能发育的

Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype.

这种遗传缺陷的小鼠模型并不能令人满意，因为纯合子缺陷动物在发育早期就会死亡，而杂合子又不能显示心脏表型。

Nitric oxide can promote the differentiation of neural stem cells and the growth of neuritis of differentiated cells.

NO能促进神经干细胞的分化，并能促进细胞分化后轴突的发育。

Of the five stages deformation, the exact ages of the (2) and (3) were determined by 40Ar/39Ar method as 290 and 259 Ma respectively.2. New results on the metamorphic belts and associated metamorphism of the Xiaopu metamorphic rocksBased on detailed microtextural observations and occurrence of typical metamorphic minerals, five metamorphic belts in the Xiaopu metamorphic rocks are identified. From the north to the south, they are biotite belt, garnet belt, staurolite belt, andalusite belt, and sillimanite belt. I suggested that the metamorphic belts occurred in the Xiaopu area belongs to the high temperature/low pressure series, may have resulted from the later Permian crust extension at ca. 290 Ma.3. I suggest that there may have been a Carboniferous backarc basin along the southern slope of the Harlik Mountain.Detrital Zircon SHRIMP U-Pb dating indicated that the sedimentary age of the Julideneng formation lithic sandstone must be later than late Devonian, most likely is Carboniferous rather than previously thought Precambrian. Analyses on its geologic setting, location of provenance, and sedimentary environment suggest the Carboniferous strata may form in a lagged backarc basin bounded by backarc uplifts.5. Reconstruction of the post-Paleozoic tectonic evolution history of the Harlik MountainThe tectonic evolution of Harlik mountains since the Paleozoic were reconstructed as followings:(1) arc-affinity magmative activities occurred during the middle-Ordovician to early-Silurian;(2) the middle-Silurian to late-Devonian was a back-arc uplift stage;(3) back-arc extension featured the Carboniferous period;(4) post-collisional extension and/then compression during Permian;(5) at the Mesozoic, differential uplift developed; and (6) the late Cenozoic is the intra-continental re-orogen stage.6. Primary estimation of the crust shortening is madeThe folded pre-Mesozoic strata were used to estimate crust shortening along the Harliknanshankou-Koumenzi, Shichengzi-Baishitou, and Qincheng-Xiaopu sections. Their shortening ratios are 16.2%, 19.8%, and 20.1% respectively corresponding crust shortening are 4.3, 9, and 11.3 km.

根据Ar-Ar热年代学研究，精确测定了早二叠世伸展变形和晚二叠世挤压变形的峰期时代分别为290Ma和259Ma.2、提出了关于哈尔里克山南麓小铺一带变质带和变质作用的新认识根据显微观察资料和特征变质矿物的出现，把小铺一带的变质岩由SW向NE方向依次划分为黑云母带、石榴石带、十字石带、红柱石带和矽线石带等变质带；初步确定该区的变质作用属于中温-低压型，变质作用发生的时代为290Ma左右，是该区早二叠世地壳伸展的产物。3、首次提出哈尔里克山南麓在石炭纪可能发育弧后盆地的新观点根据哈尔里克山南麓原"居里得能组"岩屑砂岩的碎屑锆石SHRIMP U-Pb定年，确认这套地层的沉积不早于晚泥盆世，很可能是石炭纪，而不是前人所说的前寒武纪；结合对其区域地质背景、源区位置和沉积环境分析，推测该区石炭纪可能为滞后弧后盆地和弧后隆起区构造背景。4、进一步证明哈尔里克山不发育与岛弧演化相关的泥盆纪岩浆活动根据对代表性闪长岩和花岗岩的锆石SHRIMP年代学研究获得的新资料，结合该区已有相关资料的综合研究，确定哈尔里克山岩浆岩分别形成于奥陶纪-志留纪和石炭纪晚期-二叠纪，不存在泥盆纪的岩浆岩，进而认为该区泥盆纪不属于岛弧环境。5、重建了哈尔里克山古生代以来的地质演化过程根据区域资料以及本次研究所获得的资料，把哈尔里克山古生代以来的构造演化划分中奥陶世-早志留世为岛弧、中志留世-晚泥盆世为弧后区、石炭纪弧后伸展、二叠纪为后碰撞伸展与挤压、中生代差异隆升和晚新生代陆内再造山过程等构造阶段。6、初步估算了哈尔里克山地壳缩短率和缩短量根据前中生代地层褶皱估算的哈尔里克山南山口-口门子、石城子-白石头和沁城-小铺三条剖面的地壳缩短率分别为16.2%、19.8%和20.1%，相应的地壳缩短量分别为4.3km、9km和11.3km。

Subclones of the hybrid 741 took on a high insect-resistant identity to the larvae of leaf pests such as Clostera anachoreta Fabricius, Lymantria dispar Linnacus, Hyphantria cunea Drury ect., and the mean death rate of the grubs were all above the 85%, furthermore, the grubs' growth which survived could be restrained and the growth rate was reduced so that they couldn't tie cocoons as the usual.

