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Results (1) 6 cases of Tuberous Sclerosis. Diffused subependymal nodular calcification lesions were found in all cases on unenhenced CT. 4 patients are 2 pairs of mother/child relationship. Both of the two mothers are found to suffer from renal angiomyolipoma.(2)1 case of neurofibromatosis showed abnormal spinal canal: scoliosis of thoracic and lumbar spine, concave change of vertebral posterior border. Bilateral renal hypogenesis was found in this patient. Diffused hyper-density lesions were found in kidney and fatty accumulation was found in back skin.(3)6 cases of Sturge-Weber syndrome. On unenhenced CT, curving and strip-shaped calcifications were found along the parietal and occipital gyrus.

结果 ①结节性硬化6例,所有病例CT平扫见两侧脑室室管膜下多发小结节状高密度钙化灶,其中4例为两对母子关系,并见两位母亲合并有肾脏错构瘤,;②神经纤维瘤病1例,MRI表现为椎管异常,胸腰段脊柱侧弯,椎体后缘呈明显的切凹改变;伴有双肾发育不良,CT示肾内多个高密度影,背部皮肤多量脂肪堆积,③脑颜面血管瘤综合征6例, CT可见顶枕部沿脑回分布的弯曲的条状高密度钙化,部分延伸致侧脑室内,增强后见病灶内有扭曲的条状和结节状明显强化的血管影;④小脑血管瘤病4例,影像学表现为小脑内大囊、小结节样占位性病变。

Objective To compare the effect and safety of intra-arterial thrombolysis in acute cerebral infarction with that of intravenous thrombolysis.

目的 观察急性脑梗塞患者脑动脉内溶栓与静脉内溶栓的疗效及安全性。

DSA features included: dilatations of brain venule could be seen and the number of brain veins increased; the circulati...

其DSA影像学主要表现为:全脑小静脉扩张、迂曲、数目明显增多;全脑动静脉循环时间延长;丘纹静脉和大脑内静脉系统显影增粗、扩张,并发生深静脉滞流,呈现出"雪花样"表现;静脉窦内对比剂滞留、显影延迟或残缺不全。结论:DSA全脑血管造影是诊断脑静脉系统血栓的可靠方法。

The steps are as the following:1、Preparing the cerebrospinal fluid one hour before the experiment,take some of them for cryopreservation;2、Without paralyse,cuting down the rat head quickly and dislodge the hippocamp part which is used in the experment in freezing liquid,and trim the hippocamp distrct.3、Fixing the hippocamp tissue on the vibratome,to cut down a brain slice with 300μm,use the haustorial tube to move the slice to the preincubate dish,cultivanting it for one hour.Then move it to the record incubation chamfer.4、Preparing the glass micloelectrode and fill it with NaCl,the corcentation is 3mol/L.5、adjusting the recorder,after cultivate the brain slice in the incubation chamfer for 2 hours,the expermentize can be gone on.6、In order to ensure the accurate of the experimental result,use only one medicine concentration for one brain slice in every experiment.

本实验研究方法是:1、实验前1小时配制好所需脑脊液并充以95% O2和5% CO2的混合气,取小部分冷冻保存;2、在乙醚麻醉下,快速断头并在冷冻液里取出包含海马的大脑部位,修整出所需海马区;3、将海马组织固定于振动切片机上切出300μm厚的海马脑片,用广口吸管转移至预孵育皿培养一小时,后再转移到记录用孵育槽内;4、拉制好玻璃微电极,并充以3mol/L的NaCl;5、调试好记录仪器,将脑片在孵育槽内培养2小时后进行实验;6、为了保证实验结果的准确性,每一块脑薄片只进行一个浓度的药品实验。

Results: Cerebral low density lesion was absorbed in 3 months;HIE might cause ext ernal hydrocephalus at 3rd-6th month,and EH disappeared one year later;HIE might cause periventricular leukomalacia after the 3rd month.The incidenc e of PVL was 11.6%,64.3%and 80%,respectively with mild,moderate and severe degree HIE,and that of severe degree PVL was 20%,33.3%and 75%. Severe degree HI E might cause cerebral malacia and atrophy (80%) in 2 months.

结果:HIE所致脑低密度灶在生后3个月内吸收消失;3~6个月时可引起外部性脑积水,1岁以后,EH的表现消失;3个月及以后可引起脑室周围白质软化症,其中轻、中、重度HIE的PVL发生率为11.6 %、64.3%和80%;重度PVL的发生率为20%、33.3 %和75%;重度HIE在2个月内可引起脑软化和脑萎缩(80%)。

Neurogenesis and development of the central nervous system in the embryo stage of swimming crabs, Portunus trituberculatus, were studied by the histological method.

