脑损伤

Objective to explore the way of identify the size and evolving process of reversible damaged region and irreversible damaged region.

目的：对急性脑梗塞可逆性损伤区和不可逆性损伤区进行界定并观察其演变规律，为超急性期溶栓治疗的必要性及时间窗等问题提供影像学依据。

The recovery of blood circulation of ischemia semidarkness region, improvement of partly hypoxia state and prevention of more serious of impaired are key point in the stroke treatment. This experiment is designed to observe the blood vessel regeneration of ischemia injured region, and observe the variance of partly PCNA and VEGF expression. Combine with limbs functional recovery, we validate the therapeutical effect of acupuncture and investigate the possible mechanism of action.

尽早恢复缺血半暗区的血液循环，改善局部缺氧状态，防止损伤的进一步加重是脑卒中治疗过程中的重点，本实验从缺血损伤区血管再生为切入点，观察局部PCNA、VEGF表达的变化，结合肢体功能恢复情况，验证针刺的治疗作用，并探讨可能的作用机制。

At postoperative 24 hours, neurological defects were scored in five grades [0 score represent no neural impairments; 1 score: the left posterior limbs displayed decreased muscular tension and attenuated contraction reflex; 2 scores: the left posterior limbs were paralyzed, displaying obvious abduction; 3 scores: rabbit displayed obvious adductive drag with body leant to the opposite side; 4 scores: unable to walk and unconsciousness], rabbits were put to death at postoperative 48 hours, infarctional area and volume were determined and pathological changes was also observed.

术后48 h处死兔，测量梗死灶面积、体积，并制作病理切片观察损伤程度。主要观察指标：兔肢体功能状态，脑梗死灶面积和体积，病理损伤程度。结果：59只兔成功建立起梗死灶，模型成功率为98％。①神经功能缺失评分：56只兔为1或2分，有3只兔达到3分。②梗死灶平均面积为(0.465±0.012)cm2，平均体积为(0.268±0.009)cm3。

EPO was considered to be excreted only by the kidney and responsible for the proliferation, maturation, and differentiation of the precursors of the erythroid cell line incretory hormone.

在大鼠脑损伤模型中，EPO对抗损伤后炎症反应，并起到神经保护作用；在实验性自身免疫性脑脊髓炎大鼠模型和大鼠大脑中动脉梗塞模型的研究中发现，EPO可明显抑制促炎性细胞因子和趋化因子的产生，进而减轻炎症反应。

NB can make liver, brain, spleen and nephridial tissue pathology damage, to refrain theactivity of liver mixed function oxidase, induce oxidative stress, effect tissue enzymatic activity,destroy organism antioxygen defence system and function of clean up free radical, to cause proteinoxidation damage, to educe toxic action.

综上所述，NB可以造成肝、脑、脾、肾组织的病理学损伤，抑制肝内混合功能氧化酶的活性，诱导氧化应激，影响组织酶活性，破坏机体抗氧化防御系统及清除自由基功能，引起机体蛋白质氧化损伤，进而发挥其毒性作用。

The effects of Shuluo on cerebral ischemia is investigated in this dissertation which consists of three parts: injury in middle cerebral artery reperfusion rats, injury in cerebral vessels and the penetrativity of blood brain barrier.

本文将从缺血再灌注损伤、脑血管损伤和血脑屏障三个方面，阐述舒络治疗缺血性中风的作用机制，为临床合理用药提供科学依据。

APHs, TF and GnH were tested in 93 patients with TBI,who were admitted to Zhejiang Provin-cial People's Hopital from March 2006 to June 2007. Patients with primary injury in the hypothalamic and pituitary regions, as detected by CT and/or MR/examination, as well as those with tumors or immune diseases in the CNS,endocrine or urinogenital systems, were excluded. The clinical data were analyzed according to Glasgow coma scores, type and degree of injury, and whether there was any secondary cerebral injury.

随机对浙江省人民医院2006年3月至2007年6月经系列头颅CT扫描和/或MRI检查，明确无下丘脑、垂体等部位的原发损伤，且既往无中枢神经系统、内分泌和泌尿生殖系统肿瘤及免疫性疾患史的93例门急诊和住院TBI患者的APHs、TF和GnH进行测定，并按患者的GCS评分、TBI类型和损伤程度以及有无继发性脑损害等因素进行分组研究，以同期20例健康体检者作为对照组。

Methods: The cerebral cortical astrocytes and neurons of rats were cultured and the model of simulated cerebral ischemia and reperfusion was set up in vitro. The activity, survival rate, death rate of the neurons, leakage rate of lactate dehydrogenase and the activity of nitric oxide synthase of cerebral cortical neurons were measured after 18 boors of reperfusion.

分离纯化培养大鼠大脑皮质Ast和神经元，体外模拟脑缺血再灌注损伤模型，用ACM培养损伤后的神经元，测定其神经元的活性、存活率、死亡率、培养液乳酸脱氢酶的漏出率和NOS强阳性细胞的表达量。

Aim:To study the experimental methodology based on cerebral microdialysisand high performance liquid chromatography with electrochemicaldetection, make the acute rat model of Parkinsons diseasesinduced by 6-hydroxydopamine(6-OHDA), examine the effects of the generalcistanosides on the striatal extracellular levels of monoamines neurotransmittersin rat model of PD and find the possible mechanisms of the neuroprotective actionproduced by GCs.

目的：建立基于脑微透析和高效液相-电化学检测法的实验方法；制作6-羟基多巴胺(6-OHDA)损伤致急性帕金森病大鼠模型；研究肉苁蓉总苷对6-OHDA损伤致急性PD模型大鼠纹状体细胞外液中单胺类递质含量的影响，以探讨其对脑神经保护作用的可能机制。

As for harm, brain and nere damage from siler exposure is rare, but colloidal siler can cause kidney damage, stomach distress, and headaches.

至于害处，虽然银暴露对脑和神经的损伤比较罕见，但胶银能导致肾损伤、腹痛及头痛。

The X-ray diffract was used to analyze the crystal structure of the composite. Results show that after the talc was treated with blend coupling agent, the crystal structure of talc changed, and effect Intercalation phenomenon.

通过X射线衍射分析可知，用混合偶联剂对滑石粉进行预处理后，滑石粉晶体结构发生改变，产生了插层现象，使PP／滑石粉复合材料为纳米复合材料。

An authentic Maui wedding might require the services of a 'kahu', which is a Hawaiian minister.

毛伊可能需要一个真实婚礼服务'kahu'，这是夏威夷部长。