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Glucocerebrosidase, the enzyme defective in Gaucher disease, is targeted to the lysosome independently of the mannose-6-phosphate receptor.

葡糖脑苷脂酶在高雪病患者中表现为缺陷型,它靶向性结合不依赖于甘露糖-6-磷酸的溶酶体。

Metabolic cherry-red spot occurs in other lysosomal enzyme deficiences such as generalized gangliosidosis (GM 1), Sandhoff's, Gaucher's, mucolipidosis Types 1 and 2, Niemann-Pick Type A, and multiple sulfatase deficiency. Vision is usually subnormal because the ganglion cells are not working properly.

代谢性眼部樱桃红斑发生在许多溶酶体酶缺乏的疾病中出现,如GM1神经节苷脂贮积病,sandhoff病,高雪氏病,粘脂质贮积病1,2型,尼曼匹克病A型,及多种硫酸酯酶缺乏病等,由于神经节细胞异常,视力一般轻度受损。

The repeatability and reproducibility of microwave testing chemical composition of ramie were studied. Five microwave ovens were applied in this experiment to test ceride, hydrotrope, pectin and hemicellulose in raw ramie samples .

摘要研究了苎麻化学成分微波检测法的重复性和再现性,试验采用苎麻原麻样品在5台不同的微波炉上提取测定脂蜡、水溶物、果胶及半纤维素。

The repeatability and reproducibility of microwave testing chemical composition of ramie were studied. Five microwave ovens were applied in this experiment to test ceride, hydrotrope, pectin and hemicellulose in raw ramie samples .

研究了苎麻化学成分微波检测法的重复性和再现性,实验采用苎麻原麻样品在5台不同的微波炉上提取测定脂蜡、水溶物、果胶及半纤维素。

"Since insolubility is the defining characteristic, cholesterol and related steroids, carotenoids, prostaglandins, and various other compounds are also classifiable as lipid s."

由于不溶性是决定性的特点,所以把胆固醇以及与之相关的类固醇、类胡萝卜素、前列腺素以及各种各样其它的化合物也归类于类脂化合物。

Six experimental stages were designed in our procedure, those are:(1) metabolite recovery and tested sample preparation: the metabolites were recovered by Amberlite XAD-2 absorption, followed by MeOH elution and solvent concentration;(2) antioxidant detection and strain selection: samples were quantitatively analyzed by the inhibition effects on formation of lipid peroxides and TBARS to screen the strains able to produce antioxidants. According to the established screening methods, we chose out a strain of actinomycetes, designed as AMBL-029C;(3) antioxidant purification: the fermentation broth was recovered by a series of separation techniques including centrifugation, Amberlite XAD-2 absorption, followed by MeOH elution and a successive TLC purification. The resulting primary purified compound [temperately designed as AMBL-029C-TS] was further analyzed by HPLC to monitor its purity;(4) physical-chemical characteristics: judging from the acid-base fractionation experiments, and the pH and temperature stability tests, the compound was deduced to be a acidic compound with the properties of low polarity and highly pH and temperature stable;(5) mechanism of the antioxidant: in comparison with some other known antioxidants, TS was subjected to investigate its antioxidant mechanism, together with BHT,-tocopherol, as well as two streptomyces metabolites, homogentisic acid and -phenylpyruvic acid, which were previously isolated as the natural antioxidants in our laboratory.

针对本实验目的,我们设计了以下的实验步骤﹔(1)二次代谢物回收及检测样本处理:我们将发酵所得的培养上清液,利用疏水吸附性树酯Amberlite XAD-2吸附回收,并以甲醇溶离及真空减压浓缩脱水等方式处理,以取得提供抗氧化活性筛选之检测样本;(2)抗氧化活性检测及菌种筛选:以「过氧化脂质」和「硫丙二醯尿」的生成量进行定性定量分析以作为抗氧化物质生产菌筛选之用;经此筛选程序,我们选获了具有抗氧化物质高生产力的菌株,命名为AMBL-029C;(3)抗氧化物质的分离纯化:针对生产菌株的发酵回收处理液,以矽胶薄层色层分离法经物质层析纯化后,并以高效能液相层析法(High performance liquid chromatography;HPLC)分析物质可得一初级纯化物质,命名为AMBL-029C-TS;(4)抗氧化物质的物理化学性质分析:由酸碱转溶(acid-base fractionation)实验得知,此抗氧化物质属於中低极性的强酸性物质,对温度(37℃-100℃)及酸碱度(pH3.0-13.0)均表现出高稳定性;(5)在抗氧化机制探讨方面,我们针对数种不同的抗氧化机制进行探讨,即: 1。

The main target of PDT-CPD4 was probably membrance organelles, such as cytomembrance、lysosome、microsome. It made lipide and protein of these membrance dissociate and degenerate, membrance penetration increased. Typical biochemical changes appeared, 180bp bases DNA fragmentation ladder pattern was observed in agar electrophoresis.

但PDT作用后出现线粒体肿胀,可能是因为PDT的主要靶部位是膜性细胞器如线粒体、胞质膜、内质网和溶酶体等,光化学反应产物使这些膜的脂类和蛋白质发生分解变性,膜通透性增高所致。

Among surface-active lipoidal substances, lysolecithin is probably the best studied with regard to its fusing capabilities

具有表面活性的脂类物质中,溶血卵磷脂就其融合性来说可能是研究得最为彻底的。

The copolymer of N isopropylacrylamide and acrylamido azobenzene was synthesized for the study of the effect of the photoisomerization of a water soluble copolymer containing azobenzene groups on the photocontrolled release behavior of liposomes.

为了研究侧链含有偶氮苯基的水溶性共聚物的光异构化对脂质体内包容物的光控释放的影响,设计合成了N-异丙基丙烯酰胺和丙烯酰胺基偶氮苯的共聚物。

Nicotinic acid, which is also called niacin, is a water soluble vitamin B. It improves levels of all lipoproteins when the doses are given far above the vitamin requirement.

烟酸,也被称为烟碱酸,是一种水溶性维生素B ,提高水平的所有脂蛋白的剂量时,给出了远远高于维生素的要求。

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The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为:以确有疗效的中药复方为研究对象,以现代科学技术和传统中医药理论为技术支持,以该复方所治病证的药效响应为评价标准,以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。

I don't… don't know. He's unconscious.

我不……我不知道他休克了。