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脊髓运动神经元

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Using CB-HRP antidromic tracing technique, the distributions of MNs innervating the muscles of three-Yang and three-Yin meridian of hand in spinal anterior horn were investigated and the dendritic progections between the MNs of homo-meridian were observed.

利用CB-HRP逆行示踪法,研究支配大鼠手三阳经和手三阴经上肢部所属肌肉运动神经元在脊髓前角的分布,观察同经运动神经元间的树突投射联系。

Injury to the corticospinal tract, which has facilatory influence on motor neurons in the spinal cord, causes the "negative" manifestations including muscle weakness, fatigability, and decreased dexterity (Rossi, 1994). These features are the major determinant of motor disability associated with upper motor neuron lesions.

痉挛在极易影响运动神经元的脊髓灰质损伤中带来的阴性效应包括肌肉无力、易疲劳、灵巧性下降,这些特征成为与上运动神经元损伤并发的运动残疾的主要决定因素。

The areas, grey levels of NSE in the cell bodies and the numbers of axons in the anterior funiculus were measured and the statistical analysis showed the significance difference.

图像分析了脊髓前角运动神经元胞体内 NSE的面积、灰度和脊髓前索内轴突的数量,其结果具有显著性差异。

Expression of islet-1 in spinal cord of adult rat.In grey of the spinal cord of adult rat, the results of both of ISL1 immunohistochemistry and islet-1 mRNA in situ hybridi-zation showed that islet-1 gene expressed predominantly in the nuclei of motoneurons in ventral region and some cell around central canal and dorsal region. In white of spinal cord, the expression of islet-1 located in astroglia in anterior and dorsal funiculus.

在正常成年大鼠脊髓灰质中,ISL-l免疫组化和islet-lmRNA原位分子杂交结果都显示islet-1在腹侧角运动神经元中有相当强度的表达;在中央管周围和背侧角胶状质也有islet-1阳性表达细胞存在;在脊髓白质中,islet-l在腹侧索和背侧索中的星形胶质细胞有表达,外侧索相对较少。

No atrophy was found in the surviving motoneurons, and the expression of NOS was inhibited. Conclusion SDNF can prevent the motoneurons from death following spinal root avulsion. NO may play a role in the injury-induced motoneuron death.

SDNF对脊髓前角运动神经元死亡有明显的保护作用,NO在臂丛神经根性撕脱所致运动神经元死亡中起一定作用。

From 136 to 138, the expres- sion retrieved ventrally and expressed at the ventral half of the central tube (137) and the ventral horn especially in motor neurons (E7 and E8). Thus, the dorsal terminating axons relating to nociception and thermore?

到民至 Es麻Sema 3A的mRN的表达向腹侧撤退,主要在脊髓中央管周围的腹侧和前角运动神经元,这样使背侧投射性的痛温觉神经元轴突仅进入脊髓后角第 I、11层而不进一步向腹侧投射。

Results: The sensory neurons in DRG constitutively expressed Robo2 mRNA and protein, but no expression was in spinal cord.

结果:正常DRG感觉神经元表达Robo2 mRNA和蛋白质,脊髓前角运动神经元不表达。

The long latency reflexes might bemonosynaptic responses mediated by dorsal root excitement, while the short latencyreflexes might be sarcous electric activity mediated by direct excitement of motor neuron ormotor fiber.

长潜伏期成分可能是兴奋脊髓背根传入神经后引起的单突触反射;短潜伏期成分可能是直接兴奋脊髓内的运动神经元或运动纤维后向下传导引起的肌肉兴奋电反应。

The MNs innervating homo-meridian have relative independent locations in spinal cord.

支配同一经络的运动神经元在脊髓中枢有相对独立的分布区域,沿脊髓长轴形成运动神经元柱。

It was observed by Nissl and enzyme histochemistry staining that exogenous GDNF decreased lesion-induced motor neuron death in lateral nucleus of spinal anterior horn and the changes in activity of cholinesterase and acid phosphatase in spinal cord and sensory ganglions.

采用硅管套接大鼠切断的坐骨神经模型,局部给予胶质细胞源性神经营养因子,应用尼氏染色、酶组织化学染色方法,观察到外源性GDNF能减少脊髓修复侧前角运动神经元死亡的数目,降低脊髓前角运动神经元及脊神经节感觉神经元中胆碱酯酶及酸性磷酸酶变化的幅度。

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