脂血

Recombinant plasmid pSVH 7 DNA of avian influenza virus H7 subtype heamagglutinin gene was encapsulated with DC-chol/DOPE liposomes and PC/chol/SA liposomes separately. Two-week old SPF chickens were intramuscularly inoculated with 50 μ g/0.2ml of the liposome entrapped PSVH 7 DNA. Four-weeks later, each chicken was challenged with 0.1ml 〓 AIV . One week after the challenge, the secretion of the cloacas was collected and transfected to chicken embryos to isolate the virus. The virus was isolated from 6/6 of the control group, 1/6 of the naked DNA group, 1/6 of the PC/chol/SA entrapped DNA group and 0/6 of the DC-chol/DOPE liposome entrapped group. The HI antibody titers (log2) of the four groups were 6. 83±0.98, 7. 0±1. 26, 7. 83±1. 17 and 8. 00±0.89 respectively 1-week after challenge, and 8. 5±0.55, 8. 17±0.82, 8. 68±0.45 and 9. 33±0.54 respectively 2-week after challenge. The results showed that inoculation of liposome entrapped DNA significantly enhanced resistance to virosis in animals.

将含禽流感病毒H7亚型血凝素基因的重组质粒pSVH7用DC-chol阳离子脂质体和胆固醇／卵磷脂／十八胺脂质体包裹，免疫2周龄SPF鸡，4周后用同型禽流感病毒进行人工感染，1周后采集泄殖腔分泌物分离病毒，结果未免疫组6／6分离到病毒，裸质粒DNA免疫组1／6分离到病毒胆固醇／卵磷脂／十八胺脂质体包裹DNA免疫组1／6分离到病毒，DC-chol脂质体DNA免疫组没有分离到病毒（0／6）：人工感染后1周各组的HI抗体（Log2）分别为6.38±0.98，7.00±1.26，7.83±1.17，8.00±0.89，2周后为8.50±0.55，8.67±0.82，8.68±0.45，9.33±0.52，脂质体包裹组在同期均高于未免疫组和裸DNA免疫组，表明脂质体包裹质粒DNA免疫动物后，能增加动物对病毒感染的抵抗力和反应能力。

The data shoewed that esculetin, resveratrol enhanced LPL expression up to about 1.2 ~3.5 fold compared with the control group. In addition to fibrates, however, no effect on LPL expression by curcumin was observed. We concluded that esculetin and resveratrol enhanced LPL expression on CHO-K1 cell. We hope that we can apply these drugs to mutant form LPL, furthermore apply theses drugs into clinical treatment.

利用药物处理有转染带有完整人类脂蛋白解脂酶启动子和脂蛋白解脂酶cDNA 序列(-1715 ~+1643)质体的CHO-K1细胞，从细胞培养液以及细胞溶解物中发现，除了curcumin之外所有药物都可以使得细胞培养液以及细胞溶解液内的脂蛋白解脂酶活性有1.2至3.5倍的上升，由此结果可知除了curcumin外，esculetin和白藜芦醇以及其他fibrate药物可降低三酸甘油脂血症。

PON has been shown to be closely associated with lipometabolism by protecting LDL from oxidative modification,decreasing level of ox-LDL and destroying lysophospholipid of ox-LDL .

对氧磷酶由355个氨基酸组成，它与高密度脂蛋白中的载脂蛋白结合，能保护低密度脂蛋白免受氧化修饰，降低体内氧化型低密度脂蛋白水平，并且能破坏氧化型低密度脂蛋白中的溶血磷脂，与脂代谢有密切关系。

Low-fat diet was given to those patients. The changes of total cholesterol,high-density lipoprotein,low-denstiy lipoprotein,triglyceride,aproprotein A, aproprotein B, creatinine, glutamic oxalacetic transaminase, glutamic pyruvic transaminase were measured before and after 1,3,6,12 months of Simvastatin therapy(10mg,qd).

所有患者均采取低脂饮食，测定患者血总胆固醇、高密度脂蛋白、低密度脂蛋白、甘油三酯、载脂蛋白A、载脂蛋白B、肌酐，谷草转氨酶及谷丙转氨酶等各参数数值；然后给予辛伐他汀10 mg，每晚一次口服，测定用药后1，3，6，12个月后以上各参数值的变化。

No difference were found for daily milking yield for among three groups also no difference for milk fat percentage between one fourth wild and domestic yak,but the milk fat percentage of semiwild is lower than that of o...

