能结合的

PSE7 and SOJB had the similar binding proteins in tobacco, suggesting that they may share some similar biological functions. The ubiquitin-conjugating protein and peptidase involved in protein degradation were found binding with SOJB but not PSE7. Both SOJB and PSE7 could bind with transmembrane transport protein, SOJB bound with copper transporter protein, and PSE7 bound with water channel protein. The results suggested that the target of SOJB and PSE7 may be located in cytoplast.

PSE7和SOJB在烟草中存在几个相似的结合蛋白，表明二者具有共享的生物学功能；SOJB能与肽酶和泛素结合蛋白（与蛋白质降解有密切关系）互作，而PSE7没有筛选到类似蛋白；SOJB和PSE7均能与跨膜运输蛋白结合，PSE7与水通道蛋白结合，SOJB与铜离子转运蛋白结合，表明二者在胞质内均存在作用靶标。

The interactions of dsDNA and ssDNA with two osmium complexes have been studied by surface electrochemical methods based on DNA modified electrode. It is found that both osmium complexes bond DNA with electrostatic interaction. And some thermodynamics and kinetics constants, such as bindind constant , ratio of binding constants K〓/K〓, limiting ratio K〓°/K〓°at zero ionic strength (μ＝0), free energy ΔG〓, dissociation rate constant k and binding site size s have been obtained.

研究发现两种锇配合物都是通过静电作用与DNA结合，并计算得到联吡啶锇和二氯菲咯啉锇与dsDNA和ssDNA相互作用的结合常数、结合常数比K〓／K〓、μ＝0时极限结合常数比K〓°／K〓°、结合自由能ΔG〓、解离速度常数k和结合位点数s等多个热力学和动力学参数。

Radiolabeled pharmacological binding assay showed: 1 BmK AS bound specifically to a single class of non-interacting binding sites on both rat brain and cockroach nerve cord synaptosomes with high affinity and low low capacity. The association of BmK AS with both synaptosomes was quick to reach equilibrium, but the dissociation seemed to be only partial. The specific binding of BmK AS was independent of membrane potential, and couldn't be modified by veratridine. Moreover, the binding of BmK AS could be inhibited by native BmK AS, BmK AS1, BmK IT2 and BmK IT on both synaptosomes, but not or partially inhibited by BmK Ⅰ and suggesting BmK AS type neurotoxins might bind to a distinct receptor site on mammal and insect sodium channels with a similar manner from β-scorpion toxins.

二。蝎毒素多肽配体与哺乳动物和昆虫靶离子通道受体的药理结合特性及其靶结合位点的研究：经放射性标记结合和竞争抑制实验表明：1）BmK AS在大鼠脑和蟑螂神经索突触体上有单一非协同性高亲和力低结合容量结合位点，能快速结合并达到平衡，但仅能部分解离，其结合不依赖于膜电位，也不受藜芦碱调节，天然的BmK AS，BmK AS-1，BmK IT2和BmK IT可抑制〓AS与两种突触体的特异结合，而BmK Ⅰ无或仅有部分抑制效应。

Spikelets all alike, somewhat laterally compressed, with 1 to several fertile florets; rachilla usually disarticulating below each floret, occasionally strictly 3 florets with lower 2 staminate or barren and of different appearance from upper fertile floret, then disarticulating above glumes and florets falling together; glumes persistent, often equal to spikelet or at least longer than first floret, commonly membranous with broad, shining, hyaline margins; floret callus bearded; lemmas hyaline to leathery, 3- to several-veined ( Coleanthus 1-veined), apex entire or denticulate, awned from back, rarely awnless; awn usually geniculate with twisted column; palea hyaline, subequaling or much shorter than lemma.

全部一样的小穗，有点侧面压扁，具1到数个能育的小花；脱节的通常小穗轴在下面每小花，偶尔严格加雄蕊或者无意义的更低的2的3小花和上面肥沃小花的不同外表，然后脱节的上述颖片和小花结合起来；宿存的颖片，等于小穗或长于前小花，宽的膜质具，发亮，透明边缘的通常的至少的通常；公然反对的小花结茧；透明的外稃到革质，3-到数枚脉(Coleanthus 1脉)，先端全缘或具小齿，从背面，很少awnless那里具芒；用盘旋的柱子通常膝曲的芒；透明的内稃，近相等或者远短于外稃。

The happy combination of youthful gallantry triumphing against overwhelming odds with brainy boffins giving the vital technological edge (through radar, and the brilliantly designed Spitfires and Hurricanes), as well as inspirational leaders using flawless tactics and matchless rhetoric, is irresistible.

不能掩饰的惊喜既结合了面对势力压倒优势的强敌的年轻的英雄主义，聪明的科技人员提供了技术的优势（通过雷达，以及喷火式，飓风式战机的精妙设计），同时也包括了运用了完美策略和无可比拟的修辞技巧的鼓舞人心的领袖。

The binding free energy calculations by the following equation:〓 In first equation, the left parenthesis denotes the absolute free energies associated with complex system G〓 and unbound protein G〓, respectively, while the right parenthesis contains solvated inhibitor G〓 and solvent water G〓.