项目简介：转双抗虫基因741杨是将部分改造BtCryIAc 基因与慈菇蛋白酶抑制剂基因，通过农杆菌介导法转化了优良白杨杂种741杨，并获得了一批具有高抗虫性无性系，对舞毒蛾和杨扇舟蛾，美国白蛾等鳞翅目幼虫死亡率达85%以上，并能抑制存活幼虫的发育，使其不能正常化蛹。

The BG100 series osteoporosis treatment meter use curative effect is remarkable, not can only improve the skeleton quality, the prevention bone fracture, to cut the bone fracture formation rate, the acceleration bone fracture cicatrization; May also use in treating the soft tissue damage, osteoarthropathy, the bone not to link, the bone fracture difficultly to heal and so on, and can promote young people's growth.

BG100系列骨质疏松治疗仪使用疗效显著，不但能改善骨骼质量、预防骨折、降低骨折发生率、加速骨折愈合；还可以用于治疗软组织损伤、骨关节病、骨不连、骨折难愈合等，并能促进青少年的生长发育。

We suppose that there is a presently undefined subfraction of stem cell population that exists in a number of tissues beyond embryonic development. We term them postembryonic pluripotent stem cells. They differ from embryonic stem cells in that they gradually lose some differentiation potentials during development and adopt some special phenotypes once within a certain tissue. They can give rise to different kinds of stem cells; therefore, help to maintain balance during development and metabolism. They provide cells not only for the damaged tissues they reside, but also for damaged tissues different from them by migration triggered by proinflammatory cytokines or growth factors.

我们认为在胚胎发育后的多种组织中都存在一类原始干细胞群体，它们和造血干细胞、神经干细胞等多能干细胞不同，后者只能分化为特定胚层的细胞，而这类原始干细胞可分化为不同胚层的组织细胞；另一方面，它们区别于胚胎干细胞，在妊娠期间会逐渐失去部分分化潜能，并且会出现一些特殊表型或者分子标志，我们称其为胚胎后亚全能干细胞，这类干细胞具有下列特性：可分化为不同胚层的细胞，分布于身体的所有组织和器官，具有相同的表型或标志；他们在胚胎期存在于一些或全部的组织和器官中，可分化为不同类型的多能干细胞并在生长发育和新陈代谢中维持这些多能干细胞保持平衡；可以参与机体自我修复和更新，不仅能分化为所在器官的组织特异性细胞，参与器官重塑，也可以在炎症因子或者生长因子的趋化作用下，远处转移修复受损组织。

We tested whether inhibitory GABAergic synaptic transmission regulates Xenopus optic tectal cell dendritic arbor development in vivo by expressing a peptide corresponding to an intracellular loop ofthe gamma2 subunit of type A GABA receptors GABA(AR, which is required to anchor GABA receptors to the postsynaptic scaffold.

我们想证明如下设想：抑制性GABA能突触传递是否能调节早蟾视顶盖细胞的树突发育。因为GABA受体的gamma2亚基有一段细胞内的跨膜端序列，这段序列对锚定GABAA受体到突触后膜是必须的，所以我们的主要方法是设计了一段特异性的争对细胞内段的序列，这样就特异性的阻断了单个细胞GABA能的突触传递。

The results of the determinating the activity of the CA in vitro showed that the CA of the water—fed individuals were in activing statics after eclosion. Because of the apperence of the Vg in haemolymph and the deposition of the vitellin in oocytes in the unfed females, it was shown that the CA in such individuals were in activiting statics, too. Again because in the water—fed females which did not lack the feeding action the activity of the CA showed dropping tendency gradually still, it could be said that the activiting of the CA was possibly effected by the nutrition but it was never related to the adult feeding action. In another respect, the brain of the female adult had not significant effect on the activiting CA. The oocytes could depositing vitellin in individuals removed brain tissue on the day of eclosion, which showed that the activting of CA was not concerned with brain.

CA活性的体外测定说明饲水个体的CA同样具有活性，不取食个体血淋巴中Vg的存在以及卵母细胞中卵黄的沉积表明，在不取食的个体中CA同样具有活性，所以CA的活化与成虫期的取食动作无关，与成虫是否取食花蜜也无太多的联系，但是CA活性的维持可能受成虫期营养的影响，如果以卵母细胞发育和CA体积大小作为CA活性的指标，则饲水个体CA的活性在后期受到了影响，说明饲水不能替代取食蜂蜜来维持成虫期CA的活性；成虫期脑对CA的活化无明显作用，羽化当日摘除脑的个体，其卵母细胞仍然可以沉积卵黄，说明CA的活化与脑无关，而是受某种不确定的因子的影响；用抗JH物质—早熟素—Ⅱ以10ug／虫的剂量在颈部点滴处理雌虫，对Vg的发生和卵巢的发育具有一定的迟缓作用，其原因有待于进一步的研究。

First, the SVZa NSCs continuously migrate from SVZa to olfactory bulb in mammal whole life, form the rostral migratory stream and become the resource of OB interneuron renewing.

