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脂肪酶

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Thyroid hormone responsive spot 14, expressed in lipogenic tissues, is suggested as a transcription factor to regulate gene expression of rate-limiting enzymes in lipogenesis. Two THRSP isoforms, THRSPα and THRSP β, were detected at cDNA levels in chickens and ducks.

甲状腺激素应答Spot 14 (Thyroid hormone responsive spot14, THRSP)是一个参与多种脂肪合成限速酶基因表达的转录调控因子,在动物肝脏、乳腺和脂肪组织中高度表达。

The conclusion indicated that pyruvate supplement could accelerate the speed of body energy metabolism and slower weight and body fat gain during exercises. Due to the influences of pyruvate supplement on the levels of enemies and hormones to adjust body lipometabolism during exercises, body blood lipid and glucose levels decreased, and the process of fat metabolism came under.

丙酮酸补充可在一定程度上减慢运动机体体重和体脂的增长速度,加快运动机体能量代谢速度;并通过影响运动机体脂肪代谢相关调控酶和激素水平,使其血脂和血糖水平下降,从而影响其脂肪代谢过程。

The expression of FAS was enhanced sighificantly in the livers of the NAFLD patients. Conclusion Enhanced expression of SREBP-1 c and FAS maybe a factor causing hepatic lipopexia in NAFLD patients.

结论肝细胞SREBP-1c表达增加,导致脂肪酸合成酶蛋白增加,脂肪合成增加是NAFLD患者肝脂肪蓄积的原因之一。

Methods: Seven male patients with kidney stones were admitted. Abdominal subcutaneous adipose tissue and perirenal adipose tissue were collected from the operating-patients, and were cultivated with different concentrations of curcumin (10 and 100 μg/ml) in vitro.

用体外组织培养法培养手术后离体人脂肪组织,分别予10和100μg/ml姜黄素干预6h和24h,用夹心酶联免疫吸附测定法检测各脂肪组织培养液中APN和IL-6的含量。

The results showed:the fatty acid composi- tion of crude fish oil and refined fish oil of Rachycentron canadum Linnaeus muscle have not the obvious change,mainly the 18 kinds of fatty acids of C_(14)~C_(22);the content of unsaturated fatty acid was 44.31% and 48.53% respectively;the total content of eicosapentaenoic acid and doconsahexaenoic acid...

结果表明:军曹鱼鱼肉粗鱼油和精制鱼油脂肪酸组成没有明显变化,主要由C14~C22的18种脂肪酸组成,不饱和脂肪酸含量分别为44.31%、48.53%;二十碳五稀酸和二十二碳六稀酸总量分别为13.67%、14.88%;酶解蛋白粉粗蛋白含量为95.77%,脂肪含量0.32%,灰分5.45%,具有高蛋白、低脂肪、矿物元素丰富的特点;必需氨基酸占氨基酸总量的41.58%,必需氨基酸之间比例适宜,符合FAO/WHO推荐的理想蛋白质模式。

The results showed as:(1)Gegen decreases fasting insulin and insulin resistance index and increases insulin sensitive index of rats of insulin resistance induced by dexamethasone significantly;(2)Gegen can improve glucose tolerance of rats of insulin resistance but not to alloxan indued diabetes mice;(3)Gegen increases glucose intake of 3T3-L1 adipocytes and improves the insulin resistance of 3T3-L1 adipocytes induced by dexamethasone significantly;(4)Gegen can activate peroxisome proliferator- activated receptor gamma, make it bind to PPAR response elements;(5)Gegen can up-regulate mRNA expression of PPAR v ,aP2 and adiponectin.

