脂蛋白

Objective To establish a new method for isolating serum β-lipoprotein subfraction s using second double gradient polyacrylamide gel electrophoresis.

目的建立一种分离血清β脂蛋白亚组分的新方法———二阶双梯度聚丙烯酰胺凝胶电泳法。

Enhanced susceptibility to in vitro oxidation of the low density lipoprotein subfraction in healthy subjects.Arteriosclerosis and Thrombosis,

认为低密度脂蛋白及亚组分氧化易感性的检测对了解LDL的氧化过程和防治心脑血管疾病有参考价值。

It showed that the cholesterol concentration of plasma high density lipoprotein fraction for hyperlipoproteinemia Ⅳ was lower than for normal group, especially for the cholesterol amount of HDL_2 subfraction (HDL_2-C).

结果表明，Ⅳ型患者血浆高密度脂蛋白分子内胆固醇含量远低于正常组，具有非常显著的差异(P.001)。特别是HDL_2亚组分中胆固醇含量(HDL_2-C)降低更为显著，与正常组比较有高度显著差异(P.901)，而HDL_3亚组分内胆固醇含量(HDL_3-C)，两组之间无统计学意义。

Feeding with rapeseed oil reduced the reacylation activity in both pathways, explaining the high accumulation of lipid droplets in the supranuclear portion of the intestinal epithelium, whereas soyabean oil enhanced phosphatidylcholine synthesis, being associated with the increase in VLDL found in previous studies.

虽然大豆油脂促进了卵磷脂的合成，以前的研究证实与超低密度脂蛋白的升高有关。

Hideyuki Doi, Nakui Madaki, Hrroshi, Hiromichi Komatsu, Keisei Fujimori and Susumu Satomi Tohoku. A New Preadipocyte Cell Line,AP-18,Established from Adult Mouse Adipose Tissue. J.Exp.Med,2005,207:209-216[2] Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor. Cell ,1994,79:1147－1156

PPARα调节脂肪代谢的机制总结如下：肝脏脂肪酸水平的增高激活PPARα，然后转录激活参与脂肪酸氧化的基因；配体与之结合后可激活编码乙酰辅酶A合成酶的基因，同时PPARα激活后可调节脂肪转运相关基因的表达如PPARα升高高密度脂蛋白和抑制ApoC－Ⅲ的表达。

PlasmaLDL was decreased markedly in cholesterol gallstone than in control group (p0.05). In cholesterol gallstone group, plasma TG and TG/TC ratio were significantly positive correlativity. Conclusions: These results indicate that the changes of plasma lipids may affect the metabolism of cholesterol and bile acids and itmay tade an important role in the formation of cholesterol gallstone. TG/TC ratio may act as an indirect reflect of reference index.

本实验结果提示：血浆脂蛋白的变化，可能因影响体内的胆固醇及胆汁酸等代谢而与胆囊胆固醇结石的形成密切相关，TC、TG的测定及TG/TC比值可以作为间接反映胆囊胆固醇结石成核的参考指标。

In the proband and at least 2 first-degree relatives, the low-density lipoprotein cholesterol should be above 4.921mM, with the presence of tendinous xanthomas.

病人本身及至少两个一等亲其低密度脂蛋白(low density lipoprotein， LDL)超过4.92mM，并/或在小时候即有肌腱黄色瘤。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1 (IGF-1) and the intervention effect of HMGcoA reductase inhibitor, atovastatin and immune supppressor, rapamycin.

目的：探讨氧化低密度脂蛋白，胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1(IGF-1) and the intervention effect of HMG-coA reductase inhibitor, atovastatin and immune supppressor .rapamycin.

目的：探讨氧化低密度脂蛋白，胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Laser confocal microscopy revealed the differentiating EPCs could uptake acetylated low density lipoprotein and ulex europaeus agglutinin-Ⅰ, which were stained as red and green fluorescence.

激光共聚焦显微镜鉴定乙酰化低密度脂蛋白、荆豆凝血素Ⅰ双染阳性的细胞为正在分化的血管内皮祖细胞。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。