脑内的

Its biochemical basis is increase of content of inhibitory amino acid in brain.

其生化基础是脑内抑制性氨基酸的含量升高。

The suboccipital retrosigmoid approach was used on 10 adult head specimens which were fixed and perfused with color silicon, the neurovascular structures and their relationship in cere- bellopontine angles were observed under the operative microscope and endoscope.

选择经10％福尔马林充分固定，血管内灌注混有红、蓝染料的乳胶，不分性别的成人尸头10具，模拟目前临床上最长使用的枕下乙状窦后入路，在手术显微镜和神经内窥镜下，观察小脑桥脑角内的神经血管结构，确认这些神经血管的走行及其之间的解剖关系。

RESULTS:The irregular and damaged hemosiderin rim may be a important clue to consideration of AICM in the differentiation of hemotoma; The intraventricular metastases are commonly well-circumscribed and tended to seed early.

在转移瘤与脑内血肿的鉴别诊断应注意血肿周围含铁血黄素沉积圈的完整性和规则性；脑室内的转移瘤常有清楚的界面，但发生早期种植转移

The former, intracranially complements patients some factors, most frequently with TH gene to compensate scanty of intrastriatal DA and improve the symptoms of the patients, while have little resistance to the progressive degeneration of dopaminergic neurons; The latter provide variety of neurotrophic factors, most specific being the glial cell-line derived neurotrophic factor , to protect the residual DA neurons in the nigrostriatal system from further pathogenic injuries, while have little benefit to those DA neurons with irreversible damage, and them cannot offset the already-existing symptoms.

前者是给宿主脑内补充某些因子，主要是DA合成过程中的限速酶TH基因，以补充纹状体内DA含量的不足，减轻患者的症状，但对DA能神经元的进行性退变没有治疗效果；后者则是提供各种神经营养因子其中最具特异性的为GDNF，以保护黑质一纹状体系统内剩余的DA能经元免受病因的继续损害但对已发生不可逆性损害的DA能神经元并无拯救作用，无法消除已出现的症状。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果，本论文首次提出以下论点：（1）ACTH在脊髓水平对抗阿片镇痛具有受体选择性，即ACTH可对抗μ受体和δ受体介导的镇痛，不对抗κ受体所介导的镇痛；（2）由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力，与μ受体的非肽类配体的结合位点以及δ受体无亲和力，推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的；（3）ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用；（4）ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应；（5）通过Fos蛋白的诱导揭示：ACTH可以作用于脑内多个核团，其中包括许多与痛觉调制有关的核团，推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

Methods At first, retrovirus vectors encoding IFN-γ or IL-4 gene were constructed. They were transfected into PA317 packaging cells by lipofectamine, PA317IFN-γ and PA317IL-4 cells were obtained. C6 glioma cells were infected with replication deficiency retrovius containing IFN-γ or IL-4 gene, cell morphology、cell growth curve and cloning efficiency assay were examined. The intracranial C6 glioma animal model was established in immunocompetent Wistar rats. PA317IFN-γ and PA317IL-4 cells were stereotactically implanted into the tumor areas alone or together. The survival of tumor bearing rats were examined, tumor volumes were measured and immunohistochemical analyses of CD4〓 and CD8〓 T lymphocyte infiltration were performed.

构建和鉴定携带IL-4或IFN-γ基因的逆转录病毒载体，将其导入逆转录病毒包装细胞PA317，通过G418抗性筛选，得到携带目的基因的包装细胞并鉴定；应用携带IL-4或IFN-γ基因的复制缺陷型逆转录病毒感染C6胶质瘤细胞，观察对C6胶质瘤细胞形态、细胞生长曲线和克隆形成率的影响；建立C6胶质瘤大鼠脑内移植动物模型，将携带IL-4和IFN-γ基因的逆转录病毒包装细胞分别或联合注射到脑内荷瘤大鼠的肿瘤组织中，观察其治疗作用，并初步探讨其机制。

Results GFAP-immunoreactive cells in the control mice were observed mainly within hippocampal formation, piriform, entorhinal cortex, septum, striatum, amygdaloid nucleus, subcortical white matter, as well as in the main fiber tracts.

结果：PBS注射的对照组动物脑内GFAP阳性的星形胶质细胞主要分布于海马、梨状皮质、内嗅皮质、隔区、纹状体、杏仁核及主要的纤维束。

There is a close relationship between monoamines and learning and memory. NE and dopamine are believed to have a role in facilitation of memory. For this, an observation of clausenamide on monoamines and their metabolites as well as monoamine oxidase B activity was carried out.

目前认为脑内单胺类递质的变化与学习记忆密切相关，其中DA，NE的增加有助于学习记忆的形成，为了探讨黄皮酰胺的促智作用机制，我们首先研究了黄皮酰胺对小鼠脑内单胺类递质及其代谢产物和单胺氧化酶的影响。

BACKGROUND: Bone marrow stromal cell transplantation in the ventricle and corpus striatum improves the symptoms of Parkinson's disease rat models and increases dopamine levels in the brain.

背景：研究证实脑室内、纹状体内移植骨髓基质细胞，能够改善帕金森病模型大鼠的症状，并增加脑内多巴胺的水平，目前仅有骨髓基质细胞治疗帕金森叠加综合征的个例报道。

BACKGROUND: Bone marrow stromal cell transplantation in the ventricle and corpus striatum improves the symptoms of Parkinson's disease rat models and increases dopamine levels in the brain. There are case reports of bone marrow stromal cells for treating Parkinson's plus syndrome.

背景：研究证实脑室内、纹状体内移植骨髓基质细胞，能够改善帕金森病模型大鼠的症状，并增加脑内多巴胺的水平，目前仅有骨髓基质细胞治疗帕金森叠加综合征的个例报道。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。