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PPARs have diverse biological functions such as enhancing insulin sensitivity, regulating saccharometabolism homeostasis, and especially regulation of lipid homeostasis, which is the focus of much of the researches at present. In this article, we summarize the regulation of fat metabolism by PPAR genes based on their structure, function and expression.

PPARs具有多种生物学功能,如增强机体对胰岛素敏感性,调节体内糖平衡等,尤其在脂肪分化、生成等多方面起到重要作用,是目前的研究热点,文章从PPARs基因的结构,表达及功能等方面讨论了其与脂肪代谢调控的关系。

A minority of retroperitoneal liposarcomas may, either at the time of initial diagnosis or at the time of local recurrence, contain nodule of non-lipogenic sarcomatous elements.

少数腹膜后脂肪肉瘤可以在初次诊断或局部复发时发现局灶区非脂肪肉瘤的肉瘤成分。

Korea Shab produce with human itself the same frequency far infrared, a body of water elements resonance for water elements fierce campaign superfluous fat, heavy metals trapped in the water elements, enabling water elements enable hazardous substances and fats released and discharged in vitro, because Korea homes is "dry cleaning" in Korea homes inside to listen to music, drink coffee, read :: without that kind of steamed into massage room temperature dejected.

丽舍能产生与人体本身相同频率的远红外线,引起体内水分子共振,使水分子剧烈运动,多余的脂肪、重金属被夹在水分子之间,激活的水分子能够使有害物质和脂肪被释放并排出体外,由于丽舍是&干洗&,在丽舍里面,可以听音乐、喝咖啡、看书……而没有桑拿房那种蒸笼似的高温憋闷。

The adipose derived stem cells of inbreds train of rat wereinduced to differentiate into schwann-like cells and the cells were injectedinto the acellular nerve allograff.The proliferation or adhersion of these cells on the graft were observed by inverted microscope or ScanningElectronic Microscope. Activity of cells were detected using MTT. 10mmnerve gap of inbreds train of rats in two group were bridged by tissue-engineered peripheral nerve or autogenous nerve, the effect wereappraised by naked eye, recovery rate of sciatic function index,nerve-electrophysiological, histology, Transmission ElectronMicroscopy and quantitative analysis of recovery rate of myelinated fiberpopulations,diameter of myelinated fiber and thickness of myelin sheat.

按照前述方法培养并诱导近交系大鼠脂肪干细胞向类Sehwann分化,将诱导分化的脂肪干细胞悬液注入已制备的去细胞同种异体神经支架管中,倒置显微镜观察细胞生长情况;扫描电镜下观察细胞在材料上附着情况;四唑盐比色试验测定细胞活性;取两组近交系大鼠,分别用组织工程化神经和自体神经桥接10mm神经缺损,通过大体观察、坐骨神经功能指数恢复率的测定、神经电生理的测定、组织学光镜观察、透射电镜观察、再生有髓神经纤维计数恢复率、神经纤维直径恢复率、髓鞘厚度恢复率的测定等指标评价实验效果。

Thirty-seven of 38 patients with follow-up are alive without disease and 1 is alive with disease (median 59 mo follow-up duration, range: 8 to 108 mo). Six cases showed myxoid liposarcoma with spindled growth (spindle cell myxoid liposarcoma); these arose in 5 females and 1 male (median age 14 y) and involved the thigh in 40% of cases.

随访的38例都存活,其中37例无再发,1例伴病(随访中位时间为59个月,范围:8至108个月)。6例黏液样脂肪肉瘤的瘤细胞生长方式为梭形(梭形细胞黏液样脂肪肉瘤),患者为5名女性、1名男性(中位年龄14岁),40%病例的肿瘤发生于大腿。

Department of shark liver oil from non-toxic animals such as fish liver Squalidae raised in a fatty oil, about taking off at 0 ℃ after some solid fat, and refined edible vegetable oils, cod liver oil or a high concentration of vitamin A and vitamin D3 regulation of the concentration of coupled with the appropriate amount of stabilizer made.

鱼油就是鱼甘油吗?鱼肝油系自鲛类动物Squalidae 等无毒海鱼肝脏中提出的一种脂肪油,在 0℃左右脱去部分固体脂肪后,用精炼食用植物油、浓度较高的鱼肝油或维生素A与维生素D3调节浓度,再加适量的稳定剂制成。

Effect: The unnecessary steatolysis metabolism will leave in vitro, will achieve perfect curve, models effect valley thin abdomen.

功效:透过身体解剖,从器官,神经,血管,脂肪层等的运作,将囤积脂肪层分解代谢出体外,进而达到完善曲线纤腰瘦腹之效果。

Effect: The thorough subcutaneous tissue four centimeters, the decomposition fat, removes the unnecessary toxin, the sculpture stature, exactly follows the meter using the filament body, strengthens the steatolysis and the consumption.

功效:刺激相关经络,疏通神经关节,直接深入皮下组织四公分,分解脂肪,排除多余毒素,兼具雕塑身材之双重效果,利用纤体活循仪,针对肥胖部位雕塑减脂,配合纤体产品,加强脂肪分解与消耗,提升身体基础代谢率。

The RNAi technology can effectively inhibit the expression of lipoxygenase gene in soybean seed, decrease the activity of lipoxygenase, increase the amount of oil content in its products, improve the quality of soybeans, and create new superordinary germplasm resources of soybean.

应用RNA干扰技术可有效的抑制大豆籽粒中脂肪氧化酶基因表达,降低脂肪氧化酶活性,提高大豆油份含量,改良大豆品质,创造优良大豆种质。

Hideyuki Doi, Nakui Madaki, Hrroshi, Hiromichi Komatsu, Keisei Fujimori and Susumu Satomi Tohoku. A New Preadipocyte Cell Line,AP-18,Established from Adult Mouse Adipose Tissue. J.Exp.Med,2005,207:209-216[2] Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor. Cell ,1994,79:1147-1156

PPARα调节脂肪代谢的机制总结如下:肝脏脂肪酸水平的增高激活PPARα,然后转录激活参与脂肪酸氧化的基因;配体与之结合后可激活编码乙酰辅酶A合成酶的基因,同时PPARα激活后可调节脂肪转运相关基因的表达如PPARα升高高密度脂蛋白和抑制ApoC-Ⅲ的表达。

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