胺化

In this paper, acetanilide used as start material was chlorosulfonated, then reacted with alkylamines with different length of carbon chain to prepare 4 p-acetylaminophenylsulfonylalkylamine.

本文以乙酰苯胺为起始原料，经氯磺化后分别和不同碳链的正烷基胺反应制得4种不同碳链长度的对乙酰氨基苯磺酰烷基胺，将其水解后制得了对氨基苯磺酰正丁胺、对氨基苯磺酰正辛胺、对氨基苯磺酰正十二胺和对氨基苯磺酰正十八胺。

For the synthesis of NHC precursors, there are also several routes: condensation of glyoxal, amines and paraformaldehyde; alkylation of imidazole or monosubstituted imidazole with alkyl halide; annulation of ortho esters and 1,2-diamines; ring closure of hydrazines or amides with acetic anhydride; reduction of thiones with Na/K in THF.

关于N-杂环卡宾前体的合成途径主要有：乙二醛、伯胺和多聚甲醛的缩合反应；卤代烷与咪唑及其取代咪唑的烷基化反应；原甲酸酯与1，2-二胺的成环反应；肼或酰胺与酸酐的环化反应；用Na/K对环硫脲化合物的还原反应。

Two bispyrazolylimine nickel complexes [bis-N-(phenyl-1,3,5-dimethylpyrazolylmethylene) phenylimine nickel dibromide] (Cat.1) and [bis-4-methoxy-N-(phenyl-1,3,5-dimethylpyrazolylmethylene) phenylimine nickel dibromide] (Cat.2) were synthesized.

合成了两种双吡唑亚胺镍配合物：双－N-（苯基－1-3，5-二甲基吡唑基亚甲基）苯基亚胺二溴化镍Cat.1）和双－4-甲氧基－N-（苯基－1-3，5-二甲基吡唑基亚甲基）苯基亚胺二溴化镍

A series of 2-oxocyclododecyl sulfonylurea s have been synthesized from 2-oxocyclododecylsulfonamide via acylation of phenyl chloroformate and amination.

以环十二酮为起始原料，经磺化反应制备得到2-氧代环十二烷基磺酸盐B，B经过氯化和胺解反应制备得到2-氧代环十二烷基磺酰胺C，C经过苯氧酰化与胺解反应后合成了10个新的2-氧代环十二烷基磺酰脲类化合物D，它们的结构通过了1HNMR和IR的确证。

Immunohistochemistry technology was used to evaluated tyrosine hydroxylase of DA synthesis. DA, 5-hydroxytryptophan(5-HT) and their respective metabolic products 3,4 -dihydroxyphenylacetic, homovanillic are also precisely quantified in this research by using high-pressure liquid chromatography with electrochemical detector. The main metabolism monoamine oxidase of DA was processed too. RESULTS:WD can increase the synthesis and the metabolism process of DA .

本文观察了温胆汤及其配伍对大鼠刻板行为的影响，采用了免疫组化技术对多巴胺的合成酶—酪氨酸羟化酶进行了含量测定，应用高效液相-电化学法测定了DA、5-羟色胺（5-HT）及代谢产物3，4—二羟基苯乙酸、高香草酸的含量，并测定了DA主要降解酶—单胺氧化酶。

Ornithine decarboxylase, a rate-determining enzyme of the polyamine biosynthetic pathway, is involved in the control of cell cycle, differentiation, cell growth and apoptosis. Previous studies described that protein kinase Cd regulates ODC activity. In this thesis, human leukemia cell line, HL60 cell, was used for the treatment with a specific PKCd inhibitor, rottlerin, to measure the effects on cell growth.

鸟胺酸去羧化（ornithine decarboxylase，ODC）为多胺酸起始与决定反应速率的酵素，对细胞周期、细胞生长、分化及细胞凋亡扮演一重要角色；在寻找肿瘤治疗及预防药物研究中，纯化植物天然物质是其中来源之一，研究者筛选药物时，测定对鸟胺酸去羧化活性是否具抑制效果是一个重要的试验。

In the Aldol condensation of acetone with 4-nitrobenzaldehyde, two different hybrid secondary amine-functionalized mesoporous materials displayed enhanced catalytic performance in comparison to primary amine-functionalized materials. The possible reason is that the presence of organic functional groups with larger steric hindrance led to the enhanced catalytic performance of basic amino groups.

在对硝基苯甲醛和丙酮的羟醛缩合反应中，相对于一级胺功能化的材料，二级胺功能化的SBA-15展示了极大改进的催化活性，这可能是由于具有更大空间位阻效应的有机功能团的引人导致了碱性胺中心催化活性增强。

The therapeutic problems posed by class D beta-lactamases, a family of serine enzymes that hydrolyse beta-lactam antibiotics following an acylation-deacylation mechanism, are increased by the very low level of sensitivity of these enzymes to beta-lactamase inhibitors.

丝氨酸酶一个科能水解β-内酰胺抗生素和随后进行酰化和脱酰化机理， D类β-内酰胺酶引起的治疗问题，随着这些对β-内酰胺酶抑制剂的酶的非常低敏感性而不断增加。

Nanocrystalline copper tellurides Cu〓Te〓 and Cu〓Te〓 have been successfully prepared in ethylenediamine and ethylenediamine with hydrazine hydrate system under high-intensity ultrasonic irradiation at room temperature respectively. Nanocrystalline silver tellurides Ag〓Te and Ag〓Te〓 have been successfully prepared in ethylenediamine and ethanol system under high-intensity ultrasonic irradiation at room temperature respectively.

在制备碲化铜时，在纯乙二胺体系超声辐射所制备的最终产物为Cu〓Te〓，而在加有水合肼的乙二胺中制得的产物为Cu〓Te〓；在制备碲化银时，在乙二胺体系制备的产物为Ag〓Te，而在乙醇体系制备的产物为Ag〓Te〓。

Then, it was condensed with-valine methyl ester to form a chiral imine, which was reacted with allyl zinc bromide in the presence of CeCl3·7H2O to afford the corresponding chiral homoallylic amine with high optical activity.

-N-Boc-3-苯基-2-氨基丙醛与-缬氨基酸甲酯缩合生成手性亚胺，在七水合三氯化铈（CeC13·7H2O）催化以及底物的手性诱导作用下，该手性亚胺与烯丙基溴化锌经不对称加成反应合成了高光活性的单烯丙基化手性胺。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。