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Patients with mech-anical injuries to corpus callosum, e,g., tumor compression, anterior or posterior cerebral artery infarction may have in neurological defects including left apraxia, left alexia or anomia to colors. Nevertheless, these symptoms may not occur in congenital corpus callosum agenesis, complete or incomplete.

胼胝体的后天缺损常造成患者左侧失用症及左侧失读症等右大脑无法取得左大脑资讯的症状;然而先天性胼胝体完全或部分缺损(complete or incomplete congenital corpus callosum agenesis)却不见得会有这些症状,相对的,它伴随其他症候群的机会则很大。

The main function of corpus callosum is to connect bilateral hemispheres.

胼胝体的主要功能为联系两侧大脑半球。

The presence of the entire pericallosal artery confirms the presence of a normal corpus callosum.

完整的胼胝体周围动脉证实了正常胼胝体的存在。

Patients had alien hand syndrome (11%), 17 patients had history of hypertention (54.83%) 16 patients had coronary artery heart disease (51.61%), 10 patients had diabetes mellitus (32.25%), 9 patients had history of cerebral infarction (29.03%), 17 patients had disorders of conciousness and mental (54.83%), 18 patients had language disorder (58.1%), 21 patients had disorders of limbs in different degrees (74.19%). MRI imaging of 22 patients showed previous cerebral infarction focuses (70.96%), 16 patients with leukoaraiosis (61%), 9 patients with angiostenosis (29%), stenosis was over 60% in 6 patients, and 7 patients showed cerebral microbleeding (22.58%). There were 34 focus of copus callusum infarctions in 31 patients.

异手综合征者3例(11%),高血压病史17例(54.83%),冠心病16例(51.61%),糖尿病10例(32.25%),脑梗死史者9例(29.03%),神志和精神异常的17例(54.83%),语言障碍的患者18例(58.1%),21例(74.19%)患者有不同程度肢体运动障碍。31例胼胝体梗死患者,共34处胼胝体梗死病灶,胼胝体梗死的患者合并其它部位陈旧性梗死灶22例(70.96%),伴有白质稀疏16例(61%),发现血管狭窄9例(29%,其中狭窄超过60%者6例),有7例(22.58%)伴有微出血。

Though there are multiple sites like deep gray matter and posterior fossa (middle cerebellar peduncles,cerebellum,brainstem) that are also involved, the callosal lesions are more distinct.

虽然病变可以见于多处,如深部的脑灰质、后颅窝,胼胝体的病变是最特殊的。

The corpus callosum is not isible in the standard transerse iews of the brain but agenesis of the corpus callosum may be suspected by the absence of the caum septum pellucidum and the 'teardrop' configuration of the lateral entricles (enlargement of the posterior horns).

诊断:正常在脑的标准横切面上看不到胼胝体,通常通过透明隔腔小时和侧脑室的泪滴状改变怀疑有胼胝体的发育不良,确诊胼胝体发育不良需要在正中冠状面和正中矢状面上,一般需要做阴道B超显示。

CT scan and MRI both revealed acute left anterior cerebral artery infarction involving cingulated gyrus and corpus callosum. His right side weakness gradually improved after rehabilitation.

脑部电脑断层及核磁共振扫描均显示为左侧前大脑动脉急性梗塞造成左侧额叶扣带脑回区及胼胝体的病灶,病患右侧肢体无力的现象经复健后逐渐改善。

Center the image on the interpeduncular cistern.

胼胝体的图像置中

Of the 19 cases,19 fetus were found,MRI confirmed 14 cases considered or suspected as fetal corpus callosum agenesis by US(8 cases are completed agenesis of corpus collosom-CACC,6 cases are partial agenesis of corpus collosom-PACC, and 5 cases had took on autopsy),however 3 cases are mild enlargement of lateral cerebral ventricle and 2 cases are leukodystrophy.In these cases,MRI confirmed a Dandy-Walker syndrome and a lipoma of corpus callosum suspected by US,detect a Dandy-Walker syndrome and a microcephalus made missed diagnoses by US.The fetal corpus callosum and additional cerebral anomalies were shown more clearly on MR T_2-weighted images.

胎儿胼胝体长度与额枕径的比值在24~36孕龄阶段相对较恒定。2、19例孕妇共检出胎儿19个,MRI证实超声疑诊的胎儿胼胝体发育不全14例(完全型胼胝体发育不全8例,部分型胼胝体发育不全6例,有胎儿尸检结果对照者5例),3例为单纯侧脑室轻度扩张,2例考虑脑白质发育不良,合并Dandy—Walker综合征1例,胼胝体脂肪瘤1例,检出超声漏诊合并Dandy-Walker综合征1例及脑小畸形1例。

Results: ADC in MS group was increased in all regions of NAWM compared to controls(P<0.05),significantly higher in the body of corpus callosum, internal capsule, periventricular WM, frontal WM, parietal WM and occipital WM(P<0.01). FA value in MS group was decreased in the body of corpus callosum, internal capsule, periventricular WM, frontal WM, parietal WM and occipital WM(P<0.05), the genu and splenium of CC,middle cerebellar peduncle showed an insignificant trend of lower FA.

结果:MS组的正常表现脑白质的ADC值均高于对照组(P<0.05),以胼胝体体部、内囊、侧脑室旁及额、顶、枕叶脑白质更为显著(P<0.01);MS组的FA值与对照组比较,胼胝体体部、顶、额、枕叶白质及内囊、侧脑室旁发现明显降低(P<0.05),以后4个部位更为显著(P<0.01),而胼胝体膝部、压部和小脑结合臂有降低趋势,但无统计学意义。

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