应用组织学方法研究三疣梭子蟹胚胎期中枢神经系统的发生和发育,光学显微镜下镜检切片,在第二期卵内无节幼体阶段开始观察到脑;第二期卵内状幼体阶段,前脑由视神经层、侧原脑和中央原脑组成,与位于食道两侧的中脑和后脑形成完整的脑。

Results Serum EDLS increased within 24 h after brain trauma of different degree in all patients with brain injuries of various intensities.The group of slight injury was the most typal,EDLS demonstrated no change or decrease in a few patients with the injury intensity growing;In most cases EDLS decreased after brain operation or accompaning the wounded recovery; Contents of EDLS at 24 h among different pathological types of brain injuries showed no difference, but in the successful recovery patients with severe or ultra-severe brain injuries, EDLS contents at 72 h posttrauma were lower than in the patients of death or disability. The above change characteristics of EDLS related to injury locations and the degree of brain injury.

结果 不同程度脑外伤后24小时内血清EDLS均升高,以轻伤组最为典型;随着损伤程度的加剧,少数病例EDLS不变甚至下降;术后或随伤情的恢复,EDLS多同步下降;不同病理类型的脑损伤24小时内EDLS无明显差异,在成功康复的重型、特重型脑损伤病人,伤后72小时EDLS含量低于死亡或伤残组;EDLS 的上述变化特点与损伤部位和程度不同有关。

MethodsFocal cerebral ischemia was produced by permanent occlusion of the proximal of the right middle cerebral artery. The neurologic status of each rat was carefully evaluated at 24 h after surgery. The cerebral infarction numbers of neurons and nissls stains ,the water content were measured. Acute incomplete cerebral ischema was induced by ligaturing bilateral carotid arteries. Anoxia was produced by close normobaric hypoxia.

方法电凝大鼠一侧大脑中动脉造成局灶性脑缺血,观察脑血舒通对大鼠行为、大脑皮质内脑梗塞区神经细胞数量、尼氏小体含量、脑组织含水量的影响;采用结扎小鼠双侧颈总动脉形成急性脑缺血模型,并进行了小鼠常压耐缺氧实验,观察小鼠存活时间。

Low-dose naltrexone, at higher doses may block the endorphin and enkephalin receptors, about 3 or 4 hours to eliminate from the body - but the elevated concentrations of endorphin and enkephalin One day can be maintained.

低剂量纳曲酮,在较高剂量时可阻断内啡肽和脑啡肽对受体的作用,大约3或4小时内从体内消除--但升高的内啡肽和脑啡肽浓度可维持一天。

In our research,Wistar rats and SD rats which were parathyroidectomized were used as donors and recepients respectively.The parathyroid gland of the Wistar rat were allografted into the cerebroventricle and other different sites of the brains in SD rat s tereotaxically. Using methods of testing serum Ca~(2+) concentration,histological examination,histochemical and immunocytochemical methods and electron microscopic observation,we investigated the survival of the grafting tissue,its revascularization, infiltrating of monocytes, changes of microglia and astrocytes, the relationship of the CNS with the immune system, and the mechanism of rejection were investigated.The results as following: I .Effects on PTG after allografting into cerebroventricle and cerebral parenchyma of the brain: Testing serum Ca~(2+) conc.

本研究以Wistar大鼠作为供体,切除甲状旁腺的SD大鼠作为受体,在立体定位下将同种异体的PTG移植到大脑的不同部位,设计了侧脑室-内分泌系统移植的代替途径,比较了侧脑室内移植和脑实质内移植的异同,通过测定血清Ca~(2+)的浓度、组织学检查、组织化学和免疫细胞化学以及电镜观察对移植后PTG组织的存活、血管的再生、单核细胞的浸润、CNS内胶质细胞的变化、对免疫系统的影响及免疫排斥的机制进行了研究,结果如下:一、同种异体PTG侧脑室内移植与脑实质内移植的比较:血清Ca~(2+)的检查发现,PTG侧脑室内移植后第7天,血清Ca~(2+)的浓度恢复到8mg%以上,一直持续到移植后第8-12周;移植后第12周仍有60%移植PTG的动物血清Ca~(2+)维持在正常水平。

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