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On MDA generation spontaneously in homogenates of liver, we used in vitro lipid peroxidation model.

在CCl_4诱导的肝脂质过氧化模型中,各组挥发油与阴性对照相比有极显著的(P<0.01)抑制作用。

The protein content, activity of SOD and GSHPX were measured in liver homogenates.

脂质过氧化物歧化酶及谷胱甘肽过氧化物酶活性,并观察肝组织学变化。

RESULT: In vitro,the IC_(50) of Que of inhibiting the production of lipid peroxides in homogenates from rat heart,brain,and CCl_(4) damaged liver in mice and H_(2)O_(2) induced hemolysis is 0.4×10~(-4),0.2×10~(-4),0.5×10~(-4),0.3×10~(-4) mol/L,separately,while that of TP is 0.7×10~(-4),7.8×10~(-4),1.1×10~(-4),0.6×10~(-4) mol/L,separately.

结果 :在体外,Que和TP均可剂量依赖性地抑制Fenton反应导致的大鼠心、脑匀浆和CCl4毒化小鼠肝匀浆中过氧化脂质的生成和H2 O2 诱导的红细胞溶血:Que的IC50 分别为:0 4× 10 -4,0 2× 10 -4,0 5× 10 -4,0 3× 10 -4mol/L ;TP的IC50 分别为:0 7× 10 -4,7 8× 10 -4,1 1×10 -4,0 6× 10 -4mol/L。

The apple polyphenol extracts had stronger reducing capacity, antioxidant activity on lipid-peroxidation, and scavenging effects on hydroxyl radical, superoxide anion radical and nitroso than ascorbic acid at the same concentration.

按照以上工艺制备的苹果多酚提取物具有较强的还原能力和抗脂质过氧化活性,并对羟自山基、超氧阴离子自由基及亚硝基具有很强的清除作用,且优于同浓度的维生素C。

The transient transfection efficiency was measured by flow cytometry. The stable transfected cells were screened by G418. Results Electrotransfection had the highest transient transfection efficiency (56.8%), with the most masc clones of stably transfection and the least time taken to form big masc clones (20 days). Cationic polymer mediated transient transfection had the lowest efficiency (1.7%), with the least masc clones and the longest time taken to form the big masc clones (30 days). Cationic liposome transfection had a transient transfection efficiency of 39.9% and took 25 days to form the big masc clones.

结果 电转染有最高的瞬时转染效率(56.8%),稳定转染得到的阳性克隆最多,且从细胞筛选到扩增至得到阳性大克隆所用的时间也最少(约20d);用阳离子聚合物瞬时转染率低(1.7%),稳定筛选同样可以得到阳性大克隆,但是数量很少且从细胞筛选到扩增至阳性大克隆所用的时间也最多(约30d);阳离子脂质体转染效果居中,瞬时转染率为39.9%,从细胞筛选到扩增至得到阳性大克隆所用的时间约25d。

Experimental Center of National Level One, Hubei Traditional Chinese Medica l College, Wuhan 430061)Abstract To investigate the protective effects of Jiaweisinisa n on acute liver injury induced by intraperitoneal injection of D-ga lac-tosamise, serum superoxide dismutase, malondialdehyde , glutathioe contents were measured. The pathological changes of liver wer e observed simultaneously. The results showed that JWSNS could decrease serum MD A content, but increase serum SOD and GSH activities in acute liver injury induc ed by D-GalN. It was also found that JWSNS could alleviate the degeneration and necrosis of the hypatocytes.

为研讨加味四逆散防治肝损伤的作用机理,通过动物试验,先用加味四逆散预防给药,再采用D-氨基半乳糖造成大鼠急性肝损伤模型,然后检测大鼠血清超氧化物岐化酶、丙二醛、还原型谷胱甘肽水平,同步观察该方对急性肝损伤大鼠体内脂质过氧化反应及肝脏病理改变的影响,结果表明该方可明显升高大鼠血清SOD、GSH水平,降低MDA水平,肝脏病理学检查亦表明该方使肝细胞变性坏死程度减轻。

Aims/hypothesis The nuclear receptors, including nuclear receptor subfamily 1, group H, member 3 (NR1HR, also known as liver X receptor ), are sensors of cholesterol metabolism and lipid biosynthesis that have recently been proposed as insulin sensitisers.

目的/假设:核受体,包括核受体亚家族1,群H,3号成员(NR1HR,也被称作肝X受体LXR),是胆固醇代谢和脂质合成的感受器,最近被认为是胰岛素增敏剂。

Aims/hypothesis The nuclear receptors, including nuclear receptor subfamily 1, group H, member 3 (NR1HR, also known as lier X receptor ), are sensors of cholesterol metabolism and lipid biosynthesis that hae recently been proposed as insulin sensitisers.

目的/假设:核受体,包括核受体亚家族1,群H,3号成员(NR1HR,也被称作肝X受体LXR),是胆固醇代谢和脂质合成的感受器,最近被认为是胰岛素增敏剂。

The same dosage of TP and Vit C had remarkable inhibitory effects on the CCl4 induced liver free radical injury,but there was no significant difference between the two groups.

在CCl4诱发肝自由基损伤体系中,TP和Vit C对脂质过氧化均有明显的抑制作用,但两者之间无显著差异。

Objective To explore the effects of Baogan Jiedu Granule on lipid peroxidation of free radicals in acute liver injury mice induced by tripterygium glycosides.

目的 探讨保肝解毒颗粒对雷公藤多苷致急性肝损伤小鼠自由基脂质过氧化反应的影响。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。