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Results: The most common locations of PIP were at the margin of both lower lobes and associated with local pleural thickening and adhesion. The density of nodule in which CT attenuation value was 15~60 HU (26.9±13.5HU) was lower than that of PLC. Most of them were round/round-like and irregular in shape. The interior density of lesion was inhomogeneous. The presence of calcification or multiple cavitations, straight margin sign, hole sign and without hilar and mediastinal adenopathy were of great significance in the diagnosis of such kind of disease.

结果:炎性假瘤多位于两肺下叶,邻近胸膜增厚、粘连,病灶密度偏低(平扫CT值15~60HU,平均26.9±13.5HU),与周围型肺癌比较有统计学差异,其形态以圆形/类圆形和不规则形多见,病灶内密度多不均匀,可见钙化及多发空洞,边缘呈平直状、周围见毛玻璃样改变及肺门纵隔无淋巴结肿大等征象对本病的CT诊断有意义。

CT scanning can provide more information about peripheral pulmonary carcinoma than routine X-ray.The lobulation,spicules and pleural indentation around the mass suggest the diagnosis of pulmonary carcinoma.

CT诊断周围型肺癌比常规X线检查提供更多的信息;若CT发现肺部周围结节或肿块有分叶、毛刺及胸膜凹陷征等应考虑为肺癌,肺门、隆突下及纵隔淋巴结肿大且无钙化时,要考虑肺癌向淋巴结转移。

Results The anatomic structures of "Jianzhongshu" for perpendicular insertion downward were skin, superficial fascia, trapezius, rhomboideus, splenius cervicis, erector spinae, suprapleural membrane and cupula of pleura in order.The anatomic structures of "Dazhu" were skin, superficial fascia, trapezius, rhomboideus, upper posterior serratus, splenius cervicis, erector spinae, levator ribs, internal intercostal membrane and costal pleura in order.

结果 肩中俞向下直刺的解剖结构依次是皮肤、浅筋膜、斜方肌、菱形肌、颈夹肌、竖脊肌、胸膜上膜、胸膜顶;大杼穴向下直刺的解剖结构依次是皮肤、浅筋膜、斜方肌、菱形肌、上后锯肌、颈夹肌、竖脊肌、肋提肌、肋间内膜、肋胸膜。

Results The anatomic structures of "Jianzhongshu" for perpendicular insertion downward were skin, superficial fascia, trapezius, rhomboideus, splenius cervicis, erector spinae, suprapleural membrane and cupula of pleura in order.The anatomic structures of "Dazhu" were skin, superficial fascia, trapezius, rhomboideus, upper posterior serratus, splenius cervicis, erector spinae, levator ribs, internal intercostal membrane and costal pleura in order.

结果 肩中俞向下直刺的解剖结构依次是皮肤、浅筋膜、斜方肌、菱形肌、颈夹肌、竖脊肌、胸膜上膜、胸膜顶;大杼**向下直刺的解剖结构依次是皮肤、浅筋膜、斜方肌、菱形肌、上后锯肌、颈夹肌、竖脊肌、肋提肌、肋间内膜、肋胸膜。

Recognition of the mistake was delayed because of the rare incidience of extrapleural insertion and the difficulty in diagnosis by plain chest radiography.

由於胸管胸膜外置放是非常少见,而且很难在胸部X光下诊断,所以要正确的诊断,不能只靠胸部X光。

The HRCT findings in patients with BOOP include: 1 patchy consolidation (seen in 80% of cases) or ground-glass opacity (in 60% of cases), often with a subpleural and/or peribronchial distribution; and 2 small ill-defined nodules (30-50% of cases) which may be peribronchial or peribronchiolar.

HRCT上BOOP的表现包括:1、斑片状实变(见于80%的病例)或毛玻璃样影(见于60%的病例),通常位于胸膜下和/或支气管旁;和2、边界不清的小结节(见于30~50%的病例),可于支气管旁或细支气管旁。

The stimulations of dexamethasone, lipopolysaccharide, erythromycin and hypertonic saline can significantly change the AQP1 expression in pleura, which indicate that AQP1 may contribute to the accumulation and clearance of pleuritic fluids. Aquaporin-1;Pleura;Pleural effusion;Dexamethasone;Lipopolysaceharide;Erythromycin;Hypertonic saline

地塞米松、内毒素、红霉素和高渗盐水刺激下胸膜组织AQP1表达的改变,提示存在炎症因子和渗透梯度下调控AQP1的途径,胸膜组织上AQP1可能参与了炎症性胸腔积液的分泌和吸收。

HRCT scan showed peripheral area of ground-glass attenuation adjacent to subpleural honeycombing in one patient,and diffusely distributed ground-glass opacity in another patient.Two patients had received cortieosteroid treatment.For one patient, the symptoms improved, and ground-glass attenuation adjacent to subpleural honeycombing had almostly resolved.The other patient died of respiratory failure.

其中1例患者的双肺新出现的磨玻璃影,沿胸膜下蜂窝肺外周分布;另1例患者HRCT表现为新出现的磨玻璃影呈弥漫性分布。2例患者均接受激素治疗。1例患者气紧、咳嗽症状明显缓解,胸部HRCT的磨玻璃样影基本吸收;另1例患者死于呼吸衰竭。

Abnormal pleurae were biopsied in sight of thoracoscopy and compared with blind needle biopsy for pleurae.

对114例经常规检查未明确病因的疑难性胸液患者,采用胸腔镜直视下于病变处取组织行活组织检查,并与经皮盲目胸膜活检对比。

The apxⅢA gene of Actinobacillus pleuropneumonie was amplified by PCR. The amplified DNA fragment 3 466bp was cloned into pMD18-T. After R.E. analysis and sequencing, the apxⅢA gene in pMD18-T was ligated into pBluescripⅡSK, the recombinant expression plasmid pET-28b/apxⅢA was constructed and analysed with R.E., the protein of apxⅢA gene expressed in E.coli BL21 was detected by Western blotting.

因胸膜肺炎放线杆菌的致病性主要是由毒素决定的,故参照猪胸膜肺炎放线杆血清2型菌株的序列(GenBankL1 2 1 4 5)设计了一对特异性引物,用PCR的方法扩增apxⅢA基因并得到了长 3 466bp的片段,然后将其克隆到pMD 1 8T中,经酶切鉴定和序列分析表明克隆是成功的;再将apxⅢA插入到原核表达载体pET 2 8b后,转化BL2 1 (DE3),在IPTG诱导下获得高效表达,经Westernblotting检测证实表达产物有活性。

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