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The contents of Ca2+, CaM in blood and brain tissue were measured by atonic absorption spectrometry and radioimmunoassay.

颅脑损伤后神经元和神经胶质细胞膜系统的钙通道开放、细胞内钙超载、钙调蛋白激活,是导致继发性脑损害、脑水肿发生的关键[1]。

High performance liquid chromatography and Griess diazotization reaction were employed to determine the levels of Hcy and NO in the plasma and the correlation between Hcy and NO was analyzed.

分别采用高效液相色谱法和Griess重氮化反应法检测62例急性脑梗死患者(起病24 h内)血浆Hcy及NO水平,分析两者的相关性及其与急性脑梗死的关系。

Methods 62 patients with acute cerebral infarction (within 24 hours) were enrolled. High performance liquid chromatography and Griess diazotization reaction were employed to determine the levels of Hcy and NO in the plasma and the correlation between Hcy and NO was analyzed.

分别采用高效液相色谱法和Griess重氮化反应法检测62例急性脑梗死患者(起病24 h内)血浆Hcy及NO水平,分析两者的相关性及其与急性脑梗死的关系。

The results showed that the activation ability value of the elite fencing athletes brain ability of infor oration processing was much higher than that of the normal people, which meant the brain could deal with more information and have more methods of information processing. The superior unilateral brain regions of information processing were the left forebrain and right epencephalon, which were the best match of both- side brain. Female athlete moods were more stable than the male athlete;besides, they were more active, having more powerful logic memory, and more rational thoughts. Among the parameter of FFQG, marginal modulus reflected the consumption of information processing which was related with the fencing athlete athletic for m. T his, the low er the modulus w as, the better w as the athletic for m. T he fencing athlete with good marginal modulus was 6z.4%.w ith the nor oral being 3 }.6%.which indicated that the efficiency of Chinese fencing athlete brain ability of information processing was rather high.

结果表明,优秀击剑运动员大脑处理信息的能力与普通人相比,激活能力总值显著较高,提示优秀击剑运动员大脑处理信息的量更大,处理信息的方式更多;击剑运动员大脑处理信息的优势单脑区为左前脑和右后脑,左前右后脑是优秀击剑运动员双侧脑的最佳匹配;男女运动员在大脑左颞区优秀图形的差异显著,提示女运动员比男运动员有更稳定的情绪,更高的内驱力,更强的逻辑记忆和理性思维能力;击剑运动员优势图形中的特征图形为内方型和隧道型,非优势图形中的特征图形为逃逸型和奇异型;脑象图的技术参数中,边缘系数反映大脑处理信息的耗能量,它与击剑运动员的竞技状态呈较高的负相关,即边缘系数越低,运动员在竞技比赛中的发挥越好;击剑运动员边缘系数优秀型占总人数的62.4%,一般型占总人数的37.6%,提示我国优秀击剑运动员大脑处理信息的效率很高。

NYA can up-regulate the BDNF、GDNF protein and mRNA expression in brain of ICH injury rats.

(1)脑出血损伤大鼠脑内BDNF、GDNF蛋白及mRNA的表达均增强,脑溢安能上调BDNF、GDNF蛋白及mRNA的表达水平。

Result: Immunohistochemic results indicate that after HBO treatment, the expression of CytC and Bax in the neuronal cytoplasm decline significantly ( P.05) except in the time of 72 hours after TBI; the Bcl-2 expression is up-regulated significantly(p.05) after TBI. The images of electromicroscope indicate that before 24hr after TBI, mitochondria of control groups become more swoln even fracted and the matrixes become vaguer than those of being treated with HBO.

郑州大学2004年硕士研究生毕要论文高压氧对大民实脸性脑顶伤后神经细胞内cytochr她eC,Bol一2以及Bax表达的影响结果:(1)对于致伤后的脑组织切片染色发现,相同时间段内(3,6,12,24小时)实验组神经细胞内CytC阳性表达明显低于对照组(P.05),而72小时以后无明显差异;Bel一2阳性表达于3,6,12,24,72小时时明显高于对照组(P.05),Bax阳性表达于3,6,12,24小时时明显低于对照组,72小时时无明显差异。

The FosB/△FosB positive staining was detected in nucleus accumbens septum, tuberculum olfactorium and dorsal caudate putamen, without little cFos positive staining. The results indicate the expression of cFos and FosB/△FosB display the differences in area and intensity, and the area intensively expressing FosB/△FosB is more nearly coincide with the area related to schizophrenia. So FosB/△FosB is a better mark to research the pathogenesis of schizophrenia.

同时大量研究证明,动物模型的行为及生理变化与中枢神经系统神经元的病理变化有关,因此,利用即早基因反应的灵敏性、功能多样性、检测方便性等,应用免疫组织化学的方法对模型小鼠脑内cFos和FosB/△FosB蛋白的表达进行检测,通过确定不同脑区cFos和FosB/△FosB蛋白的表达,来研究哪些脑区或神经元参与了反应,从而发现精神分裂症在脑区内所涉及的解剖结构,有助于对精神分裂症发病机制的认识。

In infarction patients group,DTI can early detect some small infarction lesions in white matter. With the pathophysiological evolution of the disease, FA and ADCAV changes regularly. In hyper-acute stroke, FA of lesions have no consistent change, appreciably elevated or decreased. In acute, sub-acute and chronic stages of cerebral infarction, FA of lesions unrecovered declined.

在脑梗死患组DTI能早期发现较小的白质内梗死灶,脑梗死后脑组织FA值、ADCAV值随病理生理演变呈一定规律性变化,病侧FA值在超急性期较对侧无一致性变化,可轻度升高或者轻度降低,随后(急性期、亚急性期、慢性期)呈不可复性减低趋势。

Results In all patients, acute SAH was clearly demonstrated as an area with signal intensity that was higher compared to that of the normal cerebrospinal fluid in the sulci and cisternae at FLAIR imaging.

结果 磁共振快速FLAIR序列能很好地显示所有病例的急性蛛网膜下腔出血,表现为脑池、脑沟内高信号影。

These implied that CCK synthesis in somas of the PVN and the releasing in terminals of the ME during scalding stress were increased.The emergence of CCK-containing CSF-CNs might provide their secretory products a new pathway to cerebrospinal fluid after scald and the CCK,through the CSF pathway,might involve scald stress by modulating the metabolism and activity of the adjacent peptidergic system controlling the pituitary.

为此,本实验用免疫细胞化学和显微图像分析技术研究烫伤大鼠PVN和第三脑室室管膜内CSF-CNs中CCK含量的变化,旨在探讨PVN中CCK是否参与烫伤应激反应,并为CSF-CNs在应激状态下如何平衡脑-脑脊液神经体液回路提供形态学依据。

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