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In order to understand their mechanisms of blood-lipid regulation, We used the amphotercin B cell model and RT-PCR method to examine the effects of the serum-drugs of SM and FC extracts and their effective monomers, including danshensu, protocatechualdehyde, ursolic acid, quercetin and rutin, on cholesterol biosynthesis in CHO cells and the expressions of CYP7AmRNA and DGATmRNA in BRL cell line.

采用两性霉素B细胞模型和逆转录-聚合酶链反应方法,分别观察丹参和山楂各调脂有效部位以及部分单体(丹参素钠、原儿茶醛、熊果酸、槲皮素和芦丁)对内源性胆固醇合成、CYP7AmRNA和DGATmRNA表达的影响。

Comparative study on the change of lipid peroxidation product and activities of regulatable enzymes by irradiation of N + ion beam and 60Co γ-rays .

顾月华,罗江虹,罗建平,等。N+离子束和60Co γ射线辐照引起脂质过氧化产物及调节酶活性变化的比较研究,核技术,1999,22(8):44-48。

BACKGROUND & AIM: To investigate the changes of semicarbazide- sensitive amine oxidase activity in lipopolysaccharide-induced pulmonary inflammation.

背景与目的:探讨SSAO酶在脂多糖诱导急性肺损伤过程中的活性变化。

Identification of cripto-1 as a novel serologic marker for breast and colon cancer[J].

脂质体介导的cripto反义寡核苷酸抑制结肠癌细胞端粒酶活性[J]。

The effects of drought stress on lipid peroxidation and protective enzyme systems in leaf of Toona sinensisA.

苗进行盆栽实验,研究干旱胁迫对香椿叶片膜脂过氧化和保护酶系统的影响。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1 (IGF-1) and the intervention effect of HMGcoA reductase inhibitor, atovastatin and immune supppressor, rapamycin.

目的:探讨氧化低密度脂蛋白,胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1(IGF-1) and the intervention effect of HMG-coA reductase inhibitor, atovastatin and immune supppressor .rapamycin.

目的:探讨氧化低密度脂蛋白,胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Methods: The model of acute myocardial ischemia in rats was developed by ligaturing the left descending anterior coronary artery. Forty male Wister rats were divided into normal control group, ischemia model group, Xuesetong group and Verapamil group. The effect of Xuesetong on the CPK, LDH, SOD and MDA in serum and myocardium and myocardial infarct range was observed.

采用结扎大鼠冠状动脉左前降支复制出大鼠心肌缺血再灌注损伤模型。40只Wister大鼠分为正常对照组、模型组、血塞通组及维拉帕米组,观察血塞通对大鼠血清磷酸肌酸激酶、乳酸脱氢酶、血清及心肌组织超氧化物歧化酶和脂质过氧化物丙二醛及对心肌梗死范围的影响。

Methods: CHD celerity arrhythmia rabbit models established by high fat and mainlining adrenalin were divided randomly into model group, recuperating-heart granule treat group, recuperating-heart granule prevention group, Amiodarone treat group. Other 7 natural rabbits were comparison group. Then observe the appearing and resuming time and the effects of Na(superscript +)-K(superscript +)ATP ase activity by the way of spectrophotometric method.

用高脂饮食喂养并结合静脉注射肾上腺素复制冠心病快速性心律失常模型,并随机分为模型对照组、养心颗粒治疗组、养心颗粒防治组、胺碘酮治疗组,并另取7只作为空白对照组,观察并比较各组心律失常的出现时间和持续时间,并采用分光光度法测定各组家兔心肌Na-K-ATP酶活性。

Study objective To search the changing of serum Lipid Peroxides content and Glutathione Peroxidase activity in some central nervous system diseases.

研究目的探讨某些中枢神经系统疾病血清过氧化脂质和谷胱甘肽过氧化物酶水平的变化。

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