结果表明:①葛根显著降低地塞米松诱导的胰岛素抵抗大鼠血清胰岛素水平和胰岛素抵抗指数,升高胰岛素敏感指数,改善大鼠的胰岛素抵抗;②葛根显著改善胰岛素抵抗大鼠的糖耐量,但对四氧嘧啶糖尿病小鼠的糖耐量没有明显的作用;③葛根显著增加胰岛素抵抗3T3-L1脂肪细胞对葡萄糖的摄取,改善地塞米松诱导的3T3-L1脂肪细胞的胰岛素抵抗;④葛根能促进HepG2肝癌细胞过氧化物酶体增殖物激活受体γ与靶基因的特异DNA序列结合,对PPARγ及其下游基因的转录具有激活作用;⑤葛根能够促进PPARγ及其下游基因脂肪酸结合蛋白(aP2)、脂联素mRNA的表达。

METHODS: All rats in each groups were narcotized and executed after continuous feeding 1 week, biochemical analysis and enzyme assay were made respectively after blood samples were adopted, and liver, subcutaneous fat, mesentery fat tissue and gastrocnemius muscle were preserved.

各组大鼠连续喂饲1周后,麻醉处死大鼠,采取血样,留取肝脏、皮下脂肪、肠系膜脂肪组织以及腓肠肌,分别进行生化分析和酶活性的测定。

Also with light tea alternate feed. 4, if necessary, go to the hospital drips, add water, electrolytes and glucose, to prevent dehydration and acidosis. 5, breast milk contains more lactose, most lactose enzyme decomposition of absorption and less by the Department at the end of fermentation to digest the lactose, producing gas, acid production, stimulate the intestinal tract, so that stool was diarrhea-like discharge. 6, breast and milk contain fat, part of being broken down into fatty acids and glycerol absorption, not alkaline digestion of fat in small granular form of calcium soap, so that stool can not appear in the first one to digest things.

还可与淡茶水交替喂。4、必要时去医院打点滴,补充水分,电解质和葡萄糖,以防脱水和酸中毒。5、母乳中含乳糖较多,大部分被乳糖分解酶分解吸收,少部末被消化的乳糖发酵、产气、产酸、刺激肠道,使大便呈腹泻状排出。6、母乳和牛乳均含有脂肪,一部分被分解为脂肪酸和甘油吸收,未被消化的脂肪碱性的钙形成小颗粒状的肥皂,使大便中出现消化不掉的一颗一颗的东西。

Sativa meal and both weight gain rate and relative growth rate also increased significantly. The above indexes of fish fed 4% and 12% M. sativa meal were higher than those of fish fed 16% M. sativa meal and were lower for fish fed fresh M. sativa than that of the control group. 2 With increased levels of M. sativa meal in the diets, crude protein content in the muscle of fish fed M. sativa meal increased significantly, while EE and cholesterol were significantly decreased and moisture showed a quadric curve variation. Fish fed fresh M. sativa had no improvement in comparison to the control group. 3 Protease and amylase in foregut, midgut, hindgut and hepatopancreas of C. carpio increased with increased M. sativa meal but the variation was not linear.

试验Ⅰ、Ⅲ组的上述2项指标高于对照组,试验Ⅳ组低于对照组,苜蓿鲜草组低于对照组,但差异均不显著。2和对照组相比,添加苜蓿草粉显著或极显著提高了禾花鲤肌肉中粗蛋白质含量,随着苜蓿草粉添加水平的增加,肌肉中粗脂肪和胆固醇水平显著下降,肌肉中水分含量呈先降后升的二次变化趋势,苜蓿鲜草组的肌肉中粗蛋白质、粗脂肪含量和胆固醇水平无显著变化。3添加苜蓿草粉后对消化道各部位蛋白酶活性及淀粉酶活性有促进作用,均呈先升后降的变化趋势,其中试验Ⅱ组的酶活性最高。

FOXC2 affects adipocyte metabolism by increasing the sensitivity of the β-adrenergic-cAMP-protein kinase A signaling pathway through alteration of adipocyte PKA holoenzyme composition.

FOXC2通过对各种参与代谢重要基因的调控和提高β-肾上腺素能-cAMP-蛋白激酶A信号通路的敏感性,改变脂肪细胞PKA全酶的组成来影响脂肪细胞的代谢。

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