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Similarly NAC was also protective in a bleomycin fibrosis model. Moreover, amiodarone, a benzofuran compound with redoxcycling properties induces oxidative lung injury.

同时NAC也对由博来霉素所介导的纤维化模型有保护作用;此外,胺碘酮和苯基呋喃类化学物,具有氧化还原环,可介导肺的氧化损害。

Hepatic sinusoid capillarization plays an important role in occurrence of portal hypertension. The fenestra of endothelial cells in hepatic sinusoid reduces and the diameter of fenestra decreases. The formation of basement membrane impaires the substance exchange between blood and hepatic cells,which results in oxygen deficiency, metabolic product accumulation and cell necrosis.

肝窦毛细血管化在硫代乙酰胺诱导的肝硬化门脉高压发生中起重要作用,肝窦内皮细胞窗孔减少并减小,内皮细胞下基底膜形成使肝细胞与外界物质交换减少,导致细胞缺氧、代谢产物聚集,肝细胞坏死,最终导致门脉高压的发生。

AIM: To investigate the therapeutic effects and mechanism of thalidomide on hepatic fibrosis in rats.

摘要目的:观察沙利度胺对大鼠实验性肝纤维化的治疗效果并探讨其作用机制。

Objective To investigate the effects of rotenone on the accumulation of the ubiquitinated α-synuclein and cellular injury.

目的 探讨鱼藤酮对多巴胺能神经元内泛素化α-synuclein聚集的影响及其细胞损伤作用。

The N-alkylation of N-monosubstituted sulfonamide s with alkyl halides promoted by KF using ionic liquids as reaction media was reported in this paper.

报道了KF作用下离子液体介质中N-单取代磺酰胺和卤代烃的N-烷基化反应,考察了4种不同结构的离子液体BF4、BF4和PF6对反应的影响。

It was found that the reactions of C_(60) with anthranilic acids and isoamyl nitrite in the presence of triethylamine unexpectedly afforded C_(60)-fusedδ-lactones,which would be difficult to be prepared by other known methods.

通过在三乙胺作用下,富勒烯与邻氨基苯甲酸类化合物和亚硝酸异戊酯的环化反应,首次合成了一系列富勒烯并六元环内酯。

A series of 2-acetylformanilides were prepared,followed by thiolation with Lowesson reagent to afford 2-acetylthioformanilides,which further reacted with Mn3·2H2O in glacial acetic acid under microwave irradiation to afford 2-acetyl benzothiazole s.

合成了一系列的硫代酰胺,研究了它们在微波辐射醋酸锰作用下发生氧化自由基环化反应,成功地合成了一系列2-乙酰基苯并噻唑衍生物,其结构经红外光谱、核磁共振谱和质谱得到了证实

Objective: To compare the effect of ipratropium bromide with sulbutamol, on bronchodilatation in patients with asthma and COPD.

目的:比较溴化异丙托品气雾剂与沙丁胺醇气雾剂分别使用及联合应用对哮喘和COPD患者的支扩作用。

Methods: A model to evaluate lymphocyte proliferation stimulated with a polyclonal activator, concanavalin A, was established by vital dye carboxyl fluorescin diacetate succinmidyl ester labeling technique. Effects of the different doses of anisomycin on the lymphocyte proliferation were estimated by flow cytometry and MTT methods. The propidium iodide labeling technique was applied to assay the effect of the different doses of anisomycin on changes of the lymphocyte cell-cycle stimulated by ConA or by phorbol ester plus Ionomycin. The percentage of the expression level of CD69 and CD25 on the activated lymphocytes was evaluated by fluorescin-conjugated monoclonal antibody double labeling technique.

以活体染料羧基荧光素乙酰乙酸琥珀酰亚胺酯染色,建立在多克隆刺激剂刀豆蛋白A刺激下评价小鼠淋巴细胞增殖的模型,通过流式细胞术和MTT法分析茴香霉素在不同剂量下对淋巴细胞增殖的作用;采用碘化丙锭染色分析茴香霉素对ConA或佛波醇酯加离子霉素刺激的小鼠淋巴细胞周期变化的作用;利用荧光标记的单克隆抗体双染技术和流式细胞术观察茴香霉素对小鼠CD3~+T细胞早期及中期活化标志分子CD69和CD25表达的影响。

Gel-type cross-linked polystyrene-isocyanuric acid resin has been obtained by reaction of chloromethylated polystyrene with isocyanuric acid under the existence of triethylamine.

由氯甲基化低交联聚苯乙烯和异氰尿酸在三乙胺作用下反应,制得了凝胶型交联聚苯乙烯-异氰尿酸树脂,测定了该树脂对苯酚和间苯二酚在不同温度下的吸附等温线,依据Clapeyron-Clausius方程从吸附等温线计算出了吸附热,从热力学的角度论证了树脂是基于氢键键合和疏水作用而吸附苯酚和间苯二酚的。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力