脂质体

Liposomal entrapment efficiency of urokinasein by MREV is as high as 65％, which is not evidently influenced by incorporation of phospholipid derivatives such as DSPE-PEG-RGDS and Stearyl RGDS.

改良反相蒸发法在磷脂相转变温度以下制备脂质体以提高包封率的效应在尿激酶上得到了很好的体现。

Aim To prepare sterically stabilized liposomes modified with chimeric TNT-3 monoclonal antibody （chTNT-3） and investigate their immunoreactivity and in vitro targeting.

目的 研究人鼠嵌合抗肿瘤细胞核单抗（chTNT-3）-空间稳定脂质体的制备方法、免疫活性及体外靶向性。

Followed two-compartment model, the biological half-life of chTNT-3-SL and (chTNT-3/B + SAv-SL) in rats was longer than that of free doxorubicin but shorter than sterically stabilized liposomes.

结果表明，两种主动靶向脂质体给药系统与固定Raji细胞的结合量均显著高于阴性对照组(P＜0.001)。

The method of which lipofectin mediated gene transfected cornea of rabbit by subconjunctival injection is practicable and secure.

脂质体介导基因经球结膜下注射转染兔眼角膜是可行而且是安全的。

Methods:Human CD80 cDNA was transfected into B16 melanoma cells by lipofectin-mediated gene transfer before the expansion of tumor cells were tested by MTT method in vitro;C57BL/6 mice were inculated subcutaneously either mock-transfected B16 cells (B16-neo)or CD80-transfected B16 cells (B16-CD80),then the latency,survival times and tumor mass growth were investigated.The lymphocytes were examined for both proliferation indices and specific cytotoxic activity by MTT method and improved LDH-releasing method,after syngenic Mixed Lymphocyte tumor cultures.

通过脂质体介导将CD80基因导入小鼠黑色素瘤B16细胞后，利用SABC法检测CD80的表达；MTT法测定肿瘤细胞体外增殖能力；将肿瘤细胞接种至同源小鼠皮下后观察成瘤期、荷瘤小鼠存活期及肿瘤结节生长速度；在同源淋巴细胞肿瘤细胞混合培养后，通过测定淋巴细胞增殖指数和CTL杀伤活性检测肿瘤细胞的免疫原性。

In addition, chitosan-coated liposomes could protect insulin from tryptic digestion, and the protective action was enhanced with increasing the molecular weights of chitosan, and there was not obvious correlation between the protective action and the concentrations of chitosan.

在胃蛋白酶溶液中，用壳聚糖包覆胰岛素脂质体对胰岛素有一定的保护作用，且随壳聚糖的分子量和浓度的增加而增强。

TMC-coated liposomes could reduce peptic and tryptic digestion on insulin, and enhance enteral absorption of insulin.

CEC包覆胰岛素脂质体均具有一定的降血糖作用，这种作用随CEC浓度增加而增加。

The liposomes were uniform,unilamellar particle with effective diameter of 106 nm and entrapment efficiency of 69.20%.

来氟米特脂质体呈均一单型，有效粒径106 nm，包封率69.20%。

The release property of small unilamellar vesicles coated with the copolymer was studied at 25℃ by using 5(6) carboxyfluorescein 5(6 CF as a water soluble marker.

以5（6）－羧基荧光素（5（6）－CF）为水溶性标记物，研究了共聚物包覆的小单层脂质体（smalunilamelarvesicles，SUV）在室温25℃时的释放行为。

Preparation and exosyndrome of liposomal Gd-DTPA 1.1 Preparation small unilamellar vesicles were prepared by combining 0.92 g of distearoylphosphatidylcholinc with 23 mL of distilled watcr.

Gd-DTPA脂质体的制备和表征 1.1制备工艺精密称取一定量二硬脂酰磷脂酰胆碱乙醇胺溶于双蒸水中，置于恒温磁力搅拌器内，在69～72℃恒温条件下超声分散1小时，取一定量Gd-DTPA溶液、蒸馏水和无水乙醇与上述产物混合，获得半透明胶体状物，在室温下过夜，第二天在69～72℃恒温条件下水浴孵化1小时，同时用低流速氮气吹拂液体表面除去有机溶剂无水乙醇。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。