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OBJECTIVE: To explore the effects of different transplantation methods for autologous intercostal nerves on spinal cord injury.

目的:探讨自体肋间神经不同移植术式对治疗脊髓损伤疗效的影响。

RESULTS: Myelopathy of the patient was caused by rupture of a thoracic intervertebral disc.

结果:病人的脊髓病是由于胸椎椎间盘的破裂所致。

The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量,其CSF/S ALB比值作为评价BBB损害的指标;同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析,结果显示如下: 1、EAE大鼠p.i.4-8天无任何临床表现;p.i.10天症状开始明显,症状评分为2.33±0.76(n=6);p.i.12-14天为发病高峰期,症状评分为3.75±0.54(n=12),病情由最初的活动减少,体重减轻逐渐发展为肢体无力、瘫痪,共济失调,甚至濒死状态;p.i.16天大部分动物症状开始缓解,评分为2.08±0.66(n=6);p.i.20天疾病症状完全消失。

Methods With guinea pig spinal cord homogenate in complete Freund's adjuvant or MBP in complete Freund's adjuvant and Bordetella pertussis vaccine was injected intradermally to induce EAE in Wistar rats.

目的 建立实验性自身免疫性脑脊髓炎动物模型,探讨口服自身抗原诱导免疫耐受对大鼠EAE的防治作用。

MRI diagnosis of basilar invagination in 3 cases ,ring pillowfusion deformity in 2 cases, 1case complicated with syringomyelia, and 1 case combined Chiari deformity.

MRI诊断颅底凹陷症3例,环枕融合畸形2例, 1例合并有脊髓空洞,1例合并Chairi畸形。

MRI not only can be multi-dimensional and muiti-parameter display abnormal bone structure, accurate measurement of basilar invagination,but also clearly shows Chiari deformity and syringomyelia and other diseases, MRIis the most accurate and reliable imaging diagnostic methods.

MRI可多方位多参数显示骨结构畸形,准确测量颅底凹陷,还能清楚显示Chairi畸形及脊髓空洞症等病变,MRI是诊断颅颈交界部畸形最准确、可靠的影像学诊断方法。

I am looking forward to reports of beneficial effects of IPS cell transplants in spinal cord injury.

我期待着报告的有利影响了IPS细胞移植治疗脊髓损伤。

We concluded that the clinical efficacy of hyperbaric levobupivacaine was superior to the isobaric form in spinal anesthesia for transurethral resection.

我们认为高压氧levobupivacaine的临床疗效优于isobaric形式是对尿道切除在脊髓麻醉。

All patients received an intrathecal injection of 15 mg of 0.5% isobaric bupivacaine and 0.2 mg preservative free morphine.

所有病人均接受脊髓麻醉并给予15毫克isobaric bupivacaine与0.2毫克不含防腐剂之吗啡。

Lab of Spinal Cord Injury and Repair, Academy of Military Medical Sciences, Beijing 100850〖JZ

军事医学科学院脊髓损伤与修复研究室,北京 100850

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