脂肪代谢

In 2007 European Association for the Study of Diabetes, it is announced that DDP Ⅳ inhibitor can impact anabolism of fatty tissue through adjusting the antilipotropism of NPY in the fatty tissue. What do you think about this problem?

在2007EASD会议上就公布了一项关于DPP IV抑制剂通过调节脂肪组织中的NPY抗亲脂作用而影响脂肪组织代谢的研究结果，您对这个问题怎么看呢？

Objective To assess the impact of liver fat content on beta cell function andinsulin sensitivity in patients with NAFLD.

目的分析非酒精性脂肪肝病肝脏脂肪变程度与糖脂代谢的关系，探讨NAFLD与胰岛素抵抗的关系。

In an effort to develop a simple method for identifying patients who may have fatty liver disease, Dr. Bedogni and colleagues used data from the Dionysos Nutrition and Liver Study to determine the degree to which drinking habits, anthropometry, and metabolic parameters contribute to the risk for the condition in 216 patients with suspected liver disease but no hepatitis B and C infection as well as in 280 age- and sex-matched controls. All participants were from the same town in northern Italy. The presence of fatty liver disease was confirmed via ultrasonography. Results were presented here by Vittorio di Maso, MD, another researcher at the Liver Research Center, at the 41st annual meeting of the European Association for the Study of the Liver.

为了发展出一个简单的方法於鉴定脂肪肝疾病病患，Bedogni 医师及其同僚使用迪奥尼修斯营养与肝脏研究的数据，对280位年龄与性别相符者之中的216位疑似有肝脏疾病但无B型或C型肝炎的病患，加以区别饮酒习惯、人体测量学、导致风险的代谢参数等，所有参与实验者都是来自义大利北部的一个城镇，藉由超音波扫瞄确定出现脂肪肝疾病；研究结果在欧洲肝脏研究学会第41届年会由前述肝脏研究中心的另一位研究员、Vittorio di Maso 医师发表。

Phosphatide play an important role in the transportation of fat. Phosphatide can participate in fatty acid metabolism, and helps crude fat dissolve and absorb.

磷脂对脂肪的转运起着重要的作用，其参与脂肪酸代谢，帮助脂肪溶解与吸收。

Phosphatide function which emphatically wants to the fat transportation, its participation fatty acid metabolism, helps Crude fat dissolves and the absorption.

磷脂对脂肪的转运起着重要的作用，其参与脂肪酸代谢，帮助脂肪溶解与吸收。

Aim To understand the features of lipoprotein lipase and its role in the distinctive lipid metabolism in tree shrew, which is considered to be an animal protected from atherosclerosis.

目的 了解不易感动脉粥样硬化动物树鼩的脂蛋白脂肪酶的结构和活性特点，并与其它种属比较，探讨脂蛋白脂肪酶在树鼩独特脂代谢中的作用。

The experiment two: enzyme preparation significantly improved average daily gainand feed conversion ratio (P＜0.05). Enzyme preparation significantly increased energymetabolizability and digestibility of crude fiber, crude protein and neutral detergent fiber,but had no remarkable effect on digestibility of dry matter, crude fat and acid detergentfiber. Enzyme preparation significantly decreased the relative viscosity of duodenal andjejunal digesta. The pH of intestine had no noticed difference in all groups. Enzymepreparation significantly decreased relative weight of gizzard, proventficulus, duodenum,jejunum and ileum. Enzyme preparation significantly increased villus size of duodenumand jejunum, and villus to crypt ratio of duodenum and ileum significantly increased too.Enzyme preparation considerably decreased ileal crypt height (P＜0.05), and didn"t affectthickness of intestinal wall. Supplementing enzyme preparation, the serum glucose, totalprotein and alanine aminotransferase, but enzyme preparation hadn"t noticed influenceupon uric acid, total cholesterol, triglyceride and high-density lipoproteins. Enzymepreparation significantly increased insulin, triiodothyronine and insulin-like growthfactor-Ⅰ. Adding enzyme preparation, the percentage of thyroid stimulating hormone andgrowth hormone in the serum increased 16.44%, 19.18% and 18.84%, 21.74%respectively, and the percentage of glucagon and thyroxine decreased 12.07%, 14.36% and 13.79%, 15.40%, but failed to reach statistical significance (P＞0.05). Enzymepreparation significantly increased (P＜0.05) the trypsin and amylase activity of duodenaland jejunal digesta, but enzyme preparation didnt affect significantly (P＞0.05) theintestinal lipase activity and pancreatic digestive enzyme. Enzyme preparation had nosignificant effect on caecal microbial population.

试验二：酶制剂显著提高平均日增重和饲料转化率(P＜0.05)；酶制剂显著提高能量代谢率及粗纤维、粗蛋白、中性洗涤纤维消化率(P＜0.05)，而对干物质、粗脂肪、酸性洗涤纤维消化率影响不显著；酶制剂显著降低十二指肠和空肠食糜相对粘度(P＜0.05)；添加酶制剂对肠道pH影响不显著；酶制剂显著降低肌胃、腺胃、十二指肠、空肠、回肠相对重(P＜0.05)，显著提高十二指肠和空肠绒毛高度，显著增加十二指肠和回肠绒毛高度／隐窝深度，降低回肠隐窝深度(P＜0.05)，对肠壁厚度影响不显著；酶制剂显著提高血清葡萄糖、总蛋白和谷丙转氨酶浓度(P＜0.05)，对尿酸、总胆固醇、甘油三酯及高密度脂蛋白浓度影响不显著，显著提高胰岛素、T_3、IGF-Ⅰ水平，添加酶制剂后，促甲状腺激素、生长激素分别提高16.44％、19.18％和18.84％、21.74％，胰高血糖素和T_4分别降低12.07％、14.36％和13.79％、15.40％，但差异不显著；酶制剂对胰腺消化酶活性影响不显著，显著增加十二指肠和空肠胰蛋白酶、淀粉酶活性，对小肠脂肪酶活性影响不显著；酶制剂对盲肠微生物菌落数影响不显著。

Objective To investigate the direct effect of high-level leptin on lipolysis and lipopexia of human adipocyte, and to explore the autocrine regulation of adipocyte.

目的：观察高浓度瘦素对人脂肪细胞分解代谢及脂肪蓄积的直接影响，探讨瘦素自分泌调节在肥胖发生中的作用。

There was no difference of FSHR expression in subcutaneous and omental adipose tissue from premenopausal, perimenopausal and postmenopausal men and women.

我们的研究首次阐述了脂肪组织上FSHR的表达和功能，第一次提出FSH直接调控脂肪分化、代谢的观点，FSH-FSHR信号调控开创了绝经期肥胖症研究的崭新方向，开拓了垂体糖蛋白受体新的研究领域。

The roselle calyx can promote the Abs of the fat in Jimpy mice.

苏丹红能促进小鼠体内脂肪的吸收，但对小鼠体内脂肪的代谢呈现剂量相关的双向性。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。