脂质体的

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，"PMN-EC"相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

RESULTS: RAD decreased superoxide anion production of RPN stimulated by formyl Met Leu Phe and phorbol 1,2 myristate 1,3 acetate, and inhibited hydrogen...

迷迭香酸抑制中性粒细胞呼吸爆发和脂质过氧化及通过降低细胞内钙离子浓度而抑制溶酶体酶的释放

The comparative transcript profiles between OP and OR rats reveal some differentially expressed genes involved in lipids metabolism, ketone body production, blood pressure regulation and adipoctyes differentiation processes.The combined strategy of metabonomics and transcriptomics provides comprehensive information of metabolic characters of obesity and corresponding mechanisms to obese-related metabolic disorders from a systematic view, e.g.

高脂饮食喂养建立的OP大鼠体内的整体代谢特征与OR大鼠不同，具体包括：交感神经系统活性、能量代谢、脂肪酸代谢、氨基酸代谢以及肠道菌群结构等；OP和OR两种表型的转录组学比较也揭示了部分参与脂质代谢、酮体生成、血压调节和脂肪细胞分化等调控过程的基因存在差异性表达。

Therefore, CRP could mediate E-LDL participating in the early stage of atherogenesis. CRP is an ancient conserved protein whose initial role as a pattern recognition molecule may have been to defend against bacterial infections, but whose present biological role appears quite complex. CRP is protective against a variety of bacterial infections and inflammatory stimuli as an opsonin. It is likely that the activity of CRP in humans is either pro- or anti-inflammatory is dependent on the context in which it is acting.

由于CRP的识别相可以结合被暴露出磷酸胆碱结构的E-LDL，形成E-LDL／CRP复合体，而内皮细胞表面能以高亲和力识别CRP的配体相，从而CRP-相性结构具有结合E-LDL，被内皮细胞捕获，引起脂质沉积和激活补体、触发炎症反应的可能性，这样可以解释早期动脉粥样硬化为何同时存在E-LDL、CRP、补体，而这三种物质在同时、同地出现绝非一个巧合。

METHODS AND RESULTS: Using both primary peritoneal macrophages and studies in advanced atheromata in vivo, we introduce signal transducer and activator of transcription-1 (STAT1) as a critical and necessary component of endoplasmic reticulum stress/type A scavenger receptor-induced macrophage apoptosis.

方法和结果：通过使用原代腹膜巨噬细胞研究在体脂质斑块，我们引入信号转导子和转录激活子-1(STAT1)，作为内质网应激/A型清道夫受体诱导的巨噬细胞凋亡中关键和必要组分。

There has been the report such as the male agaric fruiting body can restrain the tumour, gallbladder fibrosis, lipide overoxidation and so on. But both here ahd abroad have no report about male agaroc mycelium amylose could decrease bllod pressure and protect liver fuction.

有关桑黄子实体多糖抗肿瘤、抗肝纤维化与抗脂质过氧化作用活性及桑黄菌丝体多糖抗肿瘤活性的研究已有报导，但国内、外有关桑黄菌丝体多糖的降血糖、保护肝功能作用等生物活性的研究至今尚未见报告。

Objective To investigate the potential pathogenicity of Mycoplasma penetrans (M. penetrans), and to study nitric oxide production and cell prolification in lipid-associated membrane proteins-stimulated mouse macrophages.

目的 检测穿透支原体脂质相关膜蛋白能否诱导小鼠巨噬细胞产生一氧化氮及其对细胞增殖的影响，以了解穿透支原体潜在的致病性。

BR is embedded in the purple membrane and organized in trimeric unit arranged in a hexagonal twodimensional crystalline lattice, there are about 30 lipid molecules surrounding a BR trimer.

BR分子在紫膜中以三聚体的形式存在，并形成二维的六角型晶格，每个三聚体周围约有30个脂质分子。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活，ICAM-1表达升高，与被激活的PMN表面表达的LFA-1相结合，&PMN-EC&相互作用加剧，一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍；另一方面粘附的PMN过度吞噬或激活，当白细胞吞噬的颗粒不能被封闭隔离，连同细胞内的酶被释放出来，其中的PMN-elastase能够降解细胞基质中各种成分，水解多种蛋白，加重胰腺的毛细血管内皮细胞和腺泡的损伤；释放的溶酶体酶使组织蛋白水解，产生的不饱和脂肪酸引发脂质过氧化方应，破坏细胞膜的结构和功能；释放的炎性细胞因子，激发其他的免疫细胞的功能，导致进一步的组织损伤和坏死，加重SAP的病理损伤，最终导致休克、脓毒血症及多器官功能障碍等严重后果。

The cell in acidic situation presented a degenerative chang-ment,such as an increased lipid drop and empty cavity in the cell plasma,a py-knotic nuclei,the dilatation of the endoplasmic reticulum and Golgi saccules,mi-tochondrial swelling the number of ribose decrease,and the ribose dissociated inthe plasma,a lot of swallowing cavity,the fibric material decreased accompany-ing with the acid being stronger.

随培养基pH逐渐下降，上述过程因受酸性阻抑而延缓，细胞增殖速度也受影响，处于酸性环境中的软骨细胞呈退行性变化，表现为细胞浆内脂质颗粒与小泡增多、细胞核皱缩、核仁浓染、内质网线粒体膨胀、核糖体数目减少，且与粗面内质网结合的少，游离在胞浆中的多。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。