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objective to raise the level of regarding congnition,prevention,diagnosis and therapy on multiple organ dysfunction syndrome.methods report the process and correlative therapy on one case who occured with mods involving 6 organs after hemorrhagic shock lead to heartbeat and respiration stopping suddenly and resuscitated resulting in left nephrostome titanium nip falled off accidentally from left kidney lymphatic fastening.at the same time,the author reviewed correlative literature and introduce the investigative progress about mods.results one case who happened with mods following hemorrhagic shock,heartbeat and respiration stopped suddenly was diagnozed and resuscitaed.6 organ dysfuncted including brain,heart,lung,liver,kidney and the digestive system.after being given therapy integrated chinese and western medicines,allopathy and nutritional treatment,all circadian parameters of the case came back in gear and discharged at last.conclusion the mechanism about mods is very complicated.because of serious infection,hurt and oxygen-lack,excessive inflammatery reaction activates multifarious cell factors and inflammatery mediums,which improve the happen-rate of mods.wiping off pathogeny,providing life-sustain treatment and recognising sirs and mods in time and adopting corresponding therapy,such as treatment integrated chinese and western medicines,can improve the hit-rate of cure on mods.

作者:王静恩,蔡金芳,王志华,谢晓洪多器官功能障碍综合征;中西医结合;治疗;休克,出血性目的提高对多器官功能障碍综合征(multiple organ dysfunction syndrome,mods)的认识、预防、诊断、治疗水平。方法报告成功抢救1例经腹腔镜左肾淋巴管结扎手术后左肾静脉钛夹意外脱落失血性休克,导致心跳呼吸骤停复苏后再手术并发mods累及6个脏器功能衰竭过程及有关治疗,并复习相关文献,介绍目前关于mods的研究进展。结果确诊1例因失血性休克心跳呼吸骤停复苏后并发mods,累及脑、心、肺、肝、肾、血液、胃肠等6个脏器。经积极采取中西医结合对症、支持救治,各生理指标全部恢复正常,康复出院。结论 mods的发生机制非常复杂,在严重感染、创伤、缺氧等打击下,失控的过度炎症反应激活多种细胞因子和炎症介质的释放,使mods发生率升高。尽早去除病因,尽早给予各种生命支持治疗,尽早对可能发生全身炎症反应综合征、mods识别并给予干预治疗,包括中西医结合治疗能改善mods的救治成功率。

The distribution of the two genotyped Ascaris in the organs or locations was different which was characterized by obvious difference in the number of larvae recovered.

两种基因型幼虫在小鼠脏器的分布有所差异,G1型幼虫在各脏器的检出数明显多于G3型幼虫。

Results: The radioactivity in organs in ANP group was higher than other groups'in experiment 1; In experiment 2, the results of cultures of chyle fluid, pancreas, lymph node from the experimental group were positive, whereas the results of cultures of all organs in ANP group were positive.

结果:实验一结果表明ANP组中各脏器的放射活性明显高于其它组;实验二组中实验组乳糜液、胰腺、淋巴结细菌培养阳性,而ANP组中各脏器细菌培养均阳性。

The changes of liver suggested the reversible cell injury and detoxication.

在各脏器中,利凡诺在肝脏中的蓄积量及时间明显地大于其它脏器

Results: Regression equation of standard curve was A=151.33+87136x (r=0.9999), and linear range was between 0.0418 and 0.2508μg; the average recovery was 99.4%. The results of the tissue distribution demonstrated that harmine levels in stomach, lungs, liver, brain and heart in the emulsion group were higher than those in the suspension group, with the highest conc entration in stomach.

结果:方法学考察表明,标准曲线回归方程为A=151.33+87136x(r=0.9999),线性范围0.0418~0.2508μg,平均回收率99.4%;小鼠体内试验显示,harmine乳剂组在胃、肺、肝、心等脏器中的药物分布均高于混悬液组,且胃内harmine水平大大高于其他脏器,并在较高浓度维持较长时间。

In this paper the effects of mercury chloride on the coefficient of visceral organ of mouse and the meiotic maturation and the fertilization ability of mouse oocyte were studied by in vitro culture and in vitro fertilization of mouse oocytes,etc.

