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Methods Making use of the model of rabbits fed with high cholesterol diet and studing the regulating effects of ANBE from the three areas on lipoid content in serum.

结果 3产地 ANBE能明显降低高脂血症家兔血清总胆固醇、甘油三脂和低密度脂蛋白含量，显著升高高密度脂蛋白含量和 HDL- C/ TC比值，同时，能显著降低高脂血症家兔的过氧化脂质。

Both the increase of lipid peroxidation reaction rate and the shortening of the latent period were dependent on the pre-existed lipid peroxides in liposomes. Al3+ accelerated the oxidation of Fe2+ in liposomal system only when liposomes contain pre-exist peroxides. The addition of Al3+ to the liposomal suspension resulted in a marked increase of turbidity of the suspension and decrease of fluidity of the liposomes.

这可能是因为在脂质体存在的条件下，Al3＋加速了Fe2＋的氧化，且加速作用与脂质体中原先存在的过氧化物的含量有关；另一方面，Al3＋可以引起脂质体的聚集，表现为浊度的增加；测量脂质体上标记的脂肪酸自旋标记物5－ Doxyl stearic acid 的ESR 波谱发现： Al3＋降低了脂质体的膜脂的流动性。

Recombinant plasmid pSVH 7 DNA of avian influenza virus H7 subtype heamagglutinin gene was encapsulated with DC-chol/DOPE liposomes and PC/chol/SA liposomes separately. Two-week old SPF chickens were intramuscularly inoculated with 50 μ g/0.2ml of the liposome entrapped PSVH 7 DNA. Four-weeks later, each chicken was challenged with 0.1ml 〓 AIV . One week after the challenge, the secretion of the cloacas was collected and transfected to chicken embryos to isolate the virus. The virus was isolated from 6/6 of the control group, 1/6 of the naked DNA group, 1/6 of the PC/chol/SA entrapped DNA group and 0/6 of the DC-chol/DOPE liposome entrapped group. The HI antibody titers (log2) of the four groups were 6. 83±0.98, 7. 0±1. 26, 7. 83±1. 17 and 8. 00±0.89 respectively 1-week after challenge, and 8. 5±0.55, 8. 17±0.82, 8. 68±0.45 and 9. 33±0.54 respectively 2-week after challenge. The results showed that inoculation of liposome entrapped DNA significantly enhanced resistance to virosis in animals.

将含禽流感病毒H7亚型血凝素基因的重组质粒pSVH7用DC-chol阳离子脂质体和胆固醇／卵磷脂／十八胺脂质体包裹，免疫2周龄SPF鸡，4周后用同型禽流感病毒进行人工感染，1周后采集泄殖腔分泌物分离病毒，结果未免疫组6／6分离到病毒，裸质粒DNA免疫组1／6分离到病毒胆固醇／卵磷脂／十八胺脂质体包裹DNA免疫组1／6分离到病毒，DC-chol脂质体DNA免疫组没有分离到病毒（0／6）：人工感染后1周各组的HI抗体（Log2）分别为6.38±0.98，7.00±1.26，7.83±1.17，8.00±0.89，2周后为8.50±0.55，8.67±0.82，8.68±0.45，9.33±0.52，脂质体包裹组在同期均高于未免疫组和裸DNA免疫组，表明脂质体包裹质粒DNA免疫动物后，能增加动物对病毒感染的抵抗力和反应能力。

In order to isolate the active compounds in ethyl acetate fraction of Psoralea corylifolia L., activity-guided isolation was performed along with chromatographic techniques. Four active compounds were isolated from ethyl acetate fraction and identified by their NMR spectral data and physical-chemical properties. They are corylin and bavachin, which showed stimulating effect on osteoblastic proliferation and differentiation, isopsoralen and psoralen exhibited activity of promoting cell differentiation in some degree.