与其他部位的神经干细胞相比，SVZa神经干细胞还具有以下特点：(1)自产生时起即具备发育为神经元的特征；(2)迁移过程中保持增殖状态和神经元特征而不进一步分化；(3)到达迁移终点后，才进一步分化为DA能和GABA能神经元。

Of the five stages deformation, the exact ages of the (2) and (3) were determined by 40Ar/39Ar method as 290 and 259 Ma respectively.2. New results on the metamorphic belts and associated metamorphism of the Xiaopu metamorphic rocksBased on detailed microtextural observations and occurrence of typical metamorphic minerals, five metamorphic belts in the Xiaopu metamorphic rocks are identified. From the north to the south, they are biotite belt, garnet belt, staurolite belt, andalusite belt, and sillimanite belt. I suggested that the metamorphic belts occurred in the Xiaopu area belongs to the high temperature/low pressure series, may have resulted from the later Permian crust extension at ca. 290 Ma.3. I suggest that there may have been a Carboniferous backarc basin along the southern slope of the Harlik Mountain.Detrital Zircon SHRIMP U-Pb dating indicated that the sedimentary age of the Julideneng formation lithic sandstone must be later than late Devonian, most likely is Carboniferous rather than previously thought Precambrian. Analyses on its geologic setting, location of provenance, and sedimentary environment suggest the Carboniferous strata may form in a lagged backarc basin bounded by backarc uplifts.5. Reconstruction of the post-Paleozoic tectonic evolution history of the Harlik MountainThe tectonic evolution of Harlik mountains since the Paleozoic were reconstructed as followings:(1) arc-affinity magmative activities occurred during the middle-Ordovician to early-Silurian;(2) the middle-Silurian to late-Devonian was a back-arc uplift stage;(3) back-arc extension featured the Carboniferous period;(4) post-collisional extension and/then compression during Permian;(5) at the Mesozoic, differential uplift developed; and (6) the late Cenozoic is the intra-continental re-orogen stage.6. Primary estimation of the crust shortening is madeThe folded pre-Mesozoic strata were used to estimate crust shortening along the Harliknanshankou-Koumenzi, Shichengzi-Baishitou, and Qincheng-Xiaopu sections. Their shortening ratios are 16.2%, 19.8%, and 20.1% respectively corresponding crust shortening are 4.3, 9, and 11.3 km.

根据Ar-Ar热年代学研究，精确测定了早二叠世伸展变形和晚二叠世挤压变形的峰期时代分别为290Ma和259Ma.2、提出了关于哈尔里克山南麓小铺一带变质带和变质作用的新认识根据显微观察资料和特征变质矿物的出现，把小铺一带的变质岩由SW向NE方向依次划分为黑云母带、石榴石带、十字石带、红柱石带和矽线石带等变质带；初步确定该区的变质作用属于中温-低压型，变质作用发生的时代为290Ma左右，是该区早二叠世地壳伸展的产物。3、首次提出哈尔里克山南麓在石炭纪可能发育弧后盆地的新观点根据哈尔里克山南麓原&居里得能组&岩屑砂岩的碎屑锆石SHRIMP U-Pb定年，确认这套地层的沉积不早于晚泥盆世，很可能是石炭纪，而不是前人所说的前寒武纪；结合对其区域地质背景、源区位置和沉积环境分析，推测该区石炭纪可能为滞后弧后盆地和弧后隆起区构造背景。4、进一步证明哈尔里克山不发育与岛弧演化相关的泥盆纪岩浆活动根据对代表性闪长岩和花岗岩的锆石SHRIMP年代学研究获得的新资料，结合该区已有相关资料的综合研究，确定哈尔里克山岩浆岩分别形成于奥陶纪-志留纪和石炭纪晚期-二叠纪，不存在泥盆纪的岩浆岩，进而认为该区泥盆纪不属于岛弧环境。5、重建了哈尔里克山古生代以来的地质演化过程根据区域资料以及本次研究所获得的资料，把哈尔里克山古生代以来的构造演化划分中奥陶世-早志留世为岛弧、中志留世-晚泥盆世为弧后区、石炭纪弧后伸展、二叠纪为后碰撞伸展与挤压、中生代差异隆升和晚新生代陆内再造山过程等构造阶段。6、初步估算了哈尔里克山地壳缩短率和缩短量根据前中生代地层褶皱估算的哈尔里克山南山口-口门子、石城子-白石头和沁城-小铺三条剖面的地壳缩短率分别为16.2%、19.8%和20.1%，相应的地壳缩短量分别为4.3km、9km和11.3km。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。