脂酶

Objective To determine the possible role of hepatic lipase and lipoprotein lipase in the pathogenesis of fatty liver.

目的 探讨肝脂酶和脂蛋白脂肪酶在脂肪肝发病中的作用。

Results hPDLP wasisolated from human periodontium and most of the cells retained their fibroblastic spindle shape. hPDLP can be in-duced into osteoblast-like cells and adipocyte-like cells, and calcium deposition and lipid droplets were detected perspectively.

结果 第1代hPDLP的CD146和STRO-1阳性率分别是27.20%±3.98%和4.23%±4.08%；经矿化诱导可以形成矿化结节，有钙盐沉积；经成脂诱导可见特异性脂滴形成，特异性转录因子过氧化物酶体激活物增生受体2（PPARγ2）和脂蛋白脂酶表达上调。

The last part of this article emphasis on the mechanism of cichory extract N2. Hepatic lipase, NO and xanthine oxidase are observed in this aspect, and gene expression of hepatic lipase is also detected.

本部分研究观察了菊苣提取物 N2 对影响脂质代谢的肝脂酶、尿酸代谢的关键酶黄嘌呤氧化酶、一氧化氮的活性和含量，还从分子生物学角度观察了肝脂酶的基因表达。

The data shoewed that esculetin, resveratrol enhanced LPL expression up to about 1.2 ~3.5 fold compared with the control group. In addition to fibrates, however, no effect on LPL expression by curcumin was observed. We concluded that esculetin and resveratrol enhanced LPL expression on CHO-K1 cell. We hope that we can apply these drugs to mutant form LPL, furthermore apply theses drugs into clinical treatment.

利用药物处理有转染带有完整人类脂蛋白解脂酶启动子和脂蛋白解脂酶cDNA 序列(-1715 ~+1643)质体的CHO-K1细胞，从细胞培养液以及细胞溶解物中发现，除了curcumin之外所有药物都可以使得细胞培养液以及细胞溶解液内的脂蛋白解脂酶活性有1.2至3.5倍的上升，由此结果可知除了curcumin外，esculetin和白藜芦醇以及其他fibrate药物可降低三酸甘油脂血症。

The paper discussed how docosahexaenoic acid regulated transcription expression of lipogenic and lipolytic genes, which included PPARγ(peroxisome proliferators activated receptor γ), SREBP-1c (sterol regulatory element binding protein-1c), FAS, HSL (hormone-sensitive lipase) and TGH.

探讨二十二碳六烯酸对小鼠脂肪组织和肝脏生脂相关基因过氧化物酶增殖物激活受体γ、固醇调节元件结合蛋白－1c基因(SREBP-1c)、脂肪酸合成酶基因，及脂解相关基因激素敏感脂酶基因和甘油三酯水解酶时序表达的影响。

We detected the distribution of lipases in 35 Aeromonas isolates by PCR andphenotypic test using tributyrin as substrate. The positive rates were 100% and 83%,respectively. The lipase activity or associated genes could be detected in the two avirulentstrains, A. hydrophila W1 and A. hydrophila 4332. It suggested that lipase might not be animportant factor in pathogenic mechanism of A.

对本实验室保存的35株气单胞菌分离株进行了脂酶的表型检测和PCR检测，结果分别为83％和100％，特别是嗜水气单胞菌无毒株W1和Ah4332也能检测到脂酶活性或基因，表明脂酶在该菌的致病机制中不是决定性因子。

Which can be used as the body of vitamin B1 coenzyme of many enzymes in the normal human body has an important role in glucose metabolism, it can inhibit the activity of cholinesterase, and choline esterase is an important neurotransmitter, and thus nerve conduction impact; vitamin B2 in the organization by participating in a variety of yellow enzymes constitute a coenzyme, its role in bio-oxidation process in the delivery of hydrogen role in regulating the body's metabolism process; vitamin B6 can also be a variety of enzymes as coenzyme participate in all kinds of amino acid metabolism, promote the absorption of amino acids and protein synthesis, cell growth is necessary for the material, which also promote fat metabolism, involved in neurotransmitter synthesis, hemoglobin synthesis and the impact on the normal reproductive functions such as human body an important metabolic process, Volkswagen Medicine Net: What liver protection effect of vitamin B family?

可作为维生素乙许多酶的辅酶，在正常人体组织中有一个用糖代谢的重要作用，能抑制胆碱酯酶活性，和胆碱脂酶是一个重要的神经递质，神经传导，从而影响；由黄色参与各种酶在组织中维生素B2构成辅酶，其作用在生物氧化氢的作用，调节人体的代谢过程中产程；维生素B6也可以是作为辅酶参与氨基酸代谢的各种酶的品种，促进氨基酸的吸收和蛋白质合成，细胞生长是必要的材料，这也促进脂肪代谢的神经递质合成，血红蛋白合成和参与，如影响人体生殖功能的正常新陈代谢过程中一个重要的，（大众医药网：什么样的维生素B家庭肝脏的保护作用？

The results indicated that the paralysors and excitomotors of calcium channel changed the expression level of lipoprotein lipase, peroxisome proliferators-activated receptor gamma, fatty acid synthetase, and the lipid accumulation, markedly.

结果表明：钙通道阻滞剂和激动剂显著改变了脂蛋白脂酶，过氧化物增殖激活受体γ、脂肪酸合成酶的表达水平，且影响细胞内的脂质蓄积。

He analysis of the category and function of TCB stress inducible proteins showed that different groups of proteins were induced by 5 mg L^(-1) TCB stress. They are detoxification enzymes (including esterase, aldo/keto reductases, and glutathione S-transferase), cell wall compound metabolism related enzymes (including UDP-glucose protein transglucosylase and GDP-mannose 3,5-epimerase 1), phytohormone metabolism and regulation related enzymes or proteins (including aci-reductone dioxygenase 4, beta-glucosidase, two members of pathogenesis-related proteins from family 10), primary and secondary metabolism regulative enzymes (including translational elongation factor Tu, cytosolic orthophosphate dikinase, triosephosphate isomerases, alanine aminotransferase, and isoflavone reductase).

CB胁迫能诱导根系内不同类型蛋白质的表达，它们是：解毒酶（包括脂酶、醛／酮还原酶、谷胱甘肽－硫转移酶），细胞壁物质代谢相关酶（包括蛋白转葡萄糖基酶、GDP-甘露糖－3，5-异构酶1），激素代谢或调节相关酶（包括酸式－还原酮二加氧酶、β-葡萄糖苷酶、病程相关蛋白家族10中的2个不同蛋白），原初或次生代谢相关酶（包括转录延长因子、细胞质磷酸丙酮酸双激酶、磷酸丙糖异构酶、丙氨酸氨基转移酶和异黄酮还原酶）。

This experiment was made to investigate the changes of lipopro tein li pase and hepatic lipase activity and their effects on gallstone formati on in rabbit model in which the stones were induced by high cholesterol diet.Act ivities of plasma LPL and HL were determined; other data including concentratio n of plasma lipoprotein cholesterol, concentration of bile cholesterol and bile acids were also obtained.

为研究肝脂酶及脂蛋白脂酶在胆固醇结石成石过程中的变化及其对成石的影响，采用高胆固醇膳食诱发兔胆囊胆固醇结石模型，观测对照组及高胆固醇膳食1、2 、3、4周组动物血浆脂蛋白脂酶、肝脂酶活性、血浆脂蛋白胆固醇及胆汁中甘氨胆酸、甘氨脱氧胆酸、胆固醇的变化。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。