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Chinese pharmaceutical compositions for treating epidemic cerebrospinal meningitis and processes for preparation thereof.

本发明涉及中药领域,流行性脑脊髓膜炎是由膜炎双球菌引起的脑脊髓膜炎的急性传染病。

Result:MRI could find the level of conus tip and the pathological changes of filum,terminus,spinal lipoma,spinal cord and spinal column.

结果:MRI可详细了解脊髓圆锥的位置、终丝、椎管内外脂肪瘤、脊髓脊膜以及脊柱等的各种病理变化。

The positive expression of Slit2 located in the cytoplast on oligodendrocyte and astrocyte.The positive cells were found at 3d after spinal cord injury, reached peak on 7d after injury, declining after 14d. The change of Slit2 was correlative with the rehabilitation and regeneration of the axon on the forepart period.

免疫组织化学检测:Slit2蛋白定位于星型胶质细胞和少突胶质细胞的胞浆,呈棕黄色染色,于脊髓损伤后第3 d出现,阳性细胞逐渐增多,于脊髓损伤后第7 d,Slit2阳性表达的细胞数达到高峰并趋于稳定,伤后第14 d开始逐渐下降,呈一过性增高。

The spinal cord lesions in our patient, demonstrated by MRI, may not have been the cause of his diplegia.

我们认为,本例患者脊髓MRI所显示的脊髓病灶可能并非导致患者双侧瘫痪的原因。

Objective:To investigate the expression of axon guidance cue slit-2 mRNA, and the ethology and morphology changes in different phases of spinal cord injury development.

目的:研究脊髓损伤后轴突导向因子slit-2的表达变化,同时观察大鼠行为学及脊髓形态学的变化特点?

The areas, grey levels of NSE in the cell bodies and the numbers of axons in the anterior funiculus were measured and the statistical analysis showed the significance difference.

图像分析了脊髓前角运动神经元胞体内 NSE的面积、灰度和脊髓前索内轴突的数量,其结果具有显著性差异。

Expression of islet-1 in spinal cord of adult rat.In grey of the spinal cord of adult rat, the results of both of ISL1 immunohistochemistry and islet-1 mRNA in situ hybridi-zation showed that islet-1 gene expressed predominantly in the nuclei of motoneurons in ventral region and some cell around central canal and dorsal region. In white of spinal cord, the expression of islet-1 located in astroglia in anterior and dorsal funiculus.

在正常成年大鼠脊髓灰质中,ISL-l免疫组化和islet-lmRNA原位分子杂交结果都显示islet-1在腹侧角运动神经元中有相当强度的表达;在中央管周围和背侧角胶状质也有islet-1阳性表达细胞存在;在脊髓白质中,islet-l在腹侧索和背侧索中的星形胶质细胞有表达,外侧索相对较少。

Objective To study the effects of ciliary neurotrophic factor on the expression of glia fibrillary acidic protein mRNA and on the functional recovery after spinal cord injur in rats.

目的 研究大鼠脊髓损伤后睫状神经营养因子是否能够影响胶质纤维酸性蛋白的表达和脊髓损伤后大鼠功能的恢复情况。

Materials and Methods: Forty Sprague-Dawley rats were randomly divided into normal group, control operative group and operative group which includes 6 subgroups (1,3,7,14,21,28 days). The spinal cord hemisection injury model was made by cutting the posterior right side spinal cord. Function changes in the right posterior limb were evaluated by BBB method. The general morphology changes were observed by HE stain.

材料与方法:40只成年SD大鼠随机分为正常组,假手术组和手术组,手术组又分成1,3,7,14,21,28天组,选取制作脊髓右侧半横断损伤模型,BBB法进行右下肢功能评分,HE染色观察损伤脊髓不同时段的大体形态学变化,原位杂交法观察slit-2 mRNA的表达变化,计算阳性细胞灰度值,进行统计学分析。

Objective: To study the expression level of MCP-1 mRNA after spinal cord injury and its role in the secondary immunoreaction at the early stage after SCI.

目的:探讨炎症细胞趋化因子单核细胞趋化蛋白1(MCP-1)在脊髓损伤早期的表达变化及其在脊髓继发性损伤炎症免疫反应中的作用机制。

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