipoma.(2)1 case of neurofibromatosis showed abnormal spinal canal: scoliosis of thoracic and lumbar spine, concave change of vertebral posterior border. Bilateral renal hypogenesis was found in this patient. Diffused hyper-density lesions were found in kidney and fatty accumulation was found in back skin.(3)6 cases of Sturge-Weber syndrome. On unenhenced CT, curving and strip-shaped calcifications were found along the parietal and occipital gyrus.

结果 ①结节性硬化6例，所有病例CT平扫见两侧脑室室管膜下多发小结节状高密度钙化灶，其中4例为两对母子关系，并见两位母亲合并有肾脏错构瘤，；②神经纤维瘤病1例，MRI表现为椎管异常，胸腰段脊柱侧弯，椎体后缘呈明显的切凹改变；伴有双肾发育不良，CT示肾内多个高密度影，背部皮肤多量脂肪堆积，③脑颜面血管瘤综合征6例， CT可见顶枕部沿脑回分布的弯曲的条状高密度钙化，部分延伸致侧脑室内，增强后见病灶内有扭曲的条状和结节状明显强化的血管影；④小脑血管瘤病4例，影像学表现为小脑内大囊、小结节样占位性病变。

Methods: Rat MSC was isolated and purified in vitro,labelled by Hoechst33342, stereotaxis imbed into CA4 of rat hippocampus.

近来研究发现，MSC可以分化为神经元样细胞、胶质样细胞等［1］，植入体内后对脑和脊髓的损伤性疾病有治疗作用［2］，为MSC替代治疗神经系统疾病提供了实验基础。

Objective To study the changes of expression of α-SM-actin in some cerebral arterioles with different severities of Aβ deposit in the cases of cerebral amyloid angiopathy.

目的 脑淀粉样血管病患者不同病变程度脑小动脉中α-平滑肌肌动蛋白表迭变化的对比。

A novel method of EEG signals compression representation and epileptiform spikes recognition based on wavelet neural network and its algorithm is presented.

在对小波神经网络及其算法研究的基础上，提出了一种对脑电信号压缩表达和痫样脑电棘波识别的新方法。

A novel method of EEG signals compression representation and epileptiform spikes recognition based on wavelet neural network and its algorithm is presented.

在对小波便秘神经网络及其算法研究的基础上，提出了一种对脑电信号压缩表达和痫样脑电棘波识别的新方法。

Objective To understand synchronized relation between rhythms at different function state and states shifted during epileptiform discharges.

目的 了解痫样放电不同阶段脑电信号各节律的同步关系及其在不同脑功能状态间转换时的变化。

People often occur in elderly vascular sclerosis, high blood pressure sustained more easily lead to cerebral arteriosclerosis, vessel wall hyalinization appears fat, thus weakening the strength of the vessel wall, together with the blood of the structure of the wall is relatively weak, the middle vascular myocytes less, the lack of external elastic layer developed arterial adventitia easily occurred in the brain artery wall limitations small expansion, the formation of micro-miliary aneurysm.

人到老年血管常会发生硬化，持续的高血压更容易导致脑动脉硬化，血管壁出现脂肪玻璃样变，从而削弱血管壁的强度，加上脑血管壁的结构比较薄弱，血管中层肌细胞少，缺乏外弹力层，动脉外膜不发达，容易造成脑内小动脉壁发生局限性扩张，形成粟粒性微动脉瘤。

We report a 36-year-old man with MELAS in whom a 5-month course of high-dose oral idebenone, a derivative of coenzyme Q10, increased markedly cerebral metabolic ratio of oxygen and oxygen extraction fraction without increased cerebral blood flow with PET.

我们报告了一例36岁患MELAS（线粒体脑肌病伴高乳酸血症和卒中样发作）的患者，在口服一种辅酶Q10衍生物艾地苯醌后，显著地增加了氧气和氧提取部分的比例而同时不增加患PET症的患者的脑血流量。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后，血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少，Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少，血小板聚集程度及红细胞聚集指数显著上升，病理切片显示胸主动脉内皮细胞破坏明显，脑心肾组织内的血管进一步增厚甚至几乎阻塞，导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR，脑体重比显著升高；心肌内出现明显的缺血梗塞疤痕灶，心体重比显著升高；肾小球明显萎缩、玻璃样变性，肾小管也变性甚至坏死，使肾硬化程度显著增加呈颗粒性固缩肾，肾体重比也显著减少。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。