脂质体

As the new medication-adjuvant,liposome has been widely applied in medication technology.

尽管脂质体这种新技术在生物领域内具有极其广阔的应用前景，但脂质体在该领域的研究应用中存在着较多的技术难题。

Methods: Lecithin and the sucrose ester-phospholipids liposome were prepared using the ethyl ether injection method by mixing sucrose ester with lecithin, sphingomyelin and cholesterol according to different lipids ratio.

按不同比例将乙酸异丁酸蔗糖酯与卵磷脂、鞘磷脂和胆固醇混合，溶于乙醚中，然后注入pH7.2的PBS缓冲液中，制成卵磷脂脂质体及蔗糖酯－卵磷脂脂质体。

Liaoning Medical University, Jinzhou 121001 China）Abstract:Objective To study the distribution and liver targeting of glycyrrhetinic acid derivatives (stearin glycyrrhetinic acid ester-3-O-galactosidase, Gal-GAOSt) modifying norcantharidin liposomes (Gal-GAOStNC-LP) in rats.

目的 研究甘草次酸衍生物（甘草次酸硬脂醇酯-3-O-半乳糖苷，Gal-GAOSt）修饰去甲斑蝥素脂质体(Gal-GAOStNC-LP)在小鼠体内的分布及肝靶向性。方法利用薄膜分散法制备甘草次酸衍生物修饰去甲斑蝥素脂质体后，经小鼠尾静脉给药，采用HPLC法检测去甲斑

Objective: Novel liposomes composed of hydrogenated soybean phosphatidylcholine and soybean phosphatidylcholine was prepared to encapsulate total alkaloids from seed of Strychnos nux-vomica. The pharmaceutical properties of the novel liposomes were compared with corresponding HSPC or SPC liposomes.

中文摘要：目的：制备了以氢化大豆磷脂和普通大豆磷脂为膜材的马钱子总生物碱复合磷脂脂质体，并与相应的单一磷脂脂质体比较药剂学性质。

Zetasizer was used to determine the size of liposomes and the entrapment efficiency was determined with centrifugal ultrafilter.

采用Zetasizer粒径测定仪测定脂质体粒径；采用离心超滤法测定脂质体的包封率。

Cholesteryl hexadecyl ether is synthesized and labeled with tritum to trace the biofate of liposomes.

合成胆固醇的十六烷基醚，并用〓标记，掺入脂质体以示踪脂质体在体内的分布、代谢情况。

Aim:To observe the therapeutic effects of liposomeencapsulated adriamycinadministered into the hepatic artery for hepatoma in rats fand compare it with that of adriamycin solution and ADM plus blank liposome.

目的：观察阿霉素脂质体经肝动脉给药对大鼠肝肿瘤的疗效，并与阿霉素水溶液及阿霉素加空白脂质体相比较。

The allograft was harvested at 6h posttransplantation. Scrambled ODN group: The donor kidney was stored for 6h in ECs containing 1 u M Liposome/scrambled ODN complexes under hypothermal and hypoxia condition, then the donor kidney was transplanted into a SD recipient, and at 6h posttransplantation the allograft was harvested.

五、试验分四组：(1) Control组假手术组，Wister大鼠麻醉后，开腹后，即将伤口缝合，6h后切取左肾；(2) ECs组供肾经ECs(不含脂质体/ODN复合物)低温缺氧保存6h，移植到受体大鼠6h后切取移植肾；(3)deeoy onN组供肾经含1 pM的deeoy onN脂质体复合物的ECs 低温缺氧保存6h，移植到受体大鼠6h切取移植肾；(4)sc~。

Results In Vero cell system,under lucifugal and illumination conditions,fullerene C60 has direct virucidal activity and infection block effect,but it does not has any multiplication inhibition action to HSV-1F strain.

以逆相蒸馏法合成了富勒烯脂质体，用药物对病毒所致细胞病变的抑制实验以及病毒的空斑减数实验，观察C60脂质体对HSV-1F株的直接杀灭、感染阻断及增殖抑制作用。

Electron microscope observations showed that the liposome suspension was heterogeneous and the particle size ranged from 20 nm to 700 nm with a average diameter of 163 nm. The vesicles showed unilamellar and multilamellar structure which consisted of several concentric bilayers.

电镜观察表明，该脂质体多呈球形的单层或多层结构，脂质体粒径分布均匀，粒径范围20-700 nm，平均粒径163 nm，主要粒径分布位于50-200 nm(84.80%)。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。