预测结合自由能的计算公式如下：〓ΔG〓是体系结合自由能，G〓是复合物的绝对自由能，G〓是未结合抑制剂的蛋白质绝对自由能，G〓被溶剂化的抑制剂绝对自由能，G〓溶剂水的绝对自由能。

Meanwhile,HDAC1 acetylation level is significantly increased.The overexpression of HDAC1 can promote erythroid cell proliferation and inhibits induced differentiation,the knockdown of HDAC1 or 2 inhibits erythroid cell proliferation and promotes induced differentiation.We also found that HDAC1 affects GATA1 mediated transcription activity.Thus our data revealed that HDAC1 may negatively regulate GATA1 mediated transcription and suggest that the dynamic regulation of GATA1 associated NuRD/MeCP1/HDAC1/HDAC2 complex may determine the onset of erythroid differentiation programs.Moreover,this study will eventually help to design new therapeutic approaches in treatment of leukemia.

研究发现在被诱导分化的小鼠红细胞白血病细胞中与GATA1相结合的HDAC1被乙酰化并失去活性，在血细胞中过表达HDAC1能够促进血细胞的增殖并抑制分化，反之在血细胞中敲除HDAC1或HDAC2能抑制血红细胞的增殖并促进分化，而且HDAC1能够负调控GATA1的转录活性，GATA1与NuRD/MeCP1复合体之间的动态调控，决定血红细胞分化的发生和发展，并为探索白血病的致病机理奠定了理论基础。

In order to make the right evaluation of the state which is the consumption consume of the steam line system, we make an test of the heat loss of the steam line network. And we also probe into the heat loss of the steam line system and the factors. In order to solve the heat inefficency of the steam line system, we look into the present situation of the steam line network and the state of heat preservation. Then we found the open questions and the weak points of heat preservation. We make the evaluation and affirm the reason of the heat inefficency of the system. We adopted the combination of bench test and engineering optimization, then we screened out high-quality adiabator, and designed the best heating composition. We designed and developed the software"The analysis and optimization of energy of the steam line system in thermal production" It can offer convenience to the computational analysis of heat loss of the steam line system. It can also be used for design calculation and experimental verification of steam pipeline feasible radial-radius, so it can offer technical support for the reduce of heat loss of the system, the raise of well head steam quality and the raise of heat efficicency of the steam injection system.

为了对输汽系统的用能状况作出正确的分析评价，对输汽管线热损失进行了测试计算，对输汽系统热量损失及影响因素进行了探讨；为了解决输汽系统热效率低的问题，从输汽管网现状及管道保温状况调查入手，掌握存在的问题和保温薄弱环节，做出分析评价，确认导致系统热效率低的原因，采用室内试验与工程优化相结合的办法，筛选出优质保温材料，设计最优保温结构，同时设计开发了&热采输汽系统能量分析及优化软件&，为输汽系统热量损失计算分析和保温结构优化提供了方便，还对输汽管线合理辐射半径进行了设计计算及实验验证，从而为降低系统的热能损失，提高井口蒸汽干度，提高注汽系统的热效率提供了技术支持。

Based on the characteristics of parameterized design and key technologies of knowledge based engineering, and specially according to the characteristics of the construction, figure, assembly-parameter of bicycle frame design, the article has achieved repeated using of experiential parameter and knowledge by adopting methods such as automatic reading experiential datasheet, computing parameter by making use of program, manual data-input or modifying and so on. Based on analyzing the characteristics of Rear End design and the associated characteristics with Chain Stay and Seat Stay, different design methods are analyzed in detail, and rapidly assembling of Rear End, Chain Stay and Seat Stay is achieved by using the method of combining top-down-assembly with down-top-assembly method. Based on analyzing special technologies and UDF characteristics, the repeated using of different sectional shapes by using UDF technology on the tube section design is also achieved, and this will greatly shorten the time spent on fixing the dimensions and orientations on sketches.

在探讨了参数化设计技术特点和知识工程关键技术的基础上，针对自行车车架设计中的结构、形状、装配参数特点，分别采用了读入经验数据表、参数程序求解、手工录入或修改方法实现车架设计经验参数和知识的重复利用；在分析自行车后叉片设计特点及与平、立叉的关联特性的基础上，对不同的设计方案进行了详细分析，并采用自顶向下和自底向上相结合的方法，实现了后叉片的快速装配定位与平、立叉设计相关联；在分析了特征技术和UDF特点的基础上，将UDF用于管件截面的设计上，使各种截面形状能不断重复利用，大大节省了约束草图尺寸和位置的时间。

Firstly, micro-thermal calorimeters were used to qualitatively analyze the thermochemistry behaviour of reactants system under adiabatic mode; Subsequently a series of toluene nitration experiments were carried out in an isothermal reaction calorimeter to study the influences of different operating conditions such as stirring speed feeding rate and setting temperature and so on . The thermal hazard assessment of toluene nitration was derived from the measured calorimetric data, the rate of the reaction the adiabatic temperature increase △T_ad and maximal temperature attainable MTSR_max in a runaway situation can also been derived.

首先采用微量热分析仪对反应体系在绝热状态下的热行为进行分析；再采用等温条件下的反应量热器实验研究不同的工艺条件如搅拌速度、加料速度和设定温度等参数对反应结果的影响；结合热分析数据和RCle数据，对甲苯的一段硝化过程进行了初步的热危险分析，推导出反应速率方程、反应失控条件下的绝热温升△T_和反应所能达到的最大温度MTSR等参数。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。