胺化

A novel series of naphthalimide dendrimers has been synthesized, into whose dendron novel specific function units are introduced. The absorption and fluorescence properties of the arrays were studied and discussed. Excitation of the terminal donor chromophores carbazole mainly results in the fluorescence of the core dye alone, whose efficiency is dependent on the dendrimer generation.

在树枝上引入特定的功能单元，将多个具有特定功能团连接起来，形成功能化树枝状周边分子团簇，然后将它们分别与核心色素萘酰亚胺相连接，合成新型周边树枝状功能化的有机发光材料。

Teflubenzuron was synthesized from 2,4-difluoronitrobenzene and 2,6-dichlobenil as starting reagent through six-step reaction with the yield of 75.3%.3,5-Dichloro-2,4-difluoroaniline was synthesized by chlorination,reduction reaction from 2,4-difluoronitrobenzene,the yield was 84.5%;2,6-difluorobenzamide with the yield of 87.7% was synthesized by fluoridation and hydrolysis from 2,6-dichlobenil.

以2，4-二氟硝基苯和2，6-二氯苯腈为起始原料，经过6步反应合成伏虫隆，总收率为75.3%。以2，4-二氟硝基苯为原料，经过氯化、还原反应合成3，5-二氯-2，4-二氟苯胺，产率为84.5%；以2，6-二氯苯腈为原料，经过氟化和水解，制得2，6-二氟苯甲酰胺，产率为87.7%；将Ⅱ与二碳酸酯酰化，合成2，6-二氟苯甲酰异氰酸酯，产率为91.3%；Ⅲ与Ⅰ加成，得到杀虫剂伏虫隆，产率为95%。

Methods 4-Hydroxybenzonitrile (2) as the starting material was transformed to 4-hydroxy-thiobenzamide (3) via thioformylation. And ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (4), which was synthesized via cyclization from 3, was treated with hexamethylenetetramine to generate the intermediate ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (5). The target compound febuxostat (1) was obtained from 5 by etherification, cyanidation, hydrolysis.

以羟基苯腈为原料，经硫代甲酰化得到对羟基硫代苯甲酰胺(3)，3经环合得到2-（4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(4)，4与乌洛托品反应，得到中间体2-（3-甲酰基－4-羟基苯基）－4-甲基－噻唑－5-羧酸乙酯(5)，之后再经醚化、氰化、水解得到目标产物(1)。

The quaternary ammonium salt of quinoline synthesized by alkyl halide and quinolin etc.,can be used as corrosion inhibiter during acidizing treatment of oil well when it is compounded with organic amine,suitable solvent and surfactant.

以烷基卤化物与喹啉等原料合成的喹啉季铵盐，当其与有机胺、适当溶剂、表面活性剂复配后，可作为油井酸化作业的酸化缓蚀剂。

Using ethylenediamine, urea, methanal and formic acid as base material, 1, 3-dimethyl-2-imidazolidinone was prepared via cyclization reaction and methylation.

以乙二胺、尿素、甲醛和甲酸为原料，经过环化和甲基化反应制得目标产物1，3-二甲基－2-咪唑啉酮(1，3-DMI)。

An abnormal condition caused by excessive intake of fluorine ,as from fluoridated drinking water,characterized chiefly by mottling of the teeth.

氟中毒由于过量摄入氟而导致牙齿产生色斑的不正常状况，如饮用氟化的水全氟胍可以由于的三聚氰酰胺，用5%的氟在约－16℃直接进行氟化制得。

Amino to acetyl phenol, in have technology of two kinds of production domestic and internationally, acetic anhydride craft of the United States, acyl changes temperature to have 75 ℃ only, acyl changes mother liquor not apply mechanically, deputy reaction is little, of production thick tasting is kind of white almost, purificatory craft is very simple, activated carbon dosage only 2~3%, the Kun that its product does not have glow material almost in different third alcohol inferior the sealed impurity of amine impurity and minim, settleclear lightness it may not be a bad idea, the product quality that acetic anhydride craft produces is good, but close rate low, cost is high.

对乙酰氨基酚，在国内外有两种生产工艺，美国的醋酐工艺，酰化温度只有75℃，酰化母液不套用，副反应少，生产的粗品几乎是类白色，精制工艺就非常简单，活性炭用量仅2~3%，其产品在异丙醇中几乎无红光物质的醌亚胺杂质及微量的未知杂质，澄明度也好，醋酐工艺生产的产品质量好，但收率低、成本高。

The results show that the sulfonation degree of the final pmducts under the condition of temperature 80~90℃, pH≥11 and reaction time 80-90 min is higher than that under other conditions.

研究表明，在pH＞11.5，温度为80~90℃和合适的时间内可以获得高磺化程度的三聚氰胺磺酸盐；在摩尔比F/M=4.0和S/M=1.0的反应体系中，磺化可同时发生在仲氮和叔氮原子上，两种结构之比约为2：1。

METHODS: Based on the antitumor activity and structural feature of 8-chloroadenosine and retinoic acid, modifications were made at positions 5′ and 8,substituted cinnamoyl and benzoyl groups were bound at 8 position through amido and ester bonds, sulfonation and nitrosation at 5′-OH and its direct chlorination were conducted.

对腺苷的8位和8-Cl-腺苷的糖环羟基进行了结构改造，以酰胺键和酯键在腺苷的8位连接了具共轭基团的肉桂酰基和苯甲酰基，得到腺苷的维甲类似物；对8-Cl-腺苷的5′-羟基进行了甲磺酰化，硝基化以及氯代反应，得到了它的衍生物。

A series of novel bile acid derivatives as potential hepato-biliary and intestinal scintigraphy imaging SPECT (single photon emission computed tomography) tracers were prepared from bile acids by es-terification, aminolysis of esters and alkylation of amino groups.

以胆酸、鹅去氧胆酸为起始原料，经羧基的酯化、酯的胺解以及氨基的烷基化，合成了一系列潜在的针对肝胆显像和肠显像的SPECT (Single photon emission computed tomography)分子探针前体。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新