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Because the cell membrane is lipoid, lipid-soluble drugs diffuse more rapidly than relatively lipid-insoluble drugs.

由于细胞膜为类脂质,脂溶性药物的扩散比相对的非脂溶性药物更快些,小分子的透膜速度也要比大分子快。

Because the cell membrane is lipoid, lipid-soluble drugs diffuse more rapidly than relatively lipid-i oluble drugs.

由于细胞膜为类脂质,脂溶性药物的扩散比相对的非脂溶性药物更快些,小分子的透膜速度也要比大分子快。

Objective The differences were researched among the effects of A,Nerinifolium Bak extract from three areas Baoding,Bozhou and Dingzhou on reducing lipoid content in serum.

目的 研究 3产地长梗薤白提取物降脂作用的差异。方法利用家兔高脂血症模型,研究3产地 ANBE的脂质调节作用。

On hyperlipemia show that the pigment could reduce the serum TC, TG, LDL-C concentrations, increase serum and liver T-AOC, GSH-PX activities, decrease liver MDA content significantly (P<0.05). The pigment of Lycium ruthenicum Murr. can inhibit the increase of blood lipids level and increase antioxidant activity in mice with hyperlipemia.

高脂血症预防实验显示,PLR可降低小鼠血清总TC和TG、LDL-C的含量,升高血清和肝组织T-AOC、GSH-PX活性,显著降低肝组织MDA含量(P<0.05),说明黑果枸杞色素对高脂血症小鼠血脂水平升高和脂质过氧化均有一定抑制作用。

Inaddition,we extract total RNA from cultural U251 cell of humanglioma,make coding gene extron amplification of TfR through ReverseTranscription-Polymerase Chain Reaction,construct expressionplasmid of pCDNA3.1-TfR after digestion of enzyme andconjunction,do transfection to U251 cell by liposome afteridentification,cause excess expression,detect the efficiency of transientexpression of TfR protein by pEGFPN1-TfR, sieve positive cell ofpCDNA3.1-TfR through G418, choose positive cell clone, detect theexpression of TfR in anteroposterior period through Western blot,FCM,cell immunochemistry and mRNA through RT-PCR, identify the effect of transfection.

另外,培养人脑胶质瘤U251细胞,进行细胞总RNA抽提,运用RT-PCR方法进行TfR基因的完整编码区外显子的扩增,经过酶切、连接后构建pCDNA3.1-TfR的表达质粒,鉴定正确后按脂质体转染方法转染人胶质瘤U251细胞,使其过量表达,通过pEGFPN1-TfR检测其瞬时转染的效率;用G418对稳定表达pCDNA3.1-TfR的细胞进行筛选,挑选阳性细胞克隆,运用Western blot、流式细胞检测技术和细胞免疫化学以及mRNA半定量的方法检测TfR在转染前后的表达水平,鉴定转染的效果。

The last part of this article emphasis on the mechanism of cichory extract N2. Hepatic lipase, NO and xanthine oxidase are observed in this aspect, and gene expression of hepatic lipase is also detected.

本部分研究观察了菊苣提取物 N2 对影响脂质代谢的肝脂酶、尿酸代谢的关键酶黄嘌呤氧化酶、一氧化氮的活性和含量,还从分子生物学角度观察了肝脂酶的基因表达。

The pcDNA〓-apoE〓 plasmid was transfected to SK-N-SH Neuroblastoma cell by liposome. It could be screened by G〓. The immunohistochemical assay was shown that neuroblastoma cell transfected by pcDNA〓-apoE〓 expressed the recombinant apoE protein. The intracellular expressed recombinant protein could inhibit the death of neuroblastoma cell induced by beta amyloidal peptides 25-35 fragment.

用pcDNA〓—apoE〓真核表达载体与脂质体共转染神经成纤维胶质瘤细胞,用G〓选择压力筛选,细胞免疫荧光检测表明,pcDNA〓—apoE〓转染的神经成纤维胶质瘤细胞表达了apoE〓重组蛋白,这种内源性的apoE〓重组蛋白对25μM Aβ25—35多肽诱导的神经成纤维胶质瘤细胞的死亡具有拮抗作用。

Aim To investigate the possible interaction of cholesteryl ester transfer protein level with the lipid transport between the lipoproteins.

目的分析不同高脂血症人群血清胆固醇酯转运蛋白水平及其对血浆各脂蛋白间脂质转运的调节作用。

The coturnix artherosclerosis model was established by feeding with high-fat diet (1% cholesterol, 14% lard, 6% bean oil) and treating it with Yizhikang simultaneously, observing whether serum TC, TG, LDL-c, HDL-c, VLDL-c, liver lipidoses and AO artherosclerotic plaque were resulted at.

用高脂饲料(1%胆固醇,14%猪油,6%豆油,剩余加入基础饲料)喂养复制鹌鹑动脉粥样硬化模型并同时给药,观察益脂康对其血清TC,TG,LDL-c,HDL-c,VLDL-c,肝脏脂质沉积和主动脉粥样硬化斑块形成的影响。

Encapsulated psoralen were evaluated by dialyzation using psoralen gel as the control. Changes of liposome????encapsulated psoralen and release rate were detected during a 3????week storage at 4 ℃ for evaluating the stability of the liposomal formulation.

以同浓度的补骨脂素凝胶为对照,用透析法检测补骨脂素脂质体凝胶的体外释药模式,并对其在4 ℃下贮存3周的释药稳定性进行研究。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。