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Increases of APP transcript and expression by HupA also contribute to the up-regulation of sAPPα secretion. Meanwhile, Aβ secretion was observed to decrease 2 h after HupA treatment, and after 24 h incubation, HupA can significantly inhibit the secretion of Aβ.

Real-time PCR和Western blotting结果提示石杉碱甲能增加APP的转录和表达,该作用也将有助于对sAPPα分泌的上调;同时Aβ的生成并未相应增加,ELISA检测结果显示石杉碱甲孵育2 h后即能对Aβ分泌产生抑制作用,孵育24 h后能显著降低Aβ水平。

Because of ovary and spermary not developing in babyhood, the estrogen in serum is mainly from adrenal, and the low level of estrogen persists until prepuberty.

雌激素是一类具有广泛生物活性的甾体激素,主要由卵巢分泌,睾丸及肾上腺也能分泌少量。

It was observed that sphingomyelin plays a negative regulatory role on the activity of 〓, resulting in a strong inhibition on 〓-induced cell death.

我们观察到,鞘磷脂对分泌型磷脂酶〓的活性起着负调控作用,它能有效的抑制分泌型磷脂酶〓对细胞的杀伤作用。

Itwas observed that sphingomyelin plays anegative regulatory role on the activity of sPLA 2, resulting in a strong inhibition on sPLA 2-induced cell death.

我们观察到,鞘磷脂对分泌型磷脂酶A 的活性起着负 2 调控作用,它能有效的抑制分泌型磷脂酶A 2对细胞的杀伤作用。

He thyrotropin-releasing hormone is a bioactive peptides Synthesized and excreted from hypoghaiamus. It is the mainphysiological action that stimulates the Synthesis of antehypophysis, release of thyroid-stimulating hormone and excretion of prolactin.

RH是由下丘脑合成和分泌的活性肽之一,主要生理作用是促进垂体前叶合成和释放促甲状腺素,并能促进催乳素的分泌,它又是一种中枢神经谏U激剂,可以细8精神抑郁症。

Conus is one group of the tropical carnivorous marine molluscs belonging to the mollusk gate gastropoda prosobranchia stenoglossa branch conidae family. The venom from cone snails contains a diverse mixture of pharmacological agents, mostly small, disulfide-rich structurally constrained peptides.

芋螺属于软体动物门腹足纲前鳃亚纲狭舌目的芋螺科,是一类能分泌有毒毒素的肉食性热带海洋软体动物,其分泌的毒素称为芋螺毒素(Conotoxin,CTX)。

These transgenic cells were able to secrete hEGF protein to certain extent, and have the biological activities to enhance the growth rate of Hacat cells in vitro. Conclusion: Adult epidermal keratinocytes in vitro transfected with exogenetic hEGF cDNA can express and secrete active hEGF.

质粒pcDNA3.1-hEGF在脂质体介导下成功转染成人皮肤角质形成细胞,转基因细胞能分泌有生物活性的EGF;体外培养的成人皮肤角质形成细胞可见少量EGF分泌。

LH may be involved in the functional regulation of fundic glands through autocrine or paracrine activity.

大鼠胃壁细胞和胃主细胞既能产生LH,又能表达LHR,说明LH对胃壁细胞和胃主细胞功能作用可能是通过旁分泌或自分泌的作用来实现的。

Oligodenderocyte and oligodendroglioma cells in vitro were able to secret beta-trace protein and explained why the concentration of β-tp in CSF was higher than that in serum, it was suggested that the level of β-tp released depended on both of cell member and type.

胶质细胞和人脑胶质瘤细胞能分泌β-tp,细胞分泌β-tp水平的高低由细胞类型及细胞的多寡决定。

The main virulence factors are CPS, LPS, OMP, TBP, adhesion factors, Apx, Urease and so on. A. pleuropneumoniae produces proteinaceous cytotoxins that is the main virulence factors, ApxⅠ, ApxⅡ, ApxⅢand ApxⅣ. ApxⅡis expressed by all serotypes of A.

Apx毒素是APP最主要的毒力因子,现证明不同血清型的菌株可产生4种Apx,ApxⅡ除血清型10和14以外,其它血清型都分泌;任何血清型都能在体内分泌毒素蛋白ApxⅣ,但体外培养的细菌却不能分泌该毒素。

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I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里,举止就文雅一些,因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计,这件高贵的制服是香港本土制造,是我们第一套不配帽子的制服。

Do not 'inflate' your achievements and/or qualifications or skills .

不要 '夸大' 你的业绩或成果,条件或者技能。