脂蛋白

Methods Making use of the model of rabbits fed with high cholesterol diet and studing the regulating effects of ANBE from the three areas on lipoid content in serum.

结果 3产地 ANBE能明显降低高脂血症家兔血清总胆固醇、甘油三脂和低密度脂蛋白含量，显著升高高密度脂蛋白含量和 HDL- C/ TC比值，同时，能显著降低高脂血症家兔的过氧化脂质。

Present study aims to evaluate the effect of proso millet prolamin on cholesterol metabolism in mice, by comparing the concentration of plasma total cholesterol, high-density lipoprotein cholesterol with triglyceride of mice given the diets containing casein, soy protein isolated or PMP (supplemented with 1.82%Lys and 0.23%Trp).

比较了分别饲喂酪蛋白、大豆分离蛋白、黄米醇溶蛋白小鼠的血清总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇，甘油三酯浓度和动脉硬化指数，旨在评价黄米醇溶蛋白对小鼠胆固醇代谢的特定作用。

There were twelve different hepatocyte proteins interacting with HCBP12 by Yeast two-hybrid, containing human sapien apolipoprotein C-I/B, human sapiens mitochondrion, human sapiens metallothionein 2A, human sapiens beta-2-microglobin,human sapiens carboxylesterase, and human sapiens serpin peptidase inhibitor, with known function and one with unknown function.

利用酵母双杂交技术筛选出12个与HCBP12相互作用的蛋白，其中包括人类载脂蛋白C-I/B、人类线粒体蛋白、人类金属硫蛋白2A、人类β-2微球蛋白、人类羧酸脂酶4和人类丝氨酸肽酶抑制剂等已知功能蛋白及1个未知功能蛋白。

The apolipoproteins on the surface of the lipoproteins help to solubilize the lipids and target the lipoproteins to the correct tissues .

在脂蛋白表面的载脂蛋白有助于溶解脂质，并把脂蛋白导向适当的靶组织。

The program of AER+RES was similar to AER, but went through resistance exercise 20min in base section of every exercise trail.Result: Prior to intervention, adiponectin levels were significantly correlated with BMI、 WHR、 COS、 LN、 LN、 TG、 LG10、 LN、 weight、 waist、 FM、%F, and leptin levels were significantly correlated with BMI、 WHR 、 LN 、 LN 、 TG 、 HDL-C 、 LG10、 apoB 、 apoA1/apoB、 waist、 F1M、%F. Stepwise multiple regression analysis revealed that LG10; COS and waist was an predictor of basal adiponectin levels , and %F,apoB and WHR was an predictor of basal leptin levels. In early obesity, adiponectin and leptin can be worsened , along with the changed of body component, fasting plasm glucose and lipid accumulation. After intervention, both group were significantly reduction in FM,%F,weight, WHR,FPG and TG, while HDL-C had significantly increased.AER exhibited significant in leptin, while AER+RES did not show the change. Insulin and HOMA-IR were changed in both groups. The control group exhibited no significant change in any variables. Although adiponectin levels were unchanged in the three groups, a significant negativecorrelation between delta %F, delta WHR and delta FPG was observed. Futhermore, if compare the degree of delta weight, we fought a significant increased in adiponectin between the group of delta weight higher (=3kg) than delta weight lower(=0kg), delta %F, delta WHR and delta weight were significant negative correlation with delta leptin.

结果：绝经妇女脂联素水平与体重指数、腰臀比、空腹血糖、空腹胰岛素、LEP、TG、极低密度脂蛋白胆固醇、胰岛素抵抗指数、体重、腰围、体脂含量、体脂百分比显著相关；瘦素水平与BMI、WHR、FINS、LEP、TG、HDL-C、VLDL-C、载脂蛋白B、apoA1／apoB、腰围、FM、％F等指标显著相关；多元逐步回归分析显示LG10、COS和腰围是基线脂联素水平的预测变量，而％F，apoB和WHR是基线瘦素水平的预测变量；在肥胖前期，脂联素、瘦素已经出现明显不良变化，同时也伴随着体成分、空腹血糖和血脂的异常；运动实验后，两个运动组的FM、％F、体重、WHR、FPG、TG都显著下降，而HDL-C显著上升；AER组瘦素显著下降，而AER+RES组则没有显著变化；两组的胰岛素和HOMA-IR水平都有显著下降；对照组所有指标都没有明显变化；尽管运动后脂联素水平没有显著变化，但是脂联素变化量与％F、WHR和血糖变化量显著负相关，而且如果按照运动后体重下降的程度比较，则体重下降大(≥3kg)的受试者比下降小的(≤0kg)脂联素水平有明显升高；运动后瘦素水平的变化量与％F，WHR及体重的变化量显著负相关。

