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脊髓内神经元

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The PKC α and βI isozyme labelings were mainly associated with the cell surface.

PKC α和βI的高表达主要发生在脊髓背角Ⅰ-Ⅱ层的神经元内,Ⅲ-Ⅳ层中表达PKC α和βI的神经元数量也增加,至少持续28天。

In the end-to-side group, the cutaneous antebrachii medialis nerve was transected, then an 1 mm epineural window was created on the ulnar nerve. Distal end of CAM nerve was sutured to the windowed ulnar nerve by means of end-to-side neurorrhaphy. In the normal control group, CAM and ulnar nerves were exposed. One year post-operatively, evaluations including acetylcholinesterase stain and retrograde Fluoro-Gold neuron tracing were conducted.

端侧缝合组切断前臂内侧皮神经,尺神经后内侧方外膜开窗,将前臂内侧皮神经和开窗的尺神经外膜做端侧缝合,正常对照组仅显露前臂内侧皮神经和尺神经。1年后采用乙酰胆碱酯酶染色和Fluoro-Gold荧光逆行示踪技术,观察和计数前臂内侧皮神经纤维和大鼠脊髓C5~T1前角和背根神经节神经元。

The proximal and distal nerve stumps were sutured l cm apart, in an end-to-side fashion like "π", to the epneurium windows, opened by removing the epineural sheath on the intact tibial nerve trunk with 1 mm long.

方法将大鼠右侧腓总神经在胭窝处剪除约5mm后,将断裂的腓总神经近端和远端分别就近与同侧胫神经上的外膜窗施行端侧吻合,吻合口间距约10mm;动物存活24个月后,将手术侧近端吻合口以上胫神经剪断,再将辣根过氧化物酶注入远段腓总神经干内,72h后取材并经四甲基联苯胺显色显示脊髓L3-6节段神经元和L4、L5脊神经节细胞,同时取腓总神经远段行电镜观察神经纤维再生状态。

The areas, grey levels of NSE in the cell bodies and the numbers of axons in the anterior funiculus were measured and the statistical analysis showed the significance difference.

图像分析了脊髓前角运动神经元胞体内 NSE的面积、灰度和脊髓前索内轴突的数量,其结果具有显著性差异。

Result and Conclusion: TrkA was expressed and distributed ubiquitously in both eytoplasm and dendrites of spinal cord.

结果与结论:TrkA广泛分于脊髓各层神经元及灰质内,并且在神经元的胞体和树突中均有表达。

In rats receiving infusion of 100 μl of 2%formalin into the urethra, a large number of FOS-positive neurons were seen in the lumbosacral cord segments (L6 and S1), and they were primarily distributed in the medial dorsal horn and dorsal commissural nucleus.

在向大鼠尿道内导入100 μl 2%福尔马林后,大量FOS阳性神经元出现在脊髓腰6和骶1节段的后角内侧部和后连合核内。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果,本论文首次提出以下论点:(1)ACTH在脊髓水平对抗阿片镇痛具有受体选择性,即ACTH可对抗μ受体和δ受体介导的镇痛,不对抗κ受体所介导的镇痛;(2)由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力,与μ受体的非肽类配体的结合位点以及δ受体无亲和力,推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的;(3)ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用;(4)ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应;(5)通过Fos蛋白的诱导揭示:ACTH可以作用于脑内多个核团,其中包括许多与痛觉调制有关的核团,推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

Observing localization of the drug and morphologic change in DRG cells and motor neurons in spinal cord anterior hom after 1% adriamycin intraneural injection into the sciatic nerve of rabbits. Moreover, evaluating sensory and motor function 1-8 weeks following injection. Exploring whether the agent, injected into sciatic nerve, has the effect of chemo-ganglionectomy on the corresponding DRG.

研究家兔坐骨神经内注射1%阿霉素后,药物的聚集部位及相应脊髓前角运动神经元和背根节细胞的形态学变化,测定家兔1~8周下肢感觉及运动功能,探讨坐骨神经内注射阿霉素能否对相应背根神经节产生化学切除术作用。

Our observation indicates that capsaicin as a nociceptive chemical irritant can selectively activate primary afferent C-fibers to release SP and Glu from their central terminals in the superficial dorsal horn. It seems that the release of SP and Glu acting on NK-1 and NMDA receptors results secondarily in the activation of dorsal horn neurons, transmitting nociceptive information to supraspinal structures.

以上结果表明辣椒素作为一种伤害性的刺激源,可选择性兴奋C类传入纤维,引起其分布于脊髓背角浅层内的末梢大量释放SP和Glu,通过相应受体兴奋背角伤害性感受神经元,包括上行脊-丘束投射神经元,将痛觉信息传递至脑。

The opioid receptor agonist at the supraspinal site failed to alter the pelvic nerve activity suggest that supraspinal endogenous opioid system does not act directly on the sacral preganglionic neurons, but indirectly through descending fibers on the interneuron at the level of afferent inputs in the sacral spinal cord.

由於注射此药物到侧脑室中,并不会对骨盆神经之活性造成影响,因此推论上脊髓部位的内吗啡系统,并不会直接影响副交感神经节前神经元之活性,其作用可能在中问神经元或膀胱的输入神经。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?