脂过多症

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。