脑损伤

Results The expression of FOS,JUN,bFGF,and VEGF protein of the cere...

结果正常小鼠脑组织FOS、JUN、bFGF、VEGF低水平表达，B组略强。A组脑组织FOS和JUN的表达具有时程的一致性，创伤性脑损伤后3 h达到高峰，12 h以后降至对照水平；bFGF与VEGF分别于创伤性脑损伤后12 h、24 h达到高峰，72 h降至对照水平。

The nestin in the cortex, hippocampus and extraventricular zone was significantly increased after HIBD, peaking at 7 days.

外源性bFGF可以明显增加新生大鼠缺氧缺血脑损伤后nestin蛋白表达，在缺氧缺血脑损伤后的神经元再生与修复中发挥一定保护作用。

Aim To investigate the relationship between the changes of N-methyl-D-aspartate receptor activity on cerebral cortex and brain edema after brain injury in the rats.Methods The brain injury model was made by a free-falling body.

目的 脑损伤后释放的谷氨酸通过其受体，主要是N-甲基-D-天门冬氨酸受体而发挥神经元兴奋毒作用；通过对脑损伤后不同时期伤侧大脑皮质NMDA受体活性和含水量的测定，探讨它们之间的关系。

METHODS: Ninety cases of brain injury were enrolled from Beijing Enyu Baby Brain Development Gradate Center and then received transfer treatment including alternative diet, environment analysis and muscular response for the detection of hypersensitive food and environment and for the avoidance of sensitive material by NAET disallergization. The treatment duration ranged from several days to several months.

选择自1999年北京各大医院明确诊断、并经过一段时间治疗、因疗效不佳转诊而来的脑损伤儿童90例，在北京恩宇脑潜能开发研究中心采用轮换饮食、环境分析以及肌肉应答测试法检测过敏的食物和环境因素、禁止接触过敏物质以及NAE下脱敏法对脑损伤儿童进行训练，时间数日至数月。

If the patient survives the ictus, the resulting hematoma within brain parenchyma triggers a series of events leading to severe neurological deficits, even causes long-term brain damage, such as cerebral palsy, mental retardation and epilepsy for newborns.

如患者能幸存，也常因脑水肿及脑实质内血肿触发的一系列神经生物反应而导致严重神经系统损伤，尤其是新生儿，可遗留永久性的脑损伤，如脑瘫、智力低下、癫痫等。

Objective To investigate the protective effect of ligustrazine on brain injury.Methods The effects of ligustrazine on breath time of head decollated mice and survival time of hypoxic mice induced by sodium nitrite were observed and neurological score and infarct area in the middle cerebral artery occlusion rats were measured.

目的 研究川芎嗪对脑损伤的保护作用方法采用小鼠断头法、亚硝酸钠(NaNO2)致死法、鼠大脑中动脉栓塞法，通过观察断头喘息时间、亚硝酸钠致死时间、脑缺血行评分、脑缺血面积，明确川芎嗪对脑损伤的保护作用。

Transplantation of BMSCs in neonate rats at 24 hours after HIBD has the maximal long-lasting ethological improvement, which is induced by brain damage, and the mechanism may be that early transplantation with BMSCs reduces effectively neuron necrosis and apoptosis, and is helpful for the migration and differentiation of BMSCs.

新生大鼠缺氧缺血性脑损伤后24 h接受骨髓基质细胞移植可最大程度改善脑损伤所导致的远期行为学障碍，其机制可能与早期移植可有效减轻神经元的坏死、凋亡，且有利于骨髓基质细胞的迁移、分化有关。关键词：骨髓基质细胞；细胞移植；缺氧；缺血；脑；新生大鼠

Outcome:(1) Acute ischemic damage may induce the expression of c-fos protein in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia. And the expression level of c-fos can be up-regulated by putting blood of 12 hand Jing Points. So we think that treated by this therapy can rise the irritability of brain to resist the development of ischemia and enhance the ability to plerosis.(2) Acute ischemic damage may induce the expression of HspVO in Cerebral Cortex quickly. Also, the expression increases by the ischemia time delay. It may hint that ischemia injury can rise the ability of nerve cells to tolerate ischemia and anoxia.

三 结果(1)急性缺血性脑损伤可快速诱导c-fos蛋白在皮层缺血区脑组织的表达，其表达有随缺血时间延长而逐渐增多的趋势，提示脑的缺血性损伤可应激性地增强神经细胞对缺血、缺氧的耐受和适应能力，而应用井穴放血的干预治疗可明显上调缺血区皮层脑组织c-fos的表达水平，进一步增强脑组织对抗缺血性损伤的应激能力，抵抗缺血性脑损害的进一步发展。

Objective To study the MR findings and its relationship with clinical manifestions of cerebral palsy caused by hypoxic-ischemic brain damage.The pathological mechanisms of MR findings were also explored.Methods The MR findings of14patients with cerebral palsy caused by hypoxic-ischemic damage were studied retrospectively and correlated with clinical findings.All those patients underwent MRI.Cerebral cortex and subcortical white matter,deep white matter,basal regions and thalami,and ventricles and subarachnoid space were observed on T1WI and T2WI.

目的 通过分析14例缺氧缺血性脑损伤所致脑瘫的MR成像特点及临床表现，讨论了该病的MRI表现与临床表现的相关性，以及MRI表现的病理损伤机制方法对14例缺氧缺血性脑损伤所致脑瘫患儿行MR检查，在T1WI及T2WI上对脑皮层及皮层下白质、深部白质、基底节、丘脑、以及脑室和蛛网膜下腔等部位进行观察。

It is co ncluded that the determinations of CPK,LDH and GOT in CSF can be used as an earl y diagnostic index following acute head injury ,and there is an important value for ass essing the severity of brain damage and the prognosis of patients with acute hea d injury.

故提示脑外伤后早期CSF CPK、L DH和 GOT活性可作为急性颅脑损伤诊断的辅助指标，并对急性颅脑损伤脑损伤程度和患者预后的判断有一定参考价值。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。