为了追踪分离补骨脂乙酸乙酯萃取物中的活性成分，本实验采用多种色谱分离技术，以活性测试为导向，结合波谱技术及理化数据，从补骨脂乙酸乙酯萃取物中分离并鉴定了4个活性化合物的化学结构，它们是具有促进细胞增殖和分化作用的补骨脂异黄酮和补骨脂二氢黄酮，对细胞分化有一定促进作用的异补骨脂素和补骨脂素。

The data shoewed that esculetin, resveratrol enhanced LPL expression up to about 1.2 ~3.5 fold compared with the control group. In addition to fibrates, however, no effect on LPL expression by curcumin was observed. We concluded that esculetin and resveratrol enhanced LPL expression on CHO-K1 cell. We hope that we can apply these drugs to mutant form LPL, furthermore apply theses drugs into clinical treatment.

利用药物处理有转染带有完整人类脂蛋白解脂酶启动子和脂蛋白解脂酶cDNA 序列(-1715 ~+1643)质体的CHO-K1细胞，从细胞培养液以及细胞溶解物中发现，除了curcumin之外所有药物都可以使得细胞培养液以及细胞溶解液内的脂蛋白解脂酶活性有1.2至3.5倍的上升，由此结果可知除了curcumin外，esculetin和白藜芦醇以及其他fibrate药物可降低三酸甘油脂血症。

PON has been shown to be closely associated with lipometabolism by protecting LDL from oxidative modification,decreasing level of ox-LDL and destroying lysophospholipid of ox-LDL .

对氧磷酶由355个氨基酸组成，它与高密度脂蛋白中的载脂蛋白结合，能保护低密度脂蛋白免受氧化修饰，降低体内氧化型低密度脂蛋白水平，并且能破坏氧化型低密度脂蛋白中的溶血磷脂，与脂代谢有密切关系。

Moreover, we compared the transfection efficacy of small unilamellar vesicles and multilamellar vesicles.

本实验并使用了不同种类的正电性脂质、微脂粒中不同莫尔比的正电性脂质及其助手脂质，不同组成的小微泡单层微脂粒及多层微脂粒去比较其基因转殖效果。

Liposome properties and biological behaviors can be controlled by surface modification. Attachments of hydrophilic polymers, such as poly, enable them to have a prolonged circulation time without being opsonized and recognized by mononuclear phagocytic system.

通过表面修饰可以改变脂质体的性质和生物学行为：在脂质体表面修饰亲水性高分子可以阻碍血浆成分的调理作用，减少脂质体被网状内皮系统识别和摄取，使脂质体具有长循环的特点；在脂质体表面修饰特异性的配基，能使脂质体具有主动靶向的特性。

Compared with Simvastatin Tablets and the capsule of Xuezhikang,the effects of Wendan decoction on serum triglycerides,serum total cholesterol,serum LDL-C and serum HDL-C in adult rats with chronic hyperlipidemwere observed after30dates.Result:By using pharmacological meth-od,the results revealed that Wendan decoction could effectively reduce serum of TC,TG,LDL-C levels in the rats with chronic hyperlidemia,it has raisen the concents of blood HDL-C and its function was more effective than the capsule of Xu-ezhikang.

除空白对照组喂基础饲料外，其余各组均采用高脂乳剂灌饲方式建立大鼠高脂血症模型，喂养10日后眼球取血，测得受试动物血清中总胆固醇、总甘油三酯、低密度脂蛋白胆固醇显著升高，说明高脂血症模型复制成功。30日后，运用药理学方法，观察温胆汤对高脂血症成年大鼠血清中TC、TG、LDL-C、高密度脂蛋白胆固醇含量的影响，并与西药辛伐他汀、中成药血脂康进行比较。

The ratios of cholesterol/triglyceride in LDL increased both in hypertriglyceridaemia and complex hyperlipidaemia groups, while showed no difference in hypercholesterolaemia group.

结论高脂血症人群胆固醇酯转运蛋白水平升高，促进了脂蛋白间脂质转运，使高密度脂蛋白和低密度脂蛋白脂质组成发生变化，促进了动脉粥样硬化的发生和发展。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。