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In order to understand the mechanism of anti-inflammatory effect of PA and carvacrol, the superoxide dismutase, glutahoine reductase, glutahoine peroxidase activities in liver and malondialdehyde , cyclooxygenase 2 (COX-2), tumor necrosis factor-α levels were eveluated. Also observed inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) expression and the pathological histology in λ-carrageenan induced paw edema in mice.

本研究首先以醋酸扭体试验评估左手香水抽提物及其活性成分香芹酚是否具有镇痛效果,以福马林舔足试验辨别其镇痛作用是在周边或是中枢,再以λ-角叉菜胶诱导小鼠足跖肿胀试验探讨其抗发炎作用,并分析其肝脏组织中的超氧歧化酶、麸胱甘肽还原酶、麸胱甘肽过氧化酶活性、发炎足跖组织中的脂质过氧化指标产物丙二醛、肿瘤坏死因子-α及环氧化酶-2之含量变化,观察诱导型一氧化氮合成酶及环氧化酶-2之蛋白质表现量,并将肿胀足跖做病理切片观察之,以探讨左手香水抽提物及香芹酚之抗发炎机转。

The Thiobarbituric acid-reactive substances assay is a sensitivity HPLC assay that measures a chromogen that is produced by the reaction of thiobarbituric acid with malondialdehyde, which is an endproduct of lipid peroxidation.

硫巴比妥酸反应物分析,利用HPLC的灵敏特性分析硫巴比妥酸与丙二醛反应所产生的发色体,其为内生性脂质过氧化物。

RESULTS: RAD decreased superoxide anion production of RPN stimulated by formyl Met Leu Phe and phorbol 1,2 myristate 1,3 acetate, and inhibited hydrogen...

迷迭香酸抑制中性粒细胞呼吸爆发和脂质过氧化及通过降低细胞内钙离子浓度而抑制溶酶体酶的释放

These genes were involved in pathways of lipids metabolism, ketone body production, enzymatic and transcriptional regulation, most of which were consistent with results of metabonomic investigation.

肥胖易感与肥胖抵抗大鼠转录组学比较发现两组动物肝脏中有近80种基因在转录水平表现出显著差异(≥1.5倍),差异表达的基因主要涉及到脂质代谢、酮体生成、酶调节和转录调节等代谢通路。

Methods Mouse macrophages were stimulated with Mpe LAMPs to analyze the activitation of NF-κB, and the effect of pyrrolidine dithiocarbamate, an inhibitor of NF-κB, on NF-κB activation was also studied by indirect immunofluorescence and western blot.

用从穿透支原体中提取的脂质相关膜蛋白刺激小鼠巨噬细胞,经Western blot和间接免疫荧光等方法检测NF-κB是否被激活,以及NF-κB抑制剂PDTC对NF-κB活性的影响。

AIM :To investigate the changes of glutamate transporter function,superoxide dismutase activity and malondiadehyde content in rats with injury of cerebral ischemia-reperfusion and antagonistical effect of dexamethasone.

目的:探讨大鼠脑缺血-再灌注损伤时脑组织谷氨酸转运体功能及超氧化物岐化酶活性、脂质过氧化物丙二醛含量变化及地塞米松对其的影响。

There has been the report such as the male agaric fruiting body can restrain the tumour, gallbladder fibrosis, lipide overoxidation and so on. But both here ahd abroad have no report about male agaroc mycelium amylose could decrease bllod pressure and protect liver fuction.

有关桑黄子实体多糖抗肿瘤、抗肝纤维化与抗脂质过氧化作用活性及桑黄菌丝体多糖抗肿瘤活性的研究已有报导,但国内、外有关桑黄菌丝体多糖的降血糖、保护肝功能作用等生物活性的研究至今尚未见报告。

Objective To investigate the potential pathogenicity of Mycoplasma penetrans (M. penetrans), and to study nitric oxide production and cell prolification in lipid-associated membrane proteins-stimulated mouse macrophages.

目的 检测穿透支原体脂质相关膜蛋白能否诱导小鼠巨噬细胞产生一氧化氮及其对细胞增殖的影响,以了解穿透支原体潜在的致病性。

BR is embedded in the purple membrane and organized in trimeric unit arranged in a hexagonal twodimensional crystalline lattice, there are about 30 lipid molecules surrounding a BR trimer.

BR分子在紫膜中以三聚体的形式存在,并形成二维的六角型晶格,每个三聚体周围约有30个脂质分子。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,&PMN-EC&相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。