Compared with Simvastatin Tablets and the capsule of Xuezhikang,the effects of Wendan decoction on serum triglycerides,serum total cholesterol,serum LDL-C and serum HDL-C in adult rats with chronic hyperlipidemwere observed after30dates.Result:By using pharmacological meth-od,the results revealed that Wendan decoction could effectively reduce serum of TC,TG,LDL-C levels in the rats with chronic hyperlidemia,it has raisen the concents of blood HDL-C and its function was more effective than the capsule of Xu-ezhikang.

除空白对照组喂基础饲料外，其余各组均采用高脂乳剂灌饲方式建立大鼠高脂血症模型，喂养10日后眼球取血，测得受试动物血清中总胆固醇、总甘油三酯、低密度脂蛋白胆固醇显著升高，说明高脂血症模型复制成功。30日后，运用药理学方法，观察温胆汤对高脂血症成年大鼠血清中TC、TG、LDL-C、高密度脂蛋白胆固醇含量的影响，并与西药辛伐他汀、中成药血脂康进行比较。

Compared with these of fat-fed group, the body weight, blood glucose levels after oral glucose and the glucose area under curve, 40min and 90min blood glucose levels after insulin injection subcutaneously and the glucose area under curve in the insulin tolerance test, the fasting serum insulin, insulin resistance index, serum cholesterol, triglyceride and lower density lipoprotein cholesterol decreased, the fasting serum leptin, high density lipoprotein cholesterol and C18:2 were significantly increased in N-6 PUFAs group.

n-6脂肪酸组从第1~10周体重均较高脂组明显减轻，糖负荷后血糖和糖耐量试验中葡萄糖曲线下面积、皮下注射胰岛素后40min、90min血糖及胰岛素耐量试验中葡萄糖曲线下面积、血清胰岛素、胰岛素抵抗指数、血清胆固醇、甘油三酯和低密度脂蛋白含量均较高脂组明显降低；血清瘦素水平、高密度脂蛋白、18碳2烯酸较高脂组明显升高。

Methods: The hospitalized cases with EH and HS were collected in a 3-A grade hospital of Xi'an city (from Jun. 2001 to Mar. 2005) according to the includible standard and excludible standard. Unified questionnaires were filled in. The items of questionnaires included: sex, age, inhospital days, death in hospital, first-measured blood pressure Systolic blood pressure (SBP, Diastolic blood pressure, Pulse pressure, blood lipid total cholesterol (TC, Triglyceride, High density lipoprotein cholesterol, Low density lipoprotein cholesterol, Apolipoprotein A and B.

检索西安市某三级甲等医院2001年6月－2005年3月期间EH合并HS住院病例，按照纳入标准和排除标准筛选病例资料，填写统一调查表，调查项目包括：性别、年龄、住院天数、死亡情况、首测血压、血脂（总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、载脂蛋白A以及载脂蛋白B）等指标，并按性别与年龄分层进行回顾性分析和研究。

Conclusions-This is the first study to demonstrate that intestinal TRL apoB-48 production is increased after short-term elevation of plasma FFAs in humans in the fed state, similar to the well-described stimulation of hepatic TRL apoB100-containing particles by FFAs.

结论-这项研究首次表明人类在进食状态下血浆游离脂肪酸短期升高会促进肠内载脂蛋白B-48甘油三酯脂蛋白的合成，与多项研究证实的游离脂肪酸可促进肝脏载脂蛋白B-100甘油三酯脂蛋白的合成相似。

" As a result,"the primary focus should be on LDL, said review co-author Mehdi Shishehbor, D.O., of the Cleveland Clinic.

作者的结论是，尽管努力降低低密度脂蛋白(低密度脂蛋白或&坏胆固醇&)&不断降低心血管疾病风险，高密度脂蛋白的做法要复杂得多，有时令人失望&作为一个结果，&应该把主要焦点对低密度脂蛋白，说：&检讨合著梅迪shishehbor ， d.o。，克利夫兰诊所。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。