脑损伤

Methods: On the basis of middle cerebral artery occlusion model in rats, free radicals were detected in hyperglycemic rats and normoglycemics.

建立大鼠左大脑中动脉梗死(Middle Cerebral Artery Occlusion，MCAO)模型，在证实高血糖可加重局灶性脑缺血损伤的基础上，检测正常和高血糖脑缺血后不同时间的自由基水平。

Results The exoression of MMP-9 was significantly increased in hyperglycemic groups after irrigating 24h,48h post 2h ischemia.

高血糖可诱导脑缺血再灌注后脑组织内的MMP-9 表达，增加血脑屏障的通透性，从而加重脑组织的损伤。

Objective To determine the effects of diazoxide on a model of brain injury induced by deep hypothermic cerebral ischemia/reperfusion.

目的 探讨二氮嗪预处理对幼龄大鼠深低温脑缺血／再灌注损伤脑保护作用。

Cerebral malacia in 10.7%, developmental abnormalities in 10.5%, perinatal brain injury in 8.1%, mesial temporal sclerosis in 5.4%, brain tumor in 4.9%, and the other in 15.0%.

进一步研究表明20岁以下的患者以脑发良不良、围产期损伤、颅内感染、海马硬化多见，而20岁以上患者以颅内感染、脑外伤、脑血管病多见。

objectiveto investigate the effect of myricetin dispersible tablets on experimental cerebral ischemia-reperfusion injury in rats and thrombosis formation.methodsexperimental cerebral ischemia-reperfusion injury model was induced by ligation bilateral common carotid arteries. the protective effect of myricetin dispersible tablets was observed by detecting the content of cerebral water, sod and mao activities,mda and la contents.

方法采用双侧颈总动脉结扎法制备大鼠实验性全脑缺血再灌注损伤模型，通过测定大鼠脑含水量，超氧化物歧化酶、单胺氧化酶的活性和丙二醛、乳酸的含量，观察杨梅素分散片对大鼠实验性脑缺血的影响；采用体内静脉血栓形成法，观察杨梅素分散片对体内静脉血栓形成的影响；并研究其对血小板聚集的影响。

MethodsExperimental cerebral ischemia-reperfusion injury model was induced by ligation bilateral common carotid arteries. The protective effect of myricetin dispersible tablets was observed by detecting the content of cerebral water, SOD and MAO activities,MDA and LA contents.

方法采用双侧颈总动脉结扎法制备大鼠实验性全脑缺血再灌注损伤模型，通过测定大鼠脑含水量，超氧化物歧化酶、单胺氧化酶的活性和丙二醛、乳酸的含量，观察杨梅素分散片对大鼠实验性脑缺血的影响；采用体内静脉血栓形成法，观察杨梅素分散片对体内静脉血栓形成的影响；并研究其对血小板聚集的影响。

Methods Brain microvascular endothelial cells and neuroglial cells of newborn rats were cultured in vitro, and treated with 1,2-dichloroethane at a dose of 0 μl/ml, 5 μl/ml, 10 μl/ml or 20 μl/ml.

方法］在体外建立了血脑屏障细胞模型，并从形态学上观察1，2-二氯乙烷对血脑屏障细胞的损伤作用。

The imbalances of SS-GH axis regulation, the regulator disorders of GluR, GluR affinity and Glu, SS-MTL axis, SS- Gastrin axis etc. showed obvious perturbations of internal circumstance in CNS and local Gastroenteral tissues. It is one of the important causes that intracerebral hemorrhage may exist extensively in range and seriously in degree, and may evoke irreversible neuronic damage.

脑出血过程中SS—GH轴调控异常，GluR及其亲合力与Glu的调节障碍以及SS—MTL，SS-Gastrin的相互调节失衡，充分表明中枢与胃肠局部均存在明显的内环境紊乱，是脑出血损伤范围广，程度严重，促使NC不可逆性损害的重要原因之一。

It is recently reported that SS and SS mRNA may contribute to the formation of neuronic edema surrounding an intracerebral hematoma, inhibit the assembling of cAMP in neurons, promote regulatory disorders of Growth Hormone , and thus aggravated neuronic injury in intracerebral hemorrhage.

SS（Somatostatin，SS）及其mRNA在CNS及胃肠胰均有广泛分布，是传递脑与胃肠信息联系的重要递质，进年来证明，它们在CNS通过促进血肿周边NC水肿，抑制NC cAMP的积聚，并使生长激素（Growth Hormone，GH）调控失衡加重脑出血对CNS NC的损伤。

Qingnao drop pilula can alleciate histomorphology lesion of hippocampus when occurring acute multi-infarction, to turn slower MARCKS mRNA expression, may play a neuroprotective effect role through accommodating PKC-MARCKS signal transduction system.

清脑滴丸可以减轻急性脑缺血时海马组织损伤，下调MARCKS mRNA的过高表达，其机制可能是通过调节PKC-MARCKS信号转导系统而起到神经保护作用。

If you are committed to an education career, then the Master of Arts in Education from Ashford University is for you.

如果你是致力于教育事业，那么，艺术教育硕士学位阿什福德大学是给你的。

objective:to explore the expression of survivin protein and its mrna in rectal cancer and their clinic significance.

目的：研究凋亡抑制因子survivin蛋白及其mrna在直肠癌组织中的表达及其与临床病理关系。