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Chapter two, the preparation of liposomes in DPPC/Chol/DPPA mixed system were investigated systematically for the first time. The optimal conditions for preparation and the composition of liposomes were established, the encapsulation efficiency was up to 50.4%.

第二章 首次系统研究了反相蒸发法用于DPPC/Chol/DPPA混合类脂体系的脂质体的制备，确定了脂质体的最佳制备条件和最佳组成，获得了高达50.4％的包裹效率。

Aim To investigate the possible interaction of cholesteryl ester transfer protein level with the lipid transport between the lipoproteins.

目的分析不同高脂血症人群血清胆固醇酯转运蛋白水平及其对血浆各脂蛋白间脂质转运的调节作用。

The coturnix artherosclerosis model was established by feeding with high-fat diet (1% cholesterol, 14% lard, 6% bean oil) and treating it with Yizhikang simultaneously, observing whether serum TC, TG, LDL-c, HDL-c, VLDL-c, liver lipidoses and AO artherosclerotic plaque were resulted at.

用高脂饲料（1%胆固醇，14%猪油，6%豆油，剩余加入基础饲料）喂养复制鹌鹑动脉粥样硬化模型并同时给药，观察益脂康对其血清TC，TG，LDL-c，HDL-c，VLDL-c，肝脏脂质沉积和主动脉粥样硬化斑块形成的影响。

Studies on stability indicated that PHGF proliposomes should be stored at low temperature and against light, which ensured unchange of their redispersity, content of drug, encapsulation efficiency, acid value and peroxide value. Liposomes were multilamellar vesicle structure under transmission electron microscopy. Average particle size was 0.65 micrometer, ranging from 0.09 micrometer to 1.21 micrometer. Cryoscopic value was 0.64 C determined by cryoscopic method, which was a little higher than that of isotonic solution.

以透射电镜观测PHGF前体脂质体再分散后的形态为囊泡状；激光散射法测得平均粒径为0.65μm，且粒度分布在0.09μm～1.21μm之间；该脂质体荷负电，ζ电位为-44.23mV；冰点降低法测得冰点降低度数为0.64℃，略高于等渗溶液冰点降低度数；测得粘度为1.83mPa·s，达到生理要求；此外，对PHGF脂质体的刺激性、溶血性、热原、异常毒性和过敏沈阳药科大学硕士学位论文拘要性检查表明均符合静脉注射给药的标准。

Encapsulated psoralen were evaluated by dialyzation using psoralen gel as the control. Changes of liposome????encapsulated psoralen and release rate were detected during a 3????week storage at 4 ℃ for evaluating the stability of the liposomal formulation.

以同浓度的补骨脂素凝胶为对照，用透析法检测补骨脂素脂质体凝胶的体外释药模式，并对其在4 ℃下贮存3周的释药稳定性进行研究。

The hypercholesterolemic rats were selected to imitate early stage of human atherosclerosis The effects and mechanism of n-3 PUFA on endothelium were investigated with the following parameters: the morphological appearance and arrangement of endothelium stained by Ag, in vitro endothelium-dependentrelaxation of aortic ring, endothelial permeability test using Even′s Blue, blood lipid and body weight in one-week intervals, excitative and emissive spectrum of RBC membrane labeled by DPH (1, 6-Diphenyl-1, 3, 5-hexatriene), fluidity of RBC membrane, plasma and RBC membrane LPO

在整体和离体水平，选用大鼠高脂血症模型模拟动脉粥样硬化早期状况。用114只大鼠多指标着重研究n-3多不饱和脂肪酸在高脂血症状态下对内皮的保护作用，以探讨其预防动脉粥样硬化的机理。所采用指标包括：浸银法观察内皮细胞排列与形态；离体血管环观察内皮依赖性舒张；伊文氏蓝染料法观察内皮通透性。为探讨作用机理，进行了血脂和体重的动态监测、DPH(1，6-二苯基-1，3，5，乙三烯)标记红细胞膜的荧光光谱测定、红细胞膜流动性测定、血浆和红细胞膜脂质过氧化物测定。

The main factors that affected the aiponectin concentration included types of the bioactivity of adiponectin complex; the variance of age, sexuality and race; the change of leptin, tumor necrosis factor-α, glucocorticoid, cAMP and β-adrenoceptor excitomotor, NO and so on; bioactivity of receptors of adiponectin.

运动对脂联素影响方面的研究，结果有很大的不同，有人认为运动训练虽然能够改善糖尿病患者或代谢综合征的胰岛素抵抗，但并不能提高脂联素的水平；还有的研究者认为，运动训练改善胰岛素敏感性和运动训练改善了血浆中脂联素的浓度有关。

Excellent dispersivity in water and stability, acid and basic -resistant, electrolyte -resistant, but also cold-resistant Test on the leather showed that when lubricating with this fat liquor, it makes the leather glazy, flexible, plentiful.

耐酸，碱及电解质溶液。具有很好的耐寒性。应用实验表明，用该加脂剂对皮革进行加脂，可使革身丰满，柔软，富有弹性，具有理想的丝光感。该加脂剂可明显地消除革的部位差和解决松面问题，使用量少。

The addition of green tea at 400 mgkg^(-1) decreased intermuscular fat (P.05), while this decreasing also occurred at treatment of 800 mgkg^(-1) and sebum thickness, but the low-dose tea power had no effect, muscle fat rate slightly decreased, but abdominal fat rate and liver fat rate were not significantly influenced.

对肉鸡腹脂率、肝脂率无明显影响，对胸脂率有降低的趋势，400mgkg^(-1)茶粉组肌间脂肪宽显著降低，800mgkg^(-1)茶粉组肌间脂肪宽、皮下脂肪厚明显降低，但低剂量茶粉组则影响不明显。

Retrospectivly analyse the coronary heart disease, 68 patients diagnosed the coronary angiography, including Unstable Angina the 24 patients, Stable Angina 32 patients, myocardial infarction 12 patients; Compares the change of normal comparison group 35 patients fasting blood lipide:Trighycerides, Total Cholesterol, High Density Lipoprotein Cholesterol, Low Density Lipoprotein Cholesterol, Apolipoproteins (ApoA1 and ApoB), Fasting Blood Glucose, Fasting Insulin, Insulin area under curve and Glucose area under curve.

回顾性分析经冠状动脉造影确诊的冠心病患者68例，其中包括不稳定型心绞痛患者24例，稳定型心绞痛32例，心肌梗塞12例；正常对照组35例的空腹血脂（血清甘油三酯TG、血总胆固醇TC、高密度脂蛋白胆固醇HDL-C、低密度脂蛋白胆固醇LDL-C、载脂蛋白ApoA1及ApoB）、空腹血糖、空腹胰岛素、糖负荷后胰岛素曲线下面积及葡萄糖曲线下面积的变化并进行比较。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。