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In normal group and sham lesion group, BDA positive neurons were distributed symmetrically in the pyramid cells of sensorimotor cortex, and BDA positive fibers of pyramid cells passed through the cerebral cortex, internal capsule, cerebral peduncle of midbrain, basilar portion of pons to the pyramid of medulla oblongata. At the lower part of the medulla oblongata, most of the BDA positive fibers passed through the pyramidal decussation to the contralateral side, continously descended at the ventral part of posterior funiculus just dorsal to the posterior gray commissure and ended at sacral spinal segments.

正常组和假损伤组大鼠BDA示踪显示BDA标记阳性细胞定位于双侧感觉运动皮层的锥体细胞,锥体细胞发出的BDA阳性纤维束对称分布于双侧皮层、内囊、大脑脚、脑桥基底部、延髓锥体中的皮质脊髓束内,继而经锥体交叉到脊髓后索,在双侧后索最深层、灰质后连合背侧下行至脊髓骶段。

These DSs were first observed at 9 weeks in the distal part of ascending fibers that consist of gracile fasciculus and cerebellospinal-gracile nucleus and white matter of cerebellum. They extend along medulla oblongate to medulla cervix、medulla thorax、medulla lumbalis in accordance with dying-back type degeneration. The corticospinal tract were affected at 18 weeks,and thalamus、the olfactory pathway、the visal pathway、the auditory pathway were affected at 32 weeks.

这种DS从9周龄开始,首先在构成薄束路和脊髓小脑后路的上行纤维的远端区域-薄束核区和小脑白质出现,逐渐按照延髓、颈髓、胸髓、腰髓的顺序,向细胞体方向逆行性地进展。18周龄时波及到锥体路,32周龄时进一步波及到丘脑和嗅觉、视觉、听觉传导路。

The same results were observed in the brain of the unilateral pyramidotomy group above the level of the transection site. Below the level of the transection site, the BDA positive fibers were seen in the right pyramid of medulla oblongata and the left dorsal funiculus of spinal cord, but the BDA positive fibers in the left pyramid of medulla oblongata and the right dorsal funiculus of spinal cord were not seen.

锥体束横断损伤大鼠在损伤部位以上可见双侧对称的BDA阳性纤维束,损伤平面以下在右侧延髓锥体和左侧脊髓后索中见有BDA阳性纤维束,损伤侧锥体和右侧脊髓后索中未见有BDA阳性纤维束。

Objective To investigate the distribution of protein kinase C gamma in medulla oblongata and white matter of the spinal cord in adult rats.

目的 观察蛋白激酶Cγ亚型在成年大鼠延髓和脊髓白质内的分布。

The distribution of PKCγ in medulla oblongata and white matter of the spinal cord in adult rats are correspondent with the position and course of the rat corticospinal tract.

PKCγ免疫阳性反应产物在延髓锥体和脊髓后索内的定位与大鼠皮质脊髓束的位置和走行一致,提示其在运动神经传导通路中可能起着重要作用。

We identified a novel NMO lesion in the spinal cord and medullary tegmentum extending into the area postrema, characterized by AQP4 loss in foci that were inflammatory and oedematous, but neither demyelinated nor necrotic.

我们在对脊髓和延髓背盖延伸入最后区的一个异常NMO病灶研究中证实,该病变仅表现为以AQP4缺失为特征的炎性水肿,既无脱髓鞘也无坏死。

Low signal was also seen in the motor cortex on T2-weighted images in three of the eight normal volunteers and four of the 16 disease controls: one with a bulbospinal muscular atrophy, two with leukoencephalopathy and one with Binswanger's disease.

在8例正常人对照者中有3例、16例其他神经疾病患者中有4例(1例脊髓延髓性肌萎缩症患者、2例表现为下肢痉挛性轻瘫的不明原因的白质脑病患者、1例表现为痴呆和下肢痉挛性轻瘫的皮质下动脉硬化性脑病患者)在T2像上于运动皮质区也可见低信号。

Of the 26 lesions with pontine and bulbar involvement, three had no association with other lesions (Fig 2). Twelve were associated with tegmental and superior cerebellar peduncular extension, and six showed corticospinal tract involvement in continuity with an MDJ lesion. In one patient with additional telencephalic lesions, the right side of the pons was hyperintense on long TR/TE images that did not cross the midline, suggestive of an arterial lesion (Fig 3). In two patients with pontine tegmental lesions, there was an associated middle cerebellar peduncle and deep cerebellar white matter involvement (Fig 4). Two others had associated cervical lesions.

在26处脑桥延髓区病灶中,3处病灶仅限于脑桥延髓区,其它部位无病灶(图2);12处病灶还同时伴有背盖部和小脑上脚/结合臂处病灶;6处病灶为与中脑-间脑接合处病灶相连的皮质脊髓束受累;还有1例患者除端脑见病灶外,右侧脑桥于T2像也见高信号病灶,但未超越正中线,提示可能系动脉病变所致(图3);2例脑桥背盖部病灶的患者同时伴有小脑中脚/小脑脑桥脚和小脑深部白质受累(图4);还有2处脑桥延髓区病灶还同时伴有颈髓病灶。

Increased expression of PENK mRNA was more marked in the ipsilateral dorsal horn of the spinal cord, especially in lamina Ⅲ-Ⅳ and the contralateral medulla, especially in the gigantocellular reticular nucleus, lateral paragigantocellar reticular nucleus and lateral reticular nucleus.

本实验用原位杂交技术对电针刺激后前脑啡肽mRNA在脊髓和延髓的表达进行了观察,发现给予大鼠单侧后肢电针刺激引起脊髓和延髓中PENK mRNA阳性神经元数显著增加,尤其是同侧脊髓背角各层PENK mRNA的表达,和对侧延髓网状结构如网状巨细胞核α部、网状巨细胞外侧旁核及外侧网状核中的PENK mRNA表达增加,这与脊髓上传的信号由同侧脊髓交叉到对侧脑干的走行方式是一致的。

The precise termination areas of the descending projection from the medullary subnucleus reticularis dorsalis to spinal gray matter in the rat were investigated by injection of an anterograde tracer, phaseol us vulgaris leucoagglu tinin into the SRD.

本研究应用PHA-L顺行追踪技术研究了大风延髓网状背测亚核至脊髓灰质下行投射的终止部位。结果表明:SRD发出的下行纤维走行于脊髓的背外侧京中,从高位至低位,脊髓灰质中的PHA-L顺标终末的密度逐渐降低。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

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但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。