脊髓运动神经元

Results: On day 12～ 18, rats were paralyzed on its 2 hind limbs, the coronal sections of lumbosacral enlargement of spinal cord with HE stainning showed that there were dilated capillaries, perivascular oversleeve-like inflammatory infilltration and anterior-horn motor-neuron hydropic degeneration.

结果：在接种后12～18天，大鼠出现双后肢瘫，脊髓横切片HE染色可见血管周围袖套样炎性细胞浸润和前角运动神经元肿胀变性。

Under the presupposition of no evident of muscle atrophy through maximal electrical twitch, quantitative electromyographical test of patellar reflex could discover the quadriceps AMI in patients with knee OA,which was known to be the inhibition of anterior horn motoneuron.

小结：在电刺激表明肌萎缩不明显的前提下，定量腱反射的肌电图检查显示膝OA的股四头肌有明显的AMI，此关节源性肌肉抑制为脊髓前角运动神经元的抑制。

By 14 days after operation, the expression of GAP -43 mRNA was evidently up -regulated compared with control group.

用免疫组化方法检测术后1、3、7、14d脊髓前角GAP-43免疫阳性运动神经元的表达。

RESULTS: The positive staining cells mostly included ependymal cells of myelocoele, glial cells, motor neurons, and epithelial cells of spinal pia mater. The staining was mainly located on the cell membrane. Most importantly, it displayed certain directivity in the glial cells, mainly at the membrane side contacting with capillary endothelial cells.

结果： 免疫组织化学染色结果显示阳性着色细胞包括有胶质细胞、中央管室管膜上皮细胞、脊髓前角运动神经元、软脊膜上皮细胞，着色部位主要在细胞膜，其中在胶质细胞表现出一定的方向性，主要分布在与毛细血管内皮细胞接触的一侧。

Of the other 16 patients with ALS whose upper motor neurone signs were not so manifest (cases 6-21), high signal was seen in the corticospinal tract on T2-weighted images was seen in 11 (cases 6-12, 16-18 and 21); five (cases 6, 7, 11, 12 and 16) of these also showed high signal on the PD-weighted images.

另外16例ALS患者（病例6~21）上运动神经元症状体征不明显，在T2像上有11例可见皮质脊髓束高信号病灶（病例6~12、16~18、21）；在PdWI像上有5例也可见高信号病灶（病例6、7、11、12、16）。

Further study is required to establish whether the high signal intensity in the intracranial corticospinal tract on T1 weighted images correlates with the severity of the upper motor neurone

但，仍需要进一步研究以明确T1像上颅内皮质脊髓束的高信号改变是否与上运动神经元病灶的严重性相关。

High signal on T1 weighted images in the intracranial corticospinal tract may be specific for ALS and may correlate with the severity of the upper motor neurone lesions.

T1像上颅内皮质脊髓束的高信号改变对ALS而言可能具有特异性，并可能与上运动神经元症状体征的严重程度存在关联性。

In addition, five patients with ALS with severe upper motor neurone signs such as spastic paraparesis showed high signal in the intracranial corticospinal tract on T1-weighted images as well as on T2- and PD-weighted images.

另外，5例表现出严重的上运动神经元症状体征的ALS患者，在T1、T2、PdWI这3像上，都于颅内皮质脊髓束走行区表现出高信号病灶。

The NSE immunohistochemical reaction could be shown in the cell bodies and axons of motorneurons after 4 h of reperfusion, and the distribution of NSE in the cell bodies was divergent, rare and disintegrative, the axons were swollen and vanish.

再灌流4小时，脊髓前角运动神经元胞体和轴突内NSE反应阳性，胞体内NSE散乱、稀疏和溶解，轴突肿胀、扩大、消失。

Objective:To investigate the protective effect of glial cell line-derived neurotrophic factor on spinal front corner motor neurons.

目的：探讨胶质细胞源性神经营养因子对脊髓损伤后运动神经元的保护作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。