为探讨汞化合物对脏器及生殖的毒性,采用卵母细胞体外培养、体外受精的方法研究了汞对小鼠脏器系数、卵母细胞成熟和受精能力的影响。

Methods The clinical data of patients with MODS were collected and analyzed prospectively. Seven indicators were screened out to assess the functions of seven organs. Each indicator was scored from 0 to 4 points, with the 0 point representing the normal organ function, and 1 point to 4 points representing the dysfuntion to failure of the organ.

收集MODS临床资料,通过统计分析筛选出反映脏器功能的指标并赋予各指标反映病情严重程度的等级分值,分值范围为0~4分, 0分表示脏器功能正常, 1~4分表示脏器功能障碍至衰竭,据此建立MODS病情严重度评分系统。

The script of diagnostic criteria for MODS with the illness severity score system was established. The script mainly was involved in the evaluation of seven organs or systems, including respiratory system, cardiovascular system, kidney, hemologic system, liver and alimentary system. Only one parameter was used in each organ, they were FiO2/PaO2, systolic blood pressure, serum creatinine, platelet count, conscious state and the defecation status. 0- 4 scores were endued with each indexaccording to the severity of the illnesses respectively. Every descriptor was 5 points, showing 0 point with normal organ function, and 1- 4 scores with organ dysfunction and aggravation.

建立了MODS诊断标准、病情严重度评分系统草案:主要纳入呼吸、心血管、肾脏、凝血、脑、肝脏、胃肠道7个脏器系统,每个脏器系统仅用1个指标表示其功能障碍与否,分别是氧合指数、收缩压、血清肌酐浓度、血小板计数、意识状态、血清总胆红素浓度、排便状况;每个指标结合病情严重程度分别赋予0~4分,0分为功能正常,4分为器官功能衰竭,1~4分为器官功能发生障碍且程度逐渐加重。

Infection positions are inclined to lead to abscess, then invade into organs and blood stream and results in organic abscess for marion, pyemia is another clinical character of Chromobacterium violaceum infection.

可引起感染部位脓肿,并可侵入体内各脏器及血液引发脏器的脓肿,脓毒血症是该菌感染的临床特症,重者可引起各脏器功能衰退,中毒性休克甚至死亡。

Results: In acute experiment, there was no significant difference of body weight or organ indexes between the normal control and arsenic poisoning groups ; while the CH50 level, lymphocyte accruing rate, phagocytosis rate and macrophagocyte index in arsenic poisoning group were significantly lower (P.05 or P.01) than those in normal group. There was no significant difference of body weight or organ index between arsenic poisoning group and EXD (10 g) treated arsenic poisoning group, while CH50, lymphocyte accruing rate, phagocytosis rate, and mavrophocyte index were significantly higher in EXD (10 g) treated arsenic poisoning group than those in arsenic poisoning group (P.05 or P.01). In EXD (5 g) treated arsenic poisoning group, results of all the tested indexes were the same as those of arsenic poisoning group.

结果:与正常对照组相比,砷中毒组小鼠体重、脏器指数无明显改变;CH50、淋巴细胞增殖、巨噬细胞吞噬率及吞噬指数明显降低,差异有显著性(P.05或P.01;与砷中毒组相比,竹荪治疗低剂量组小鼠体重、脏器指数、CH50、淋巴细胞增殖、巨噬细胞吞噬率及吞噬指数无明显改变化;竹荪治疗高剂量组除小鼠体重、脏器指数无明显改变外,CH50、淋巴细胞增殖、巨噬细胞吞噬率及吞噬指数明显升高,差异有显著性(P.05或P.01)。

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