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The purpose of this aticle is to study the CT signs in diffuse axonal injuryof acute brain injury.

目的:在急性脑外伤患者的CT片研究脑弥漫性轴索损伤的CT征象,目的是为DAI的诊断提供影像学依据。

It is indicated that the protective mechanism is related to the preservation of vascular endothelial cell function and intact basilemma, improvement of microcirculation and reduction of cerebral edema.

提示冰片与川芎配伍可通过保护血管内皮细胞功能、基膜的完整性,改善微循环,减轻脑水肿程度,从而对脑缺血再灌注损伤起保护作用。

The right parietal cortex contusion was made with stab wound and the rat was killed at various survival time( 30min, Ih, 3h, 6h, 12h,ld, 3d, 7d, 14d, 21d). Paraffin sections(4 μ m) were cut coronally of the whole brain and stained with antibody of GFAP, the hemotoxylin eosin stain was done in the mean time.

实验组用针刺法造成大鼠右顶叶脑挫伤后,按30min,1h,3h,6h,12h,1d,3d,7d,14d,21d不同时间分批处死动物并立即取出全脑,同时颈静脉取血2ml,正常对照组不造成颅脑损伤,直接处死动物后立即取材。

Objective To compare the outcomes of standard large craniectomy with routine craniectomy in 223 severe traumatic brain injured patients.

目的 比较标准大骨瓣与常规骨瓣开颅术治疗重型颅脑损伤合并脑挫裂伤脑水肿、恶性颅内高压患者的效果。

Quick development of functional imageology brings the moment of researching on impairment recovery of epencephalic after stroke and the therapy mechanisms of acupuncture and moxibustion.

功能影像学技术的飞速发展为研究中风后脑的损伤恢复和针刺的疗效机制提供了契机,为较全面、直观、无创的观察生理、病理状态下的脑功能变化,以及针刺对脑运动功能重塑的作用位点和作用途径研究提供有力的技术支持。

Objective To examine the value of Edaravone in the treatment of vascular dementia through ethologic and pathologic changes induced by chronic cerebral ischemiaMethods Wistar rats were randomly divided into sham operated group,model group,edaravone group and duxil groupThe chronic cerebral hypoperfusion models were made by permanent bilateral occlusion of both common carotid arteriesThe memory ability and ultramicrostructure of brain tissue were observedResults The escape latencies in model group were more significantly prolonged than that in the other groups (P<005)But there was no significant difference between edaravone and duxil groupAnd pathologic changes observed by electron microscope in nerve cell of edaravone group and duxil group and model group were fairly light than that in sham operated groupEdaravone group had increased mitochondrium and frontal membranous synaptic vesicle and more productive metabolic activityConclusions Edaravone can lessen injures of hippocampal neurons loss to improve the spatial learning and memory abilitiesAnd it is proved further that edaravone can treat VD

目的 观察依达拉奉对慢性缺血致血管性痴呆大鼠行为学及形态学的影响,探讨依达拉奉在治疗VD中的应用价值。方法实验分假手术组、模型组及都可喜对照组及依达拉奉治疗组,应用双侧颈总动脉结扎方法制备慢性脑缺血大鼠痴呆模型,观察各组大鼠的记忆功能及脑组织超微结构改变。结果缺血组水迷宫表现同对照组、都可喜组及依达拉奉组相比有显著差异(P<005),依达拉奉组与都可喜组相比未见显著差异。同时电镜观察结果也发现依达拉奉组及都可喜组与模型组及假手术组相比神经细胞病理改变较轻,且依达拉奉组线粒体及前膜突触小泡增多,代谢活动较都可喜组旺盛。结论依达拉奉可能通过减轻海马神经元的损伤来改善慢性脑缺血大鼠空间学习记忆障碍,证明依达拉奉对慢性缺血致VD大鼠具有治疗作用。

Objective To evalue the protective effect of propofol against cerebral ischemia-reperfusion injury in patients with acute cerebral infarction.

目的 探讨异丙酚对急性脑梗塞患者脑缺血再灌注损伤的保护作用。

The synthetic and release of excitory amino acids are greatly increased after cerebral ischemia and the balance btween excitory amino acids and inhibitory acids are broken.

脑缺血性损伤时,脑内兴奋性氨基酸的合成、释放明显增加,兴奋性/抑制性氨基酸的动态平衡被打破。

The stress distribution widespreadly and unequivalently in brain tissue, which mainly effect by the cerebelar tentorium, cerebral falx, and unregular geometry of cranial bone .

结论脑内质点应力差值致脑组织剪应变损伤,猫颅骨不规则的几何形状、小脑幕、大脑镰结构是导致旋转暴力向脑内传递广泛而不均一的主要原因。

Chinese Medicine treatments on apoplexy has a long history with favorable curative effect,among them,acupuncture and moxibustion therapy is the important way for hemiparalysis rehabilitation,while the influence of acupuncture and moxibustion on cerebral function remodeling.

功能影像学技术的飞速发展为研究中风后脑的损伤恢复和针刺的疗效机制提供了契机,为较全面、直观、无创的观察生理、病理状态下的脑功能变化,以及针刺对脑运动功能重塑的作用位点和作用途径研究提供有力的技术支持。

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