经q检验，3组的日均挤乳量和1／4野血牦牛与家牦牛的乳脂率均差异不显著（P＞0.05），而1／2野血牦牛因野性较大，难以挤净含脂较高的二奶，以致乳脂率低于其它两组。

Results Xuezhikangcould markedly decrease the level of triglyceride and serum total cholesterol in elderlypatients,especially triglyceride.Its effects were the same as other tatin drug.Afterobserving 8 weeks,no side effects were found in clinic and biochemistry.

结果 老年高脂血症患者服用血脂康，对降低甘油三酯和胆固醇疗效均显著，尤其是甘油三酯，与其它他汀类药物相似，未发现有明显的临床和生化毒副作用。

Tibolone plus "Geng'an ning" may protect endothelial cell against hypercholesterolaemia damage to arterial wall.

替勃龙联合补肾中药更安宁治疗能保护血管内皮细胞，对抗高脂血症对动脉管壁的损伤。

Methods: Wistar rats used were divided into normal control group an d hyp erlipemia group. The morphological changes of er ythrocytes were observed by SEM, and classified and counted.

Wistar大鼠分为正常对照组和高脂血症组，利用扫描电镜观察红细胞形态改变并计数分类。

Vascular obstruction of the microcirculation may be caused by fat emboli, related to hyperlipidemia associated with alcoholism, steroid therapy, SCD, and nitrogen bubbles in decompression sickness.

血管阻塞的微循环可能造成的脂肪栓子，与高脂血症与酗酒，类固醇治疗，猝死，氮泡沫减压病。

The animal model of this method system have, the characteristics of the high fat, high leptin, high Ins, and match with the characteristic of clinical and the pathologic of simple obesity. This studies showed: The acupuncture can obviously reduce the vaule of intaking food and water of the fat rats, and lower the body weight and fat; The acupuncture can urge the diameter, area, physical volume of white fat cell contract, Brown fat tissue of fat rat group surroundings vascular containing large quantity of white fat cell, the acupuncture group was less. this showed: The acupuncture enhanced the white fat cell metabolism, and promotesed the white fat cell to convert to brown fat cell; The frequency of spontaneous electric of nerve cell of pvn of the fat rat is high, the acupuncture counld depress the spontaneous electric of nerve cell of pvn, This showed: the acupuncture can depress the appetite passing to adjust function of pvn nerve; The monoaminergic neurotransmitter of inside of the fat rat brain is disfunction, the acupuncture can rectify this disfunction, and adjust level of 5-HT, and affect appetite, and improve metabolism; The level of leptin and Ins of fat rat increased high, The level of it of acupuncture group decreased, compared with the fat group p.001, This showed: the fat rats have the defeat of leptin and Ins in the body, The acupuncture can lowering this defeat, The level of leptin and Ins of the fat rat in the brain is less than the normal group, The level of leptin of the acupuncture group is high than the fat group, This showed: the acupuncture can increase the transportation of leptin from blood to brain.

本方法所制肥胖大鼠模型具有高体重、高脂、高leptin和高Ins血症的特点，符合人类单纯性肥胖病的临床和病理特征；实验研究显示：针灸能明显减少肥胖大鼠的摄水、摄食量及降低其体重、体脂；针灸能促使白色脂肪细胞直径、面积、体积缩小，减少肥胖大鼠棕色脂肪组织血管周围白色脂肪细胞数量，显示：针灸增强了白色脂肪细胞的代谢，促进了白色脂肪细胞向棕色脂肪细胞的转化：肥胖大鼠PVN神经细胞自发放电频率增加，脑内单胺递质紊乱，针灸通过抑制PVN亢奋的自发放电，调整5-HT水平，达到影响食欲，改善代谢的作用；肥胖大鼠血中leptin及Ins水平增高，与正常组大鼠比有明显差异，提示大鼠体内存在leptin及Ins抵抗，针灸后肥胖大鼠随着体重体脂的下降，血中leptin、Ins水平降低，与肥胖组比均有显著性差异，而针灸后大鼠脑内leptin增加，与肥胖组比P.05，提示：针灸具有改善leptin、Ins抵抗及增加leptin脑内转运的作用。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。