脂酶

In another experiment, after feeding APP for 5 weeks, low dosage group (15%) significantly decreased UI, liver lipid peroxidation and increased plasma calcium level compared with the negative control group. In high dosage of APP (30%), gastric mucosa and liver lipid peroxidation significantly decreased and amylase, lactase, sucrase, maltase activities significantly elevated compared to the negative control group.

另外，餵食薏仁加工产品五周后，发现低剂量组(15%)与负控制组相比能显著降低水浸润拘束紧迫法处理4小时所造成的溃疡指数，与负控制组相比显著降低肝脏脂质过氧化物含量并增加血清钙浓度，高剂量(30%)下显著比负控制组降低胃黏膜及肝脏脂质过氧化物含量，并且有提高淀粉酶、乳糖酶、蔗糖酶、麦芽糖酶活性。

Effects of Psoralea corylifolia L.extract on the defensive enzymes on cucumber were studied and the results showed that activities of peroxidase,polyphenol oxidase, phenylalanine ammonialyaseof cucumber leaves were increased to highest level after 7 to 9 days at 40 mg/L and 400 mg/L.

补骨脂粗提物处理两叶一心生长期的黄瓜幼苗，补骨脂提取物在40mg/L和400mg/L浓度下，黄瓜体内过氧化物酶、多酚氧化酶、苯丙氨酸解氨酶等一些防御酶活性均在处理后7d～9d达最高。

Metabolic cherry-red spot occurs in other lysosomal enzyme deficiences such as generalized gangliosidosis (GM 1), Sandhoff's, Gaucher's, mucolipidosis Types 1 and 2, Niemann-Pick Type A, and multiple sulfatase deficiency. Vision is usually subnormal because the ganglion cells are not working properly.

代谢性眼部樱桃红斑发生在许多溶酶体酶缺乏的疾病中出现，如GM1神经节苷脂贮积病，sandhoff病，高雪氏病，粘脂质贮积病1，2型，尼曼匹克病A型，及多种硫酸酯酶缺乏病等，由于神经节细胞异常，视力一般轻度受损。

Aim To understand the features of lipoprotein lipase and its role in the distinctive lipid metabolism in tree shrew, which is considered to be an animal protected from atherosclerosis.

目的 了解不易感动脉粥样硬化动物树鼩的脂蛋白脂肪酶的结构和活性特点，并与其它种属比较，探讨脂蛋白脂肪酶在树鼩独特脂代谢中的作用。

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

(1)PAL is better entrapped by PAG with a T∶C ratio of 8∶30.(2)PAL immobilized by glutaric dialdehyde on Bio-Gel P-300 is better than by CDC.(3)The best one is the dehydration and redehydration method.(4)Immobilized and permeated PAL active yeast cells are resistant to trypsin digestion and retain its PAL activity.

(1)固定化酶活性采用T∶C比为8∶30明显高于8∶19；(2)以戊二醛将PAL固定于Bio-GelP300优于用DCD固定化的酶；(3)质脂体包被中以脱水再加水法对酶活性影响较少，脂类组成以磷脂酰胆碱：胆固醇：磷脂酰丝氨酸比值7∶2∶1最好；(4)固定化PAL活性酵母细胞能较好地抵抗人工肠液中胰蛋白酶的水解作用，亦能明显降低苯丙氨酸的浓度。

The pharmacodynamics and therapeutic function of Ganzhixiao decocting prescription to fatty liver as the following:1. Adjust lipometabolism:reducing TC and TG;Decreasing fatty degeneration of liver cell;2. promoting the convalescence of hepatocellular function;3. Anti-lipid peroxide:increasing the the activation of peroxidase, decreasing the content of productsof lipid peroxide.

肝脂消颗粒剂治疗脂肪肝的效应及药效学机制为： 1、调整脂质代谢：使肝酶活性增强，降低血清甘油三脂和胆固醇； 2、减轻肝细胞脂肪变牲； 3、促进肝细胞功能恢复，有效治疗脂肪性肝炎； 4、抗脂质过氧化：提高抗氧化酶活性、降低脂质过氧化产物含量。

A pot experiment was conducted to investigate the effect of soil water on protective enzymes of superoxide dismutase, catalase and peroxidase, and also on membrane lipid peroxidation including malonaldehyde and plasma membrane permeability in pea (Pisum sativum Linn.) leaf during flowering and pod-bearing stages under drought stress and water recovery conditions. Antioxidant ability of pea during flowering and pod-bearing stages was also analyzed.

为探讨不同水分条件对豌豆保护酶系统和膜脂过氧化的影响，采用盆栽人工控水试验方法，模拟干旱胁迫及复水条件，研究了不同水分处理对花荚期豌豆叶片超氧化物歧化酶、过氧化氢酶、过氧化物酶活性以及过氧化产物丙二醛含量和脂膜相对透性的影响，并对花荚期豌豆抗氧化能力进行了综合评价。

The activities of superoxide dismutase, catalase, peroxidase and malonyldialdehyde were determined in hepatopancreas in oriental weatherfish Misgurnus anguillicaudatus exposed to different concentrations 0.025mg Cd(Ⅱ/L, 0.25 mg Cd/L and 2.5 mg Cd/L of Cadmium chloride Cd(Ⅱ to evaluate the effects of cadmium stress on xanthine oxidase and antionxidant enzyme activities.

研究了不同浓度的cd对泥鳅肝脏内抗氧化酶包括超氧化物岐化酶、过氧化氢酶、过氧化物酶活性的影响以及对脂质过氧化指标－丙二醛含量的影响，探讨了在Cd胁迫下，泥鳅肝组织内抗氧化酶活性以及脂质过氧化的变化趋势及其关系。

However, fully consideration of special structure and physiological function of CRP is critical to investigate whether CRP provide protect effect or pathogenic effect in the progression of atherosclerosis. CRP is a member of pentrxins family, which consists of five identical, noncovalently associated 23-kDa protomers arranged symmetrically around a central pore with a 102 A external diameter. Each protomer has a recognition face with a phosphocholine binding site consisting of two coordinated calcium ions adjacent to a hydrophobic pocket. The opposite face of the pentamer is the effector face, where complement Clq binds and Fc receptors are presumed to bind. A cleft extends from the center of the protomer to the central pore of the pentamer. Both faces ofpentamer form a special bi-phase structure: one face is the ligand recognition phase, which can recognize apoptosis cells and enzyme modified low density lipoprotein in which PCh is exposed.

CRP是一种五聚体蛋白，外径为102 A，由5个相同的单体以非共价键结合，形成双面的环形结构，每个单体的配体识别位点或受体结合位点分别位于五聚体两个平面上，分别组成配体识别相和效应器相，从而构成特殊的二相性结构：一面为配体识别相，含有磷酸胆碱(phosphorycholine，PCh)结合位点，能够使CRP识别在病理条件下暴露出PCh的凋亡细胞、酶修饰低密度脂蛋白(enzyme modified low density lipoprotein，E-LDL)等。E-LDL是天然低密度脂蛋白(native Low density lipoprotein，N-LDL)在多种蛋白酶，如胰蛋白酶、神经氨酸酶、胆固醇酯酶等作用下的代谢产物，其主要特点是结构发生改变(N-LDL大小均匀，平均直径250±30 A，E-LDL大小差异极大，直径为100-2000 A)，暴露磷酸胆碱位点，能够被CRP识别；另一面为效应器相，能够与巨噬细胞、单核细胞表面受体FcγRⅡa结合，介导巨噬细胞、单核细胞识别及吞噬凋亡、坏死细胞作用。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。