脂瘤

Methods:35 cases of otic neoplasms confirmed by clinic and biopsy, including 16 cases of acoustic neuroma, 3 cases of facial nerve neuroma, 10 cases of glomus jugulare tumor, 3 cases of carcinoma of middle ear, 3 cases of congenital cholesteatoma.

35例经临床病理证实的耳部肿瘤，其中听神经瘤 16例，面神经瘤 3例，颈静脉球瘤 10例，中耳癌 3例，先天性胆脂瘤 3例，全部病例均行CT检查，根据需要部分病例行MRI检查。

Methods:35 cases of otic neoplasms confirmed by clinic and biopsy, including 16 cases of acoustic neuroma, 3 cases of facial nerve neuroma, 10 cases of glomus jugulare tumor, 3 cases of carcinoma of middle ear, 3 cases of congenital cholesteatoma. All cases had CT examination and some of them had MRI examination when needed.

35例经临床病理证实的耳部肿瘤，其中听神经瘤16例，面神经瘤3例，颈静脉球瘤10例，中耳癌3例，先天性胆脂瘤3例，全部病例均行CT检查，根据需要部分病例行MRI检查。

Results Among these cases,the main CT features of the tympanic cholesteatoma included:soft tissue density tumor shadows in the tympanic sinus and cavity;bone destruction;sclerosis of the bone borders of tympanic sinus and cavity;destruction and shifting of the auditory ossicle chain.

结果 该组病例中，胆脂瘤性中耳炎的CT主要表现有：中耳窦腔内软组织密度瘤影；骨质破坏；中耳窦腔骨缘硬化；听小骨链破坏、移位。

Result 1. CDK4, P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium. Their positive rates were 68.6% and 88.6% respectively. Statistical analysis showed that there was a significant difference in positive rates between

CDK4与P16在中耳胆脂瘤上皮中均过度表达且有一定程度的正相关性，表明它们在疾病发生中是共同而非单独起作用的，从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖，使凋亡同时加快而达到新的平

Result: CDK4 and P16 were expressed in parabasal layers and the upper layer, mainly in the prickle and granular layers of cholesteatoma epithelium.

CDK4与P16在中耳胆脂瘤发生中是共同而非单独起作用的，从细胞周期的角度可反映胆脂瘤上皮细胞过度增殖的同时也增强负调控因子来抑制增殖，使凋亡同时加快而达到新的平衡。

It was postulated that the obstruction of pneumatized temporal bone air cells,caused by other middle ear diseases such as cholesteatoma and tympanosclerosis,might be the pathophsiological mechanism of CG.

胆固醇肉芽肿的发病机制为中耳的其它疾病如胆脂瘤、硬化灶等导致的通气受阻，仅凭CT及临床体征不能区别胆固醇肉芽肿与胆脂瘤，MRI对本病诊断有极大的价值。

DNA content within 25 cholesteatoma tissues and 10 normal postauricular skin was measured with flow cytometry.

利用机械捣碎法将新鲜的胆脂瘤和外耳道上皮制成单细胞悬液；采用PI法，对25例胆脂瘤上皮和10例正常外耳道细胞上皮的DNA进行流式细胞术分析。

Objective:To observe the morphology of eroded auditory ossicles obtained in middle ear surgery for cholesteatoma and to investigate the mechanism of bone erosion in cholesteatoma.

目的：观察胆脂瘤破坏听小骨的形态学结构变化，探讨胆脂瘤的骨质破坏机制。

Middle ear cholesteatoma is destructive to auditory ossicles and temporal bone, and treatment usually requires surgical removal of all epithelial content.

中耳胆脂瘤在临床上对於中耳裂具有相当的破坏性，而治疗上通常必须藉手术清除中耳腔所有的胆脂瘤上皮成分。

Methods: Thirtyfive cholesteatomas tissues and twenty normal human external ear canal skin were used in this study.

采用免疫组织化学技术SABC法检测CDK4、P16在中耳胆脂瘤35例、正常外耳道皮肤20例中的表达，并结合胆脂瘤对听小骨骨质破坏程度，采用SPSS11.5软件进行统计学分析。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新