脑室

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p＜0.05/p＞0.05),sod was lower than model group(p＜0.001) and was higher than control group(p＜0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响，探讨其治疗阿尔茨海默病(alzheimer disease，ad)的作用机制。方法用冈田酸(okadaic acid，oa)注射大鼠侧脑室造模，测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p＜0.001)，高于对照组(p＜0.05)；sod高于模型组(p＜0.001)和对照组(p＜0.05)；mda低于模型组(p＜0.001)，高于对照组(p＜0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性，降低mda蓄积和tau蛋白生成，具有防治阿尔茨海默病的作用。

METHODS: We measured the change in isoflurane MAC caused by intrathecal infusion of various concentrations of veratridine into the lumbothoracic subarachnoid space of rats.

我们测量大鼠在不同浓度藜芦定注入蛛网膜下腔所引起的异氟烷 MAC 值的改变并与侧脑室灌注所得的结果进行比较。

Intraventricular infusion of 1.6 and 6.4 microM veratridine did not alter MAC. Rats given 25 microM died.

脑室注入1.6和6.4 pg ／ ml 的浓度不改变 MAC 值，给与大鼠25 pg ／ ml 则大鼠死亡。

Rats ,in the sham-operation group were exposed of bilateral foramen alares and carotid artery only without occluding the vessels.

各组大鼠在麻醉状态下钻开颅骨，于前囟后1.2mm、左旁1.5—nm处用微量加样器进针3.5mm穿刺脑室。

Objective The experiment studied the effects of acetylcholine and M-receptor agonist pilocarpine on the electric activities of the pain-related neurons in the locus ceruleus of normal rats,in order to further study the role and the interaction of ACh and LC in the modulation in the algetic sense.

目的 本实验观察大鼠侧脑室内加入外源性乙酰胆碱后，蓝斑核（Locus ceruleus，LC）痛反应神经元的电变化，以及M受体激动剂毛果芸香碱的激动效应，进一步研究ACh和LC在痛觉调制中的作用及其相互关系。

Results Abnormal rate of brain CT was 59.3%, including expansion of ventricles of brain, atrophy of cortex, cerebromalacia; abnormal rate of EEG was 72.2%, including low voltage, allorhythmia of slow wave, deletion of sleep-spindle wave and attack wave.

结果脑CT异常率为59.3％，主要表现为脑室扩大、皮质萎缩、脑软化；脑电图异常率为72.2％，多表现为低电压、慢波节律异常、睡眠纺锤波缺失及发作波。

Methods Injecting betaamyloid 1-40 and aluminum into the lateral cerebral ventricle of SD male rats, and at the first time, 10ng TGF β1 was injected into the anterodorsal nucleus of thalamus simultaneously.

SD雄性大鼠侧脑室内连续注入β淀粉样蛋白1-40(Aβ1-40)和1%氯化铝溶液，首次注射时注入重组人类转化生长因子β1。

This topic intends to set up the animal model of apositia with the function of central inhibition to investigate the pharmacological effect of Shanzha Maiya granula and research the functional mechanism of the Chinese medicines for invigorating spleen to promote digestion in view of braingut petide-appestat.

CLAIRE报道LP50μg/kg单独腹腔注射可以降低大鼠进食量，LP 50μg/kg和8～16μg/kgCCK联合腹腔注射效果更佳，两者联合腹腔注射后与LP单独腹腔注射后大鼠食量比较差异有统计学意义，Scott等报道第三脑室注射LP 7μg/kg和腹腔注射CCK 2μg/kg都有降低食欲的作用。

After the termination of the model,kill the mouse,detect NPY and then see the content of NPY in the Hypothalamus of the mouse significantly lower.3.8g/kg(it is valid dose proved by pharmacodynamic experiment,about 9 times of human dose) of Shanzha Maiya granula and 13.6g/kg(15 times of human dose) of Decoction of Xiangsha six Mild Drugs can play a certain role in treating the animal model of child apositia resulting from leptin,fail to increase the animal\'s food-intake,but can increase its weight to some extent,Decoction of Xiangsha six Mild Drugs can increase the content of NPY in the Hypothalamus of the mouse.4.set up quality standard of qualitatively and quantitatively detecting Shanzha Maiya granula:detecting the content of aurantiamarin as a main component of Chenpi in Shanzha Maiya granula through the method of high performance liquid phase,qualitatively identifying Shanzha,Maiya,Chenpi through the method of plate chromatography.

造模结束处死大鼠，放射免疫法检测NPY，结果造模大鼠下丘脑NPY含量显著降低(正常组下丘脑NPY平均含量为22.2ng/ml，模型组下丘脑NPY平均含量为14.8ng/ml，P＜0.05)。3。山楂麦芽颗粒8g/kg(药效学实验有效剂量，临床用量的9倍)和香砂六君子汤13.6g/kg(临床用量的15倍)对侧脑室注射瘦素致厌食症大鼠有一定治疗作用，虽没有提高动物进食量，但在一定程度提高动物体重，其中香砂六君子汤能提高大鼠下丘脑NPY含量(模型组下丘脑NPY平均含量为14.8ng/mL，香砂六君子汤组NPY平均含量为20.3ng/mL，P＜0.05)。4。

Methods: The interhemispheric fissure width,cerebral transverse diameter,width of anterior horn of lateral ventricle,bifrontal index,minimal thickness of medial temporal lobe,interuncal distance,hippocampal height,width of the choroid fissure and width of the temporal horn of lateral ventricle were measured by MRI in 22 patients with mild AD and 20 normal senile subjects subjects respectively.

分别对22例轻度痴呆的AD患者和20例正常老年人进行纵裂宽度，大脑横径，侧脑室额角宽度，双额指数，中颞叶最小厚度，钩回间距，海马高度，脉络膜裂宽度和颞角宽度等